118 Results for "

growth regulation

" in MedChemExpress (MCE) Product Catalog:
Products (118)

118 Results for "growth regulation" in MCE Product Catalog:

30
30 Publications Verification
Cat. No.: HY-P7077
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T Cell growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In regulation Of T-Cell Clonal Expansion; TCGF; T-Cell growth Factor; Interleukin-2; Lymphokine
Species:  
Mouse
Source:  
E. coli
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24
24 Cited Publications
Cat. No.: HY-164388
CAS No.: 162852-62-2
Z-VAD is an irreversible, broad-spectrum pan-caspase inhibitor that can inhibit a variety of caspases including caspase-3, -6, -7, -8, -9, etc. (with a weaker inhibitory effect on caspase-2). Z-VAD can block apoptosis signaling pathways, induce autophagy and necrosis in tumor cells, and has anti-angiogenic activity. Z-VAD can enhance the sensitivity of breast cancer and lung cancer cells to radiotherapy in vitro and in vivo, and prolong the growth delay of tumor xenograft models. Z-VAD is well tolerated and is mainly used in research related to cancer radiosensitization and cell death pathway regulation .
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24
24 Cited Publications
Cat. No.: HY-P7037
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T Cell growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In regulation Of T-Cell Clonal Expansion; TCGF; T-Cell growth Factor; Interleukin-2; Lymphokine
Species:  
Human
Source:  
E. coli
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22
22 Cited Publications
Cat. No.: HY-107738
CAS No.: 95975-55-6
Purity:  99.81%
Synonyms: Z/E-Guggulsterone
Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt . Guggulsterone, a farnesoid X receptor (FXR) antagonist, with IC50s of 24.06 μM and 39.05 μM for (-)-(E)-Guggulsterone (HY-N7781) and (Z)-Guggulsterone (HY-110066), respectively .
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5
5 Cited Publications
Cat. No.: HY-P7037B
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T Cell growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In regulation Of T-Cell Clonal Expansion; TCGF; T-Cell growth Factor; Interleukin-2; Lymphokine
Species:  
Human
Source:  
E. coli
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5
5 Cited Publications
Cat. No.: HY-P70758
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T Cell growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In regulation Of T-Cell Clonal Expansion; TCGF; T-Cell growth Factor; Interleukin-2; Lymphokine
Species:  
Human
Source:  
HEK293
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4
4 Cited Publications
Cat. No.: HY-113416
CAS No.: 651-48-9
Purity:  99.93%
Synonyms: DHEA sulfate; Prasterone sulfate
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
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4
4 Cited Publications
Cat. No.: HY-B0765
CAS No.: 1099-87-2
Synonyms: DHEA sulfate sodium; Prasterone sulfate sodium
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium salt has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate sodium salt can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium salt participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium salt may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
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4
4 Cited Publications
Cat. No.: HY-13265
CAS No.: 935881-37-1
Purity:  98.52%
Synonyms: HDAC-42; OSU-HDAC42
Target:  

HDAC Autophagy Apoptosis

Research Areas:  

Cancer

AR-42 (HDAC-42; OSU-HDAC42) is a potent, orally bioavailable pan-HDAC inhibitor (IC50=16 nM). AR-42 induces growth inhibition, cell-cycle arrest, apoptosis, and activation of caspases-3/7. AR-42 promotes hyperacetylation of H3, H4, and alpha-tubulin, and up-regulation of p21. AR-42 shows cytotoxicity against various human cancer cell lines .
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4
4 Cited Publications
Cat. No.: HY-120821
CAS No.: 1839524-44-5
Purity:  99.17%
Synonyms: ES2
Target:  

Exosomes

Research Areas:  

