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hydrolysis product

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Acyltransferase (1) Adrenergic Receptor (1) Akt (1) Amylases (2) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (5) Apoptosis (6) Bacterial (5) Bcl-2 Family (1) Beta-lactamase (2) Biochemical Assay Reagents (16) Carboxypeptidase (1) Cathepsin (1) Cholinesterase (ChE) (2) COX (1) CXCR (1) DAGL (1) Dengue Virus (1) DNA/RNA Synthesis (2) Drug Derivative (5) Drug Intermediate (2) Drug Isomer (1) Drug Metabolite (16) EGFR (1) Endogenous Metabolite (17) Environmental Pollutants (3) Estrogen Receptor/ERR (1) Eukaryotic Initiation Factor (eIF) (1) Flavivirus (1) Fluorescent Dye (15) IFNAR (1) Insecticide (2) Integrin (1) Interleukin Related (3) Isotope-Labeled Compounds (1) mAChR (2) MAGL (1) mGluR (3) NF-κB (1) NO Synthase (1) Nucleoside Antimetabolite/Analog (1) P2Y Receptor (1) p38 MAPK (2) Parasite (6) Phosphatase (1) Phosphodiesterase (PDE) (6) Phospholipase (1) PKC (2) Polo-like Kinase (PLK) (1) Prostaglandin Receptor (2) PROTACs (1) Reactive Oxygen Species (ROS) (1) Reference Standards (40) STAT (1) TNF Receptor (2) Toll-like Receptor (TLR) (1) Topoisomerase (1)
By Research Areas:	Cancer (22) Cardiovascular Disease (7) Endocrinology (6) Infection (17) Inflammation/Immunology (15) Metabolic Disease (17) Neurological Disease (17)
Click Chemistry:	PROTAC Synthesis (1)

118

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B2193

α-Amylase 2 Publications Verification	Environmental Pollutants Amylases	Others
α-Amylase is a hydrolase enzyme that catalyses the hydrolysis of internal α-1, 4-glycosidic linkages in starch to yield products like glucose and maltose.

HY-W723152

Poly(D,L-lactide-co-glycolide)	Drug Intermediate	Inflammation/Immunology
Poly(D,L-lactide-co-glycolide) is a biodegradable polymer copolymer. Poly(D,L-lactide-co-glycolide) undergoes degradation through ester bond hydrolysis into lactic acid and glycolic acid. These two products can be naturally eliminated through metabolism in the body (such as the tricarboxylic acid cycle), without the risk of long-term accumulation. Poly(D,L-lactide-co-glycolide) can be used in medical sutures, implants, and drug delivery systems .

HY-126404

Casein hydrolysate	Environmental Pollutants Interleukin Related Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Casein hydrolysate is an orally effective, multi-functional mixture of bioactive peptides, a hydrolysis product of casein (HY-125865), containing ACE inhibitors and immunomodulatory target regulators, among others. Casein hydrolysate releases short-chain bioactive peptides through enzymatic hydrolysis of casein, increasing cellular glutathione and catalase levels, enhancing ConA-induced IL-2 production, and exhibiting metal ion chelation, free radical scavenging, antibacterial, and mineral absorption-promoting effects. Casein hydrolysate lowers blood pressure by inhibiting angiotensin-converting enzyme (ACE) and reducing bradykinin degradation .

HY-P2968

Bacterial α-Amylase	Amylases	Others
Bacterial α-Amylase catalyses the hydrolysis of internal α-1,4-glycosidic linkages in starch in low molecular weight products, such glucose, maltose and maltotriose units. Bacterial α-Amylase is often used in biochemical studies .

HY-D2869

Ac-H-FluNox	Fluorescent Dye Drug Intermediate	Others
Ac-H-FluNox is an acetylated cell-compatible prodrug of H-FluNox (HY-D2339). Ac-H-FluNox undergoes intracellular hydrolysis of its acetyl group by esterases to generate H-FluNox, which then undergoes a deoxygenation reaction with labile heme to form a fluorescent product. Ac-H-FluNox detects fluctuations of labile heme in living cells, acute labile heme release upon nitric oxide stimulation, and accumulation of labile heme following inhibition of heme export proteins .

