Laquinimod-d5
Based on 1 Customer Validation
Laquinimod-d5 (ABR-215062-d5) is deuterium labeled Laquinimod. Laquinimod (ABR-215062), an orally available carboxamide derivative, is a potent immunomodulator that prevents neurodegeneration and inflammation in the central nervous system. Laquinimod reduces astrocytic NF-κB activation to protect from Cuprizone-induced demyelination. Laquinimod has the potential for relapsing-remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS) as well as neurodegenerative diseases research.
For research use only. We do not sell to patients.
- Purity: 98.25%
- CAS No.: 1214267-09-0
- Formula: C19H12D5ClN2O3
- Molecular Weight:361.83
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1214267-09-0
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Unlabeled Cas 248281-84-7
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Appearance Solid
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Molecular Weight 361.83
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Formula C19H12D5ClN2O3
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Color White to light yellow
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SMILES
[2H]C1=C([2H])C([2H])=C(N(C(C2=C(O)C3=C(N(C)C2=O)C=CC=C3Cl)=O)CC)C([2H])=C1[2H]
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Synonyms
ABR-215062-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (276.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7637 mL | 13.8186 mL | 27.6373 mL | 69.0932 mL |
| 5 mM | 0.5527 mL | 2.7637 mL | 5.5275 mL | 13.8186 mL | |
| 10 mM | 0.2764 mL | 1.3819 mL | 2.7637 mL | 6.9093 mL | |
| 15 mM | 0.1842 mL | 0.9212 mL | 1.8425 mL | 4.6062 mL | |
| 20 mM | 0.1382 mL | 0.6909 mL | 1.3819 mL | 3.4547 mL | |
| 25 mM | 0.1105 mL | 0.5527 mL | 1.1055 mL | 2.7637 mL | |
| 30 mM | 0.0921 mL | 0.4606 mL | 0.9212 mL | 2.3031 mL | |
| 40 mM | 0.0691 mL | 0.3455 mL | 0.6909 mL | 1.7273 mL | |
| 50 mM | 0.0553 mL | 0.2764 mL | 0.5527 mL | 1.3819 mL | |
| 60 mM | 0.0461 mL | 0.2303 mL | 0.4606 mL | 1.1516 mL | |
| 80 mM | 0.0345 mL | 0.1727 mL | 0.3455 mL | 0.8637 mL | |
| 100 mM | 0.0276 mL | 0.1382 mL | 0.2764 mL | 0.6909 mL |
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