ED-594
ED-594 is the glucuronide form of NB-506. ED-594 is one of the major metabolites of NB-506 in rat bile, mouse liver microsomes, rat liver microsomes and human liver microsomes.
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- CAS No.: 217187-87-6
- 화학식: C33H30N4O16
- 분자량:738.61
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
ED-594 (15-30 min) is formed via glucuronidation of NB-506 in mouse, rat, and human liver microsomes with distinct apparent kinetic parameters, and no ED-594 formation occurs in dog liver microsomes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 217187-87-6
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분자량 738.61
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화학식 C33H30N4O16
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SMILES
O=C1C2=C3C(N([C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)C5=C(O)C=CC=C53)=C6C(C7=CC=CC(O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)C(O)=O)=C7N6)=C2C(N1NC=O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Takenaga N, et al. In vitro metabolism of a new anticancer agent, 6-N-formylamino-12, 13-dihydro-1,11-dihydroxy-13-(beta-D-glucopyranosil)5H-indolo+ ++[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (NB-506), in mice, rats, dogs, and humans. Drug Metab Dispos. 1999 Feb;27(2):213-20. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ED-594 Related Classifications
HY-182255 Related Classifications
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