HY-138877

Phosphoglycolic acid	Endogenous Metabolite	Infection
Phosphoglycolic acid is a metabolite and a bacterial cytoplasmic component. Phosphoglycolic acid acts as a by-product generated during the preparation of phosphoglycolohydroxamic acid via hydrolysis of ethyl phosphoglycolate. Phosphoglycolic acid also functions as an active component of postbiotics .

HY-129043

3-Formyl rifamycin	Drug Metabolite	Infection
3-Formyl rifamycin is an acid degradation product of the broad-spectrum antibiotic Rifampicin (HY-B0272). 3-Formyl rifamycin forms via acid hydrolysis of Rifampicin in an acidic environment .

HY-137135A

Cantharidic acid disodium	Phosphatase Apoptosis	Cancer
Cantharidic acid disodium is the hydrolysis product of the acid anhydride Cantharidin that induces apoptosis in various human cancer cells. Cantharidic acid disodium is a selective protein phosphatase 2 (PP2A) and PP1 inhibitor withIC₅₀ values of 50 nM and 600 nM, respectively .

HY-160973

ELF97 phosphate ELFP	Biochemical Assay Reagents	Others
ELF97 phosphate (ELFP) is a phosphatase substrate, which can produced a fluorescent, water-insoluble product ELF97 alcohol after hydrolysis by phosphatases. ELF97 phosphate can be utilized to study and quantify the activity of extracellular phosphatases of algae in natural water .

HY-76476

(S)-Tetrahydrofuran-3-ol (+)-3-Hydroxytetrahydrofuran	Biochemical Assay Reagents	Others
(S)-Tetrahydrofuran-3-ol is a (S)-enantiomer of Tetrahydrofuran-3-ol. Tetrahydrofuran-3-ol is an important precursor for the production of HIV protease inhibitors. Tetrahydrofuran-3-ol can be produced via chemical synthesis or by enzymatic hydrolysis of bulkier esters and inversion of the unwanted product .

HY-B2193A

α-Amylase, Human Saliva 1,4-alpha-D-Glucan-glucanohydrolase, ptyalin	Biochemical Assay Reagents	Metabolic Disease Inflammation/Immunology
α-Amylase, Human Saliva (1,4-alpha-D-Glucan-glucanohydrolase) is a hydrolase enzyme that can be isolated from human saliva. α-Amylase, Human Saliva catalyses the hydrolysis of internal α-1, 4-glycosidic linkages in starch to yield products like glucose and maltose. α-Amylase, Human Saliva can be used in life science research .

HY-B2193C

α-Amylase, Porcine Pancreatic 1,4-alpha-D-Glucan-glucanohydrolase, amy2, PPA, PA	Biochemical Assay Reagents	Others
α-Amylase, Porcine Pancreatic (1,4-alpha-D-Glucan-glucanohydrolase) is a hydrolase enzyme that can be isolated from porcine pancreatic. α-Amylase, Porcine Pancreatic catalyses the hydrolysis of internal α-1, 4-glycosidic linkages in starch to yield products like glucose and maltose. α-Amylase, Porcine Pancreatic can be used in life science research .

HY-W145498

D-(+)-Cellotetraose Cellotetraose	Drug Metabolite	Others
D-(+)-Cellotetraose (Cellotetraose) is a primary hydrolysis product of cellulose .

HY-113441

4-Hydroxy-3-methoxyphenylglycol sulfate potassium MHPG sulfate potassium	Biochemical Assay Reagents	Others
4-Hydroxy-3-methoxyphenylglycol sulfate potassium is a biosynthesis product that releases Na₂SO₄ and free ethylene glycol on acidic hydrolysis .

HY-P4417

Ac-IEPD-AMC	Fluorescent Dye	Others
Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-171213

NB-3	Toll-like Receptor (TLR)	Neurological Disease
NB-3 is a nicotinamide adenine dinucleotide (NAD) hydrolase SARM1 inhibitor. NB-3 intercepts NAD hydrolysis and undergoes covalent conjugation with the reaction product adenosine diphosphate ribose (ADPR). The resulting small-molecule ADPR adducts are highly potent and confer compelling neuroprotection in neurological injury .

HY-P4419A

Boc-Asp(OBzl)-Pro-Arg-AMC acetate	Fluorescent Dye	Others
Boc-Asp(OBzl)-Pro-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC acetate undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-B0593R

Ceftazidime (Standard) GR20263 (Standard)	Beta-lactamase Reference Standards Bacterial Antibiotic	Infection
Ceftazidime (Standard) is the analytical standard of Ceftazidime. This product is intended for research and analytical applications. Ceftazidime (GR20263), an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases .

HY-B0593AR

Ceftazidime pentahydrate (Standard) GR20263 pentahydrate (Standard)	Beta-lactamase Reference Standards Bacterial Antibiotic	Infection Cancer
Ceftazidime (pentahydrate) (Standard) is the analytical standard of Ceftazidime (pentahydrate). This product is intended for research and analytical applications. Ceftazidime (GR20263) pentahydrate , an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases .

HY-B2193B

α-Amylase, Human Pancreas Amylase, a-Amylase, 1,4-a-D-glucan glucanohydrolase, glycogenase	Biochemical Assay Reagents	Others
α-Amylase, Human Pancreas (Amylase) is a hydrolase enzyme that can be isolated from human pancreas. α-Amylase, Human Pancreas catalyses the hydrolysis of internal α-1, 4-glycosidic linkages in starch to yield products like glucose and maltose. α-Amylase, Human Pancreas can be used in life science research .

HY-W007077

(2-Amino-5-bromophenyl)(pyridin-2-yl)methanone	Drug Metabolite	Neurological Disease
(2-Amino-5-bromophenyl)(pyridin-2-yl)methanone is a precursor in the synthesis of benzodiazepines and is also a hydrolysis product of Clonazepam.

HY-P4406

Abz-AGLA-Nba 1 Publications Verification	Fluorescent Dye	Others
Abz-AGLA-Nba is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal .

HY-W011297

Methyl arachidonate Arachidonic acid methyl ester	PKC	Metabolic Disease
Methyl arachidonate is a protein kinase C activator and also an orally active substrate that undergoes esterase-mediated hydrolysis. Methyl arachidonate indirectly activates protein kinase C via eicosanoid metabolites generated through the arachidonic acid metabolic pathway, exerting effects via cyclooxygenase products at low concentrations and via lipoxygenase products at high concentrations. Methyl arachidonate can be used in studies related to lipodystrophy .

HY-143678

Citrulline-specific probe-biotin	Biochemical Assay Reagents	Others
Citrulline-specific probe-biotin is a biotinylated probe for detection of citrulline. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-biotin is a biological probe that can identify diseases showing abnormal increases in PAD activity .

HY-15249R

JZL 184 (Standard)	MAGL Reference Standards	Neurological Disease
JZL 184 (Standard) is the analytical standard of JZL 184. This product is intended for research and analytical applications. JZL 184 is a potent, selective and irreversible MAGL inhibitor that blocks 2-Arachidonoylglycerol (2-AG) hydrolysis in brain membranes (IC50 of 8 nM). JZL 184 displays >300-fold selectivity for MAGL over FAAH .

HY-125774

Bimatoprost acid 17-Phenyl trinor PGF2α	Prostaglandin Receptor	Others
Bimatoprost acid (17-Phenyl trinor PGF2α), the acid hydrolysis product of Bimatoprost (HY-B0191), is a potent agonist of prostaglandin FP receptor .

HY-137252

22,23-Dihydroavermectin B1a aglycon Ivermectin Impurity G	Parasite	Infection
22,23-Dihydroavermectin B1a aglycon is an acid degradation product produced by hydrolysis of the disaccharide unit of ivermectin. It can inhibit nematode larval development, but does not cause paralytic activity.

HY-W717548

Safinamide acid	Drug Metabolite	Others
Safinamide acid (Compound Imp-E) is the metabolite of Safinamide (HY-70057). Safinamide acid can be formed by hydrolysis of Safinamide intermediate under alkaline or acidic conditions. Safinamide acid is utilized to monitor process-related impurities and degradation products in safinamide samples .

HY-P4417A

Ac-IEPD-AMC TFA	Fluorescent Dye	Others
Ac-IEPD-AMC TFA is a fluorescent substrate used to measure protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC fluoresces under UV light irradiation and can emit fluorescent signals .

HY-P4323A

Boc-Gln-Arg-Arg-AMC acetate	Fluorescent Dye	Others
Boc-Gln-Arg-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-W329357

15:0 Lyso PC 1 Publications Verification	Endogenous Metabolite	Cardiovascular Disease
15:0 Lyso PC is a lysophosphatidylcholine (Lyso PC), a product of phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine (PC) and is involved in cell membrane remodeling and inflammatory signaling. 15:0 Lyso PC demonstrates significant lipid metabolism disturbances in the serum with ischemic heart disease (IHD) and ischemic cardiomyopathy (ICM). 15:0 Lyso PC can be used as a lipid biomarker for cardiovascular disease .