Others

Endosidin-2 (ES2) is a selective inhibitor targeting the conserved exosome subunit EXO70. Endosidin-2 binds to the C-terminal domain of EXO70, inhibiting exocytosis and endosomal recycling, while promoting vacuolar trafficking in plant cells. Endosidin-2 interferes with the EXO70-mediated vesicle-to-plasma membrane anchoring process, leading to abnormal aggregation of auxin transporters (such as PIN2) in the cytoplasm and redirected to vacuolar degradation, while causing abnormal Golgi structure (such as cup-shaped or ring-shaped vesicles cisternae formation). Endosidin-2 can inhibit exocytosis in plant and mammalian cells and is mainly used to study the dynamic regulation of membrane trafficking (such as polar growth, vesicle sorting) .
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2
2 Cited Publications
Cat. No.: HY-113679
CAS No.: 100403-19-8
Target:  

Telomerase

Research Areas:  

Metabolic Disease Endocrinology

Ceramides Mixture is an endogenous ceramide and consists of hydroxy and non-hydroxy fatty acid-containing ceramides. Ceramides Mixture is a main lipid component of the permeability barrier in epidermis. Ceramides Mixture is involved in the regulation of growth inhibition, cell cycle arrest, and modulation of telomerase activity .
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1
1 Cited Publications
Cat. No.: HY-135794
CAS No.: 32694-37-4
Purity:  ≥98.0%
Synonyms: 11-KDHT; 5α-Dihydro-11-keto testosterone
Target:  

Androgen Receptor

Research Areas:  

Endocrinology

11-Ketodihydrotestosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a Ki of 20.4 nM and an EC50 of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells .
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1
1 Cited Publications
Cat. No.: HY-130012
CAS No.: 1370363-74-8
Purity:  98.01%
Research Areas:  

Metabolic Disease

CO23 is a selective thyroid hormone receptor (TR) α agonist and used for growth and development regulation .
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1
1 Cited Publications
Cat. No.: HY-P0312
CAS No.: 2918768-02-0
Target:  

c-Myc

Research Areas:  

Cancer

c-Myc Peptide (TFA) is a synthetic peptide corresponding to the C-terminal amino acids (410-419) of human c-myc protein, and participates in regulation of growth-related gene transcription.
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1
1 Cited Publications
Cat. No.: HY-W016393
CAS No.: 2305-13-7
Dihydroconiferyl alcohol is a cell division factor. Dihydroconiferyl alcohol can be isolated from the American sycamore (Acer pseudoplatanus L.). Dihydroconiferyl alcohol inhibits the degradation of Indole-3-acetic acid (HY-18569). Dihydroconiferyl alcohol can stimulate the growth of soybean and tobacco callus tissue and synergistically enhance Indole-3-acetic acid-induced hypocotyl elongation in cucumber. Dihydroconiferyl alcohol can be used in the research of plant growth regulation .
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1
1 Cited Publications
Cat. No.: HY-145778
CAS No.: 2377492-26-5
Purity:  99.94%
AGI-41998 is a potent and orally active inhibitor of methionine adenosyltransferase 2A (MAT2A) that effectively penetrates the blood-brain barrier. AGI-41998 exhibits inhibitory activities against MAT2A and S-adenosyl methionine (SAM) in HCT-116 MTAP-null cells with IC50s of 22 nM and 34 nM. AGI-41998 can significantly inhibit the proliferation of HCT-116 cells and tumor growth. AGI-41998 can be used to study the role of SAM regulation in the central nervous system (CNS) and colon cancer .
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1
1 Cited Publications
Cat. No.: HY-113416R
CAS No.: 651-48-9
Synonyms: DHEA sulfate (Standard); Prasterone sulfate (Standard)
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) (Standard) is the analytical standard of Dehydroepiandrosterone sulfate (HY-113416). This product is intended for research and analytical applications. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
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1
1 Cited Publications
Cat. No.: HY-P70718
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T Cell growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In regulation Of T-Cell Clonal Expansion; TCGF; T-Cell growth Factor; Interleukin-2; Lymphokine
Species:  
Rat
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P7037AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T Cell growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In regulation Of T-Cell Clonal Expansion; TCGF; T-Cell growth Factor; Interleukin-2; Lymphokine
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P70646AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T Cell growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In regulation Of T-Cell Clonal Expansion; TCGF; T-Cell growth Factor; Interleukin-2; Lymphokine
Species:  
Mouse
Source:  
E. coli
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