Nor-Acetildenafil-d8
Nor-Acetildenafil-d8 is the deuterium labeled Nor-Acetildenafil. Nor-Acetildenafil is an Acetildenafil derivative. Acetildenafil is a synthetic agent which acts as a phosphodiesterase inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 1185117-07-0
- Formula: C24H24D8N6O3
- Molecular Weight:460.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1185117-07-0
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Unlabeled Cas 949091-38-7
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Molecular Weight 460.60
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Formula C24H24D8N6O3
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SMILES
CCCC1=NN(C)C2=C1NC(C3=C(C=CC(C(CN4C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C4([2H])[2H])C)=O)=C3)OCC)=NC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Samuel R Gratz, et al. Accurate Mass Measurement Using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for Structure Elucidation of Designer Drug Analogs of Tadalafil, Vardenafil and Sildenafil in Herbal and Pharmaceutical Matrices. Rapid Commun Mass Spectrom. 2006;20(15):2317-27. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nor-Acetildenafil-d8 Related Classifications
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