HY-D1377

Citrulline-specific probe-rhodamine hydrate	Fluorescent Dye	Others
Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis .

HY-135000

Decarbamoylsaxitoxin DcSTX; DecarbamoylSTX	Endogenous Metabolite Drug Metabolite	Neurological Disease
Decarbamoylsaxitoxin is a sodium channel inhibitor that blocks the influx of sodium ions through the membranes of excitable nerves and skeletal muscle cells, thereby preventing the formation of action potentials. Decarbamoylsaxitoxin is an acidic hydrolysis product of saxitoxin, and its toxic effects on mice are identical to those of saxitoxin. Decarbamoylsaxitoxin inhibits veratridine- and ouabain-induced swelling and lysis of mouse neuroblastoma cells by blocking Na ⁺ channels. Decarbamoylsaxitoxin can be used in studies related to paralytic shellfish poisoning .

HY-W714675

Glucoiberin	Endogenous Metabolite	Cancer
Glucoiberin is a glucosinolate found in Brassica oleracea. Hydrolysis products of Glucoiberin exhibit anticancer activity .

HY-156752

Cyclosiversioside F 16,25-diacetate	Drug Metabolite	Others
Cyclosiversioside F 16,25-diacetate (Compound 6), a glycoside, is an alkaline hydrolysis product of Acetyl Derivative (Compound 2) .

HY-N6730

Hydrolyzed Fumonisin B1 Aminopentol	Apoptosis	Neurological Disease
Hydrolyzed Fumonisin B1 (Aminopentol) is the backbone and main hydrolysis product of the mycotoxin Fumonisin B1 (HY-N6719). Hydrolyzed Fumonisin B1 can weakly inhibit ceramide synthase .

HY-P4406A

Abz-AGLA-Nba TFA	Fluorescent Dye	Others
Abz-AGLA-Nba TFA is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba TFA is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal .

HY-W010378R

D-Asparagine (Standard) H-D-Asn-OH (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
D-Asparagine (Standard) (H-D-Asn-OH (Standard)) is the analytical standard of D-Asparagine (HY-W010378). This product is intended for research and analytical applications. D-Asparagine (H-D-Asn-OH) is a competitive inhibitor of L-Asparagine hydrolysis with a K_i value of 0.24 mM. D-Asparagine is a source of nitrogen for yeast strains. D-Asparagine is a good substrate for the external yeast asparaginase but is a poor substrate for the internal enzyme.

HY-100788R

2-PMPA (Standard) 2-(Phosphonomethyl)pentanedioic acid (Standard)	Reference Standards Carboxypeptidase	Neurological Disease
2-PMPA (2-(Phosphonomethyl)pentanedioic acid) Standard is the analytical standard of 2-PMPA (HY-100788). This product is intended for research and analytical applications. 2-PMPA (2-(Phosphonomethyl)pentanedioic acid) sodium is a glutamate carboxypeptidase II (GCPII) inhibitor with an IC₅₀ of 0.0003 μM. 2-PMPA sodium shows low blood-brain barrier penetration. 2-PMPA sodium blocks the hydrolysis of NAAG, regulates glutamate levels in the brain and neurovascular coupling. 2-PMPA sodium is applicable to the research of neurological diseases.

HY-N12146

Spinosyn D 17-pseudoaglycone	Parasite	Infection
Spinosyn D 17-pseudoaglycone is a hydrolysis product of the minor insecticide component Spinosyn D (HY-125326) .

HY-77195

Poloxime	Polo-like Kinase (PLK)	Cancer
Poloxime, a hydrolysis product of poloxin, is a non-ATP-competitive Plk1 inhibitor, with moderate Plk1 inhibitory activity.

HY-W705140A

Monohydroxy melphalan hydrochloride Hydroxymelphalan hydrochloride	Drug Metabolite	Cancer
Monohydroxy melphalan hydrochloride (Hydroxymelphalan hydrochloride) is a degradation product of Melphalan (HY-17575), obtained through the hydrolysis of Melphalan in aqueous solutions (including cell culture media and human plasma) .

