Ivermectin B1a-d2-1
Ivermectin B1a-d2-1 is the deuterium labeled Ivermectin B1a (HY-126937). Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310). Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19.
For research use only. We do not sell to patients.
- Formula: C48H72D2O14
- Molecular Weight:877.11
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 71827-03-7
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Molecular Weight 877.11
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Formula C48H72D2O14
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SMILES
C[C@H]1[C@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](OC)C2)[C@@H](OC)C[C@]([H])(O[C@H](/C(C)=C/C[C@]3([H])C[C@H](O4)C[C@@]5(O[C@]([H])([C@@](CC)([H])C)[C@@H](C)C([2H])[C@H]5[2H])O3)[C@@H](C)/C=C/C=C(CO6)/[C@@]([C@@]6([H])[C@H](O)C(C)=C7)(O)[C@]7([H])C4=O)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Naftale Kat, et al. Ivermectin Efficacy Against Biomphalaria, Intermediate Host Snail Vectors of Schistosomiasis. J Antibiot (Tokyo). 2017 May;70(5):680-684. [Content Brief]
[2]. Khan Sharun, et al. Ivermectin, a New Candidate Therapeutic Against SARS-CoV-2/COVID-19. Ann Clin Microbiol Antimicrob. 2020 May 30;19(1):23. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)