Pyridoxine-d5
Based on 1 Customer Validation
Pyridoxine-d5 (Pyridoxol-d5) is a deuterium labeled Pyridoxine (HY-B1328). Pyridoxine (Pyridoxol) is a pyridine derivative. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 688302-31-0
- Formula: C8H6D5NO3
- Molecular Weight:174.21
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 688302-31-0
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Unlabeled Cas 65-23-6
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Appearance Solid
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Molecular Weight 174.21
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Formula C8H6D5NO3
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Color White to off-white
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SMILES
OCC1=C(O)C(C([2H])([2H])[2H])=NC=C1C([2H])([2H])O
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Synonyms
Pyridoxol-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (574.02 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246. [Content Brief]
[2]. Li C, et al. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. Cell Mol Biol (Noisy-le-grand). 2018 Jul 30;64(10):119-124. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.7402 mL | 28.7010 mL | 57.4020 mL | 143.5050 mL |
| 5 mM | 1.1480 mL | 5.7402 mL | 11.4804 mL | 28.7010 mL | |
| 10 mM | 0.5740 mL | 2.8701 mL | 5.7402 mL | 14.3505 mL | |
| 15 mM | 0.3827 mL | 1.9134 mL | 3.8268 mL | 9.5670 mL | |
| 20 mM | 0.2870 mL | 1.4350 mL | 2.8701 mL | 7.1752 mL | |
| 25 mM | 0.2296 mL | 1.1480 mL | 2.2961 mL | 5.7402 mL | |
| 30 mM | 0.1913 mL | 0.9567 mL | 1.9134 mL | 4.7835 mL | |
| 40 mM | 0.1435 mL | 0.7175 mL | 1.4350 mL | 3.5876 mL | |
| 50 mM | 0.1148 mL | 0.5740 mL | 1.1480 mL | 2.8701 mL | |
| 60 mM | 0.0957 mL | 0.4783 mL | 0.9567 mL | 2.3917 mL | |
| 80 mM | 0.0718 mL | 0.3588 mL | 0.7175 mL | 1.7938 mL | |
| 100 mM | 0.0574 mL | 0.2870 mL | 0.5740 mL | 1.4350 mL |
Pyridoxine-d5 Related Classifications
HY-B1328S Related Classifications
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