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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
155 Results for "
glucuronide metabolite
" in MedChemExpress (MCE) Product Catalog:
Products (155)
155 Results for "glucuronide metabolite" in MCE Product Catalog:
12
12 Publications Verification
Synonyms: Quercetin 3-O-glucuronide; Quercetin 3-glucuronide
Category:
Flavonols other families Flavonoids Phenols Polyphenols Plants Endogenous metabolite Disease Research Fields Cancer
Target:
5
5 Cited Publications
Cat. No.: HY-N7176
CAS No.: 22688-78-4
Synonyms: Kaempferol-3-glucuronide; Kaempferol-3-O-glucuronide
Category:
Flavonols other families Flavonoids Microorganisms Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology
Target:
2
2 Cited Publications
Synonyms: Ezetimibe glucuronide; Ezetimibe β-D-glucuronide
Target:
Research Areas:
Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity . Ezetimibe is a potent cholesterol absorption inhibitor .
1
1 Cited Publications
Cat. No.: HY-N7755
CAS No.: 14982-12-8
Research Areas:
Estradiol 3-glucuronide sodium is an estrogen metabolite, which is a glucuronide conjugate formed by the catalysis of uridine diphosphate glucuronosyltransferase in tissues such as the liver from Estradiol (HY-B0141). Estradiol 3-glucuronide sodium is a potent substrate of Mrp2, with an S50 of 55.7 μM. Estradiol 3-glucuronide sodium achieves hepatobiliary transport in hepatocytes through basolateral uptake via OATP1B1, OATP1B3 and OATP2B1, as well as apical efflux via MRP2 and BCRP .
1
1 Cited Publications
Cat. No.: HY-W585842
CAS No.: 15270-30-1
Research Areas:
Estradiol 3-glucuronide is an estrogen metabolite, which is a glucuronide conjugate formed from Estradiol (HY-B0141) via catalysis by uridine diphosphate glucuronosyltransferases in tissues such as the liver. Estradiol 3-glucuronide is a potent substrate of Mrp2, with an S50 value of 55.7 μM. Estradiol 3-glucuronide achieves hepatobiliary transport in hepatocytes through basolateral uptake via OATP1B1, OATP1B3 and OATP2B1, as well as apical efflux via MRP2 and BCRP .
1
Target:
1
1 Cited Publications
Cat. No.: HY-N2481
CAS No.: 36948-76-2
Synonyms: Oroxyloside; Oroxylin A-7-O-β-D-glucuronide
1
1 Cited Publications
Category:
Monophenols Ketones, Aldehydes, Acids Other Diseases Phenols Endogenous metabolite Disease Research Fields
Target:
1
1 Cited Publications
Target:
Research Areas:
Gemfibrozil 1-O-β-Glucuronide, a metabolite of Gemfibrozil (CI-719; HY-B0258), is a potent and competitive P450 (CYP) isoform CYP2C8 inhibitor with an IC50 of 4.07 μM .
1
1 Cited Publications
Cat. No.: HY-41982
CAS No.: 32449-92-6
Synonyms: D-Glucurono-6,3-lactone; D-Glucurono-γ-lactone; D-Glucuronolactone; Dicurone; Glucoxy; Glucurolactone; Glucurone
Cat. No.: HY-W008917
CAS No.: 15087-01-1
Target:
Research Areas:
Estrone 3-glucuronide sodium is a metabolite of 17-Estradiol .
Cat. No.: HY-W040047
CAS No.: 1852-49-9
Target:
Target:
Research Areas:
Curcumin-β-D-glucuronide is a major metabolite after oral intake of Curcumin in hepatic tissue and portal blood. Curcumin-β-D-glucuronide can be used for the research of colon cancer .
Synonyms: 3'-Azido-3'-deoxythymidine β-D-glucuronide sodium
Target:
Research Areas:
Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the glucuronide conjugate and metabolite of Zidovudine (HY-17413), which can be used to detect UGT2B7 activity. As a substrate, Zidovudine O-β-D-glucuronide sodium undergoes deconjugation via hydrolysis by immobilized β-glucuronidase to produce Zidovudine .
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Target:
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Mycophenolic acid glucuronide is a metabolite of the immunosuppressant mycophenolic acid (MPA). Mycophenolic acid glucuronide shows anti-tumor activity and can be used in adenocarcinoma research .
Cat. No.: HY-135582
CAS No.: 182507-22-8
Target:
Research Areas:
Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene. Raloxifene 4'-glucuronide formation is mediated mostly by UGT1A10 and UGT1A8. Raloxifene 4'-glucuronide binds to estrogen receptor with an IC50 of 370 μM. . Raloxifene is a selective estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression .
Cat. No.: HY-W585920
CAS No.: 208038-27-1
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Research Areas:
Chenodeoxycholic acid 24-acyl-β-D-glucuronide is a metabolite of Chenodeoxycholic Acid (HY-76847) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
