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  4. Endosidin-2

Endosidin2 (ES2) binds to the exocyst component of 70 kDa (EXO70) subunit of the exocyst complex with a Kd of 253 μM. Endosidin2 inhibits exocytosis and endosomal recycling in both plant and human cells and enhances plant vacuolar trafficking. Endosidin2 is a valuable new tool for the study of exocytosis.

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Endosidin-2 Chemical Structure

Endosidin-2 Chemical Structure

CAS No. : 1839524-44-5

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10 mM * 1 mL in DMSO
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Based on 1 publication(s) in Google Scholar

Endosidin-2 Related Antibodies

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Description

Endosidin2 (ES2) binds to the exocyst component of 70 kDa (EXO70) subunit of the exocyst complex with a Kd of 253 μM. Endosidin2 inhibits exocytosis and endosomal recycling in both plant and human cells and enhances plant vacuolar trafficking. Endosidin2 is a valuable new tool for the study of exocytosis[1].

Clinical Trial
Molecular Weight

414.17

Formula

C15H12FIN2O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N/N=C/C1=CC(OC)=C(O)C(I)=C1)C2=CC=CC(F)=C2.[(E)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (241.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4145 mL 12.0723 mL 24.1447 mL
5 mM 0.4829 mL 2.4145 mL 4.8289 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4145 mL 12.0723 mL 24.1447 mL 60.3617 mL
5 mM 0.4829 mL 2.4145 mL 4.8289 mL 12.0723 mL
10 mM 0.2414 mL 1.2072 mL 2.4145 mL 6.0362 mL
15 mM 0.1610 mL 0.8048 mL 1.6096 mL 4.0241 mL
20 mM 0.1207 mL 0.6036 mL 1.2072 mL 3.0181 mL
25 mM 0.0966 mL 0.4829 mL 0.9658 mL 2.4145 mL
30 mM 0.0805 mL 0.4024 mL 0.8048 mL 2.0121 mL
40 mM 0.0604 mL 0.3018 mL 0.6036 mL 1.5090 mL
50 mM 0.0483 mL 0.2414 mL 0.4829 mL 1.2072 mL
60 mM 0.0402 mL 0.2012 mL 0.4024 mL 1.0060 mL
80 mM 0.0302 mL 0.1509 mL 0.3018 mL 0.7545 mL
100 mM 0.0241 mL 0.1207 mL 0.2414 mL 0.6036 mL
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Endosidin-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Endosidin-21839524-44-5ES2Endosidin2Endosidin 2ES 2ES-2OthersInhibitorinhibitorinhibit

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