2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. Cipepofol glucuronide

Cipepofol glucuronide  (Synonyms: Ciprofol Glucuronide)

Cat. No.: HY-176515 Purity: 99.92%
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Cipepofol glucuronide (Ciprofol Glucuronide) (M4) is a glucuronide metabolite of Ciprofol (HY-116152). Cipepofol glucuronide has no significant inhibitory activity toward P450s and UDP-glucuronosyltransferases (UGTs), and it has a lower risk of acting as a perpetrator for drug-drug interactions (DDIs). Cipepofol glucuronide can be used for anesthesia research.

For research use only. We do not sell to patients.

Cipepofol glucuronide

Cipepofol glucuronide Chemical Structure

CAS No. : 3118400-26-0

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Based on 1 publication(s) in Google Scholar

Cipepofol glucuronide Related Antibodies

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Description

Cipepofol glucuronide (Ciprofol Glucuronide) (M4) is a glucuronide metabolite of Ciprofol (HY-116152). Cipepofol glucuronide has no significant inhibitory activity toward P450s and UDP-glucuronosyltransferases (UGTs), and it has a lower risk of acting as a perpetrator for drug-drug interactions (DDIs). Cipepofol glucuronide can be used for anesthesia research[1].

Molecular Weight

380.43

Formula

C20H28O7
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@H](C1CC1)C2=CC=CC(C(C)C)=C2O[C@@H]3O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]3O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (131.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6286 mL 13.1430 mL 26.2860 mL
5 mM 0.5257 mL 2.6286 mL 5.2572 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6286 mL 13.1430 mL 26.2860 mL 65.7151 mL
5 mM 0.5257 mL 2.6286 mL 5.2572 mL 13.1430 mL
10 mM 0.2629 mL 1.3143 mL 2.6286 mL 6.5715 mL
15 mM 0.1752 mL 0.8762 mL 1.7524 mL 4.3810 mL
20 mM 0.1314 mL 0.6572 mL 1.3143 mL 3.2858 mL
25 mM 0.1051 mL 0.5257 mL 1.0514 mL 2.6286 mL
30 mM 0.0876 mL 0.4381 mL 0.8762 mL 2.1905 mL
40 mM 0.0657 mL 0.3286 mL 0.6572 mL 1.6429 mL
50 mM 0.0526 mL 0.2629 mL 0.5257 mL 1.3143 mL
60 mM 0.0438 mL 0.2191 mL 0.4381 mL 1.0953 mL
80 mM 0.0329 mL 0.1643 mL 0.3286 mL 0.8214 mL
100 mM 0.0263 mL 0.1314 mL 0.2629 mL 0.6572 mL
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Cipepofol glucuronide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cipepofol glucuronide3118400-26-0Ciprofol GlucuronideDrug MetaboliteGlucuronide metaboliteCiprofolP450sUDP-glucuronosyltransferasesUGTsDrug-drug interactionsDDIsAnesthesiaInhibitorinhibitorinhibit

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