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Cat. No.: HY-179551S

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(±)11(12)-EET-d₁₁ Methyl ester

(±)11(12)-EET-d₁₁ Methyl ester is the deuterium labeled (±)11(12)-EET methyl ester (HY-139938). (±)11(12)-EET methyl ester is a methylated derivative of 11,12-epoxyeicosatrienoic acid (11,12-EET) (HY-130494). (±)11(12)-EET methyl ester cannot induce β-arrestin recruitment of the G protein-coupled receptor GPR132. (±)11(12)-EET methyl ester fails to enhance the expression of hematopoietic stem and progenitor cell (HSPC) markers. (±)11(12)-EET methyl ester can be used as a negative control molecule to study the structure-function relationship of 11,12-EET, facilitating the analysis of the role of the oxygenated fatty acid-GPR132 signaling axis in hematopoiesis.

For research use only. We do not sell to patients.

Formula: C₂₁H₂₃D₁₁O₃
Molecular Weight:345.56

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (244 KB)

(±)11(12)-EET-d₁₁ Methyl ester Chemical Structure

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Fluorescent Dye

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Biological Activity
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Biological Activity

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Molecular Weight 345.56
Formula C₂₁H₂₃D₁₁O₃
SMILES

[2H]C([2H])(C([2H])(/C=C\C[C@@H]1[C@H](C/C=C\C/C=C\CCCC(OC)=O)O1)[2H])C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H].[2H]C([2H])(C([2H])(/C=C\C[C@H]2[C@@H](C/C=C\C/C=C\CCCC(OC)=O)O2)[2H])C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.