Umirolimus-d5
Based on 1 Customer Validation
Umirolimus-d5 is the deuterium labeled Umirolimus (HY-122402). Umirolimus, a macrocyclic triene lactone Rapamycin derivative, is powerful immunosuppressant and anti-inflammatory agent. Umirolimus has highly lipophilicity and can be used agent-eluting stent (DES) applications.
For research use only. We do not sell to patients.
- Purity: 99.96%
- Formula: C55H82D5NO14
- Molecular Weight:991.31
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 851536-75-9
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Appearance Solid
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Molecular Weight 991.31
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Formula C55H82D5NO14
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Color White to off-white
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SMILES
O=C1N2[C@](CCCC2)([H])C(O[C@](CC([C@@H](/C=C([C@H]([C@H](C([C@@H](C[C@@H](/C=C/C=C/C=C([C@H](C[C@@]3([H])O[C@@](C1=O)([C@@H](CC3)C)O)OC)\C)C)C)=O)OC)O)\C)C)=O)([H])[C@H](C)C[C@H]4C[C@H]([C@@H](CC4)OCCOC([2H])([2H])C([2H])([2H])[2H])OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (100.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0088 mL | 5.0438 mL | 10.0877 mL | 25.2192 mL |
| 5 mM | 0.2018 mL | 1.0088 mL | 2.0175 mL | 5.0438 mL | |
| 10 mM | 0.1009 mL | 0.5044 mL | 1.0088 mL | 2.5219 mL | |
| 15 mM | 0.0673 mL | 0.3363 mL | 0.6725 mL | 1.6813 mL | |
| 20 mM | 0.0504 mL | 0.2522 mL | 0.5044 mL | 1.2610 mL | |
| 25 mM | 0.0404 mL | 0.2018 mL | 0.4035 mL | 1.0088 mL | |
| 30 mM | 0.0336 mL | 0.1681 mL | 0.3363 mL | 0.8406 mL | |
| 40 mM | 0.0252 mL | 0.1261 mL | 0.2522 mL | 0.6305 mL | |
| 50 mM | 0.0202 mL | 0.1009 mL | 0.2018 mL | 0.5044 mL | |
| 60 mM | 0.0168 mL | 0.0841 mL | 0.1681 mL | 0.4203 mL | |
| 80 mM | 0.0126 mL | 0.0630 mL | 0.1261 mL | 0.3152 mL | |
| 100 mM | 0.0101 mL | 0.0504 mL | 0.1009 mL | 0.2522 mL |
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