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  3. Glycyl-Exatecan D5 hydrochloride

Glycyl-Exatecan D5 hydrochloride (Synonyms: Glycyl-DX-8951 D5 hydrochloride; Exatecan analog 2 D5 hydrochloride)

Cat. No.: HY-128995AS
Handling Instructions

Glycyl-Exatecan (D5 hydrochloride) is deuterium labeled Glycyl-Exatecan hydrochloride.

For research use only. We do not sell to patients.

Glycyl-Exatecan D5 hydrochloride Chemical Structure

Glycyl-Exatecan D5 hydrochloride Chemical Structure

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Description

Glycyl-Exatecan (D5 hydrochloride) is deuterium labeled Glycyl-Exatecan hydrochloride.

Molecular Weight

533.99

Formula

C₂₆H₂₁D₅ClFN₄O₅

SMILES

FC(C=C1N=C2C3=CC([[email protected]](O)4C(C([2H])([2H])[2H])([2H])[2H])=C5COC4=O)=C(C)C6=C1C([[email protected]@H](NC(CN)=O)CC6)=C2CN3C5=O.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 110 mg/mL (206.00 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8727 mL 9.3635 mL 18.7269 mL
5 mM 0.3745 mL 1.8727 mL 3.7454 mL
10 mM 0.1873 mL 0.9363 mL 1.8727 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.75 mg/mL (5.15 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 2.75 mg/mL (5.15 mM); Clear solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: 2.75 mg/mL (5.15 mM); Suspended solution; Need ultrasonic

*All of the co-solvents are provided by MCE.
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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Glycyl-Exatecan D5Glycyl-DX-8951 D5Exatecan analog 2 D5OthersInhibitorinhibitorinhibit

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Product Name:
Glycyl-Exatecan D5 hydrochloride
Cat. No.:
HY-128995AS
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