Gluconate-d6 sodium
Gluconate-d6 sodium (D-Gluconic acid sodium salt-d6) is the deuterium labeled Gluconate sodium (HY-B1092A). Gluconate sodium (D-Gluconic acid sodium salt) is an orally active glucose derivative. Gluconate sodium reduces nitric oxide and inflammatory cytokines (IL-1β and IL-6). Gluconate sodium inhibits ERK phosphorylation. Gluconate sodium has antioxidant and antiplatelet activation activities. Gluconate sodium has antitumor activity against colorectal cancer. Gluconate sodium improves osteoarthritis, intestinal damage and acute lung injury.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C6H5D6NaO7
- 분자량:224.17
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 527-07-1
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분자량 224.17
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화학식 C6H5D6NaO7
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SMILES
O[C@@]([C@@]([C@]([C@](C([2H])([2H])O)([2H])O)([2H])O)([2H])O)([2H])C(O[Na])=O
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Synonyms
D-Gluconic acid sodium salt-d6; Sodium D-gluconate-d6; D-Gluconate sodium salt-d6
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[2]. Saluk-Juszczak J. A comparative study of antioxidative activity of calcium-D-glucarate, sodium-D-gluconate and D-glucono-1,4-lactone in a human blood platelet model. Platelets. 2010;21(8):632-40. [Content Brief]
[3]. Kameue C, et al. Dietary sodium gluconate protects rats from large bowel cancer by stimulating butyrate production. J Nutr. 2004 Apr;134(4):940-4. [Content Brief]
[4]. Saleem TH, et al. Possible Protective Effects of Quercetin and Sodium Gluconate Against Colon Cancer Induction by Dimethylhydrazine in Mice. Asian Pac J Cancer Prev. 2015;16(14):5823-8. [Content Brief]
[5]. Zhang Y, et al. Dietary supplementation with sodium gluconate improves the growth performance and intestinal function in weaned pigs challenged with a recombinant Escherichia coli strain. BMC Vet Res. 2022 Aug 6;18(1):303. [Content Brief]
[6]. Kang SJ, et al. Protective effects of calcium gluconate on osteoarthritis induced by anterior cruciate ligament transection and partial medial meniscectomy in Sprague-Dawley rats. J Orthop Surg Res. 2014 Mar 7;9(1):14. [Content Brief]
[7]. Liu L, et al. Effects of calcium gluconate on lipopolysaccharide-induced acute lung injury in mice. Biochem Biophys Res Commun. 2018 Sep 18;503(4):2931-2935. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Gluconate-d6 sodium Related Classifications
HY-B1092AS2 Related Classifications
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