1. Membrane Transporter/Ion Channel
    Stem Cell/Wnt
    MAPK/ERK Pathway
    NF-κB
    Apoptosis
  2. Sodium Channel
    MEK
    ERK
    NF-κB
    Apoptosis
  3. Lidocaine-d10 N-Oxide

Lidocaine-d10 N-Oxide 

Cat. No.: HY-B0185S
Handling Instructions

Lidocaine-d10 N-Oxide is the deuterium labeled Lidocaine. Lidocaine (Lignocaine) inhibits sodium channels involving complex voltage and using dependence. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia.

For research use only. We do not sell to patients.

Lidocaine-d10 N-Oxide Chemical Structure

Lidocaine-d10 N-Oxide Chemical Structure

CAS No. : 851528-10-4

Size Stock
2.5 mg Check price and availability
25 mg Check price and availability

* Please select Quantity before adding items.

Other Forms of Lidocaine-d10 N-Oxide:

Top Publications Citing Use of Products

View All MEK Isoform Specific Products:

View All ERK Isoform Specific Products:

View All NF-κB Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Lidocaine-d10 N-Oxide is the deuterium labeled Lidocaine. Lidocaine (Lignocaine) inhibits sodium channels involving complex voltage and using dependence[1]. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

260.40

Formula

C14H12D10N2O2

CAS No.
SMILES

N(C(CN(C(C([2H])([2H])[2H])([2H])[2H])(C(C([2H])([2H])[2H])([2H])[2H])=O)=O)C1=C(C)C=CC=C1C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Lidocaine-d10 N-Oxide
Cat. No.:
HY-B0185S
Quantity:
MCE Japan Authorized Agent: