Ergothioneine-d9
Based on 1 publication(s) in Google Scholar
Ergothioneine-d9 is the deuterium labeled Ergothioneine. Ergothioneine, an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant.
For research use only. We do not sell to patients.
- Purity: 99.80%
- Formula: C9H6D9N3O2S
- Molecular Weight:238.35
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Ergothioneine-d9
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 497-30-3
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Appearance Solid
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Molecular Weight 238.35
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Formula C9H6D9N3O2S
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Color White to off-white
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SMILES
S=C1NC(C[C@@H](C([O-])=O)[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=CN1
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Synonyms
L-(+)-Ergothioneine-d9
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
H2O : 50 mg/mL (209.78 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Oumari M, et al. Regeneration of ergothioneine after reaction with singlet oxygen. Free Radic Biol Med. 2019 Apr;134:498-504. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.1955 mL | 20.9776 mL | 41.9551 mL | 104.8878 mL |
| 5 mM | 0.8391 mL | 4.1955 mL | 8.3910 mL | 20.9776 mL | |
| 10 mM | 0.4196 mL | 2.0978 mL | 4.1955 mL | 10.4888 mL | |
| 15 mM | 0.2797 mL | 1.3985 mL | 2.7970 mL | 6.9925 mL | |
| 20 mM | 0.2098 mL | 1.0489 mL | 2.0978 mL | 5.2444 mL | |
| 25 mM | 0.1678 mL | 0.8391 mL | 1.6782 mL | 4.1955 mL | |
| 30 mM | 0.1399 mL | 0.6993 mL | 1.3985 mL | 3.4963 mL | |
| 40 mM | 0.1049 mL | 0.5244 mL | 1.0489 mL | 2.6222 mL | |
| 50 mM | 0.0839 mL | 0.4196 mL | 0.8391 mL | 2.0978 mL | |
| 60 mM | 0.0699 mL | 0.3496 mL | 0.6993 mL | 1.7481 mL | |
| 80 mM | 0.0524 mL | 0.2622 mL | 0.5244 mL | 1.3111 mL | |
| 100 mM | 0.0420 mL | 0.2098 mL | 0.4196 mL | 1.0489 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Ergothioneine-d9 Related Classifications
HY-N1914S1 Related Classifications
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