Diniconazole
Based on 1 Customer Validation
Diniconazole (S-3308) is a newly developed fungicide. Diniconazole exhibits fungicidal activity against Bolrytis cintrca, Sordaria fumicola, Fusarium graminearum, Sclerotium cepivornm, and Bipolaris sorokiniana with IC50 values of 0.012, <0.001, 0.008, 0.02, and 0.06 mg/L, respectively. Diniconazole can be used in research related to the prevention and control of plant fungal diseases and plant growth regulation.
For research use only. We do not sell to patients.
- Purity: 98.23%
- CAS No.: 83657-24-3
- Formula: C15H17Cl2N3O
- Molecular Weight:326.22
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Diniconazole shows fungitoxic activity against Bolrytis cintrca, Sordaria fumicola, Fusarium graminearum, Sclerotium cepivornm and Bipolaris sorokiniana, with IC50 values of 0.012, <0.001, 0.008, 0.02 and 0.06 mg/L, respectively[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 83657-24-3
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Appearance Solid
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Molecular Weight 326.22
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Formula C15H17Cl2N3O
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Color White to off-white
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SMILES
OC(C(C)(C)C)/C(N1N=CN=C1)=C\C2=CC=C(Cl)C=C2Cl
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Synonyms
S-3308
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : ≥ 100 mg/mL (306.54 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (7.66 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (7.66 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (276 KB)
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SDS (596 KB)
- English - EN (596 KB)
- Français - FR (596 KB)
- Deutsch - DE (596 KB)
- Norwegian - NO (596 KB)
- Español - ES (596 KB)
- Swedish - SV (596 KB)
- Italian - IT (596 KB)
- Korean - KR (596 KB)
- Portuguese - PT (596 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.0654 mL | 15.3271 mL | 30.6542 mL | 76.6354 mL |
| 5 mM | 0.6131 mL | 3.0654 mL | 6.1308 mL | 15.3271 mL | |
| 10 mM | 0.3065 mL | 1.5327 mL | 3.0654 mL | 7.6635 mL | |
| 15 mM | 0.2044 mL | 1.0218 mL | 2.0436 mL | 5.1090 mL | |
| 20 mM | 0.1533 mL | 0.7664 mL | 1.5327 mL | 3.8318 mL | |
| 25 mM | 0.1226 mL | 0.6131 mL | 1.2262 mL | 3.0654 mL | |
| 30 mM | 0.1022 mL | 0.5109 mL | 1.0218 mL | 2.5545 mL | |
| 40 mM | 0.0766 mL | 0.3832 mL | 0.7664 mL | 1.9159 mL | |
| 50 mM | 0.0613 mL | 0.3065 mL | 0.6131 mL | 1.5327 mL | |
| 60 mM | 0.0511 mL | 0.2555 mL | 0.5109 mL | 1.2773 mL | |
| 80 mM | 0.0383 mL | 0.1916 mL | 0.3832 mL | 0.9579 mL | |
| 100 mM | 0.0307 mL | 0.1533 mL | 0.3065 mL | 0.7664 mL |
Diniconazole Related Classifications
HY-B1948 Related Classifications
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