HY-W104076

2-Amino-2'-fluoro-5-nitrobenzophenone	Drug Metabolite	Others
2-Amino-2'-fluoro-5-nitrobenzophenone is a precursor in the synthesis of benzodiazepines. 2-Amino-2'-fluoro-5-nitrobenzophenone is also an acid hydrolysis product of Flunitrazepam.

HY-W011596

2-Amino-2'-chloro-5-nitrobenzophenone	Drug Metabolite	Neurological Disease
2-Amino-2'-chloro-5-nitrobenzophenone is a precursor in the synthesis of benzodiazepines. 1 2-Amino-2’-chloro-5-nitrobenzophenone is also a hydrolysis product of Clonazepam.

HY-137798

Chromozym PL	Fluorescent Dye	Others
Chromozym PL is a chromogenic substrate for plasmin, and the enzymatic reaction can be carried out in 0.1mL Tris-HCl buffer (50 mM, pH 7.8). 100 μM Chromozym PL was dissolved and prepared. After adding the hydrolase, the generation of p-nitroaniline (pNA) at 405 nm was continuously observed, and the hydrolysis products were calculated .

HY-E70217

Uracil DNA Glycosylase (UDG/UNG), heat-sensitive Heat-sensitive UDG	DNA/RNA Synthesis	Cancer
Uracil DNA Glycosylase (UDG/UNG), heat-sensitive (Heat-sensitive UDG) can catalyze the hydrolysis of the N-glycosidic bond between the uracil base and the sugar phosphate backbone in the DNA chain containing uracil, releasing free uracil. Uracil DNA Glycosylase (UDG/UNG), heat-sensitive eliminates the carryover contamination dUTP-incorporated amplification products .

HY-171015

10-(Phosphonooxy)-1-decanole HDP	Biochemical Assay Reagents	Others
10-(Phosphonooxy)-1-decanole (10-Hydroxydecyl dihydrogen phosphate) is a hydrolysis product of 10-Methacryloyloxydecyl dihydrogen phosphate .

HY-164949

Ribociclib acetate	Drug Metabolite	Cancer
Ribociclib acetate is a degradation product of Ribociclib (HY-15777) under acid-base hydrolysis conditions. Ribociclib acetate has been predicted to be carcinogenic .

HY-N13105

Camelliagenin A 16-tiglate	Others	Others
Camelliagenin A 16-tiglate (compound 6) is a camellia saponin isolated from the acid hydrolysis product of Harpullia cupanioides Roxb root bark saponin .

HY-N6731

Hydrolyzed Fumonisin B2	Others	Infection
Hydrolyzed Fumonisin B2 (HFB2) is a hydrolysis product of fumonisins (HF), which retains biological activity. Hydrolyzed Fumonisin B2 (HFB2) exhibits phytotoxicity .

Cat. No.	Product Name	Type

HY-D2869

Ac-H-FluNox

Fluorescent Dyes

Ac-H-FluNox is an acetylated cell-compatible prodrug of H-FluNox (HY-D2339). Ac-H-FluNox undergoes intracellular hydrolysis of its acetyl group by esterases to generate H-FluNox, which then undergoes a deoxygenation reaction with labile heme to form a fluorescent product. Ac-H-FluNox detects fluctuations of labile heme in living cells, acute labile heme release upon nitric oxide stimulation, and accumulation of labile heme following inhibition of heme export proteins .

HY-D1377

Citrulline-specific probe-rhodamine hydrate

Fluorescent Dyes

Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis .

HY-D1687

Flubi-2	Fluorescent Dyes
Flubi-2 is a fluorescein-biotin based pH-ratio dye (Ex=480 nm, Em= 520-560 nm) with a pK value of 6.7. Flubi-2 is a hydrolysis product of Flubida-2 (non-fluorescent, membrane permeable). Flubi-2 can be used for pH determination of organelles of the secretory pathway (such as golgi apparatus and endoplasmic reticulum) in living cells .

Cat. No.	Product Name	Type

HY-138877

Phosphoglycolic acid	Biochemical Assay Reagents
Phosphoglycolic acid is a metabolite and a bacterial cytoplasmic component. Phosphoglycolic acid acts as a by-product generated during the preparation of phosphoglycolohydroxamic acid via hydrolysis of ethyl phosphoglycolate. Phosphoglycolic acid also functions as an active component of postbiotics .

HY-112624H

Dextran T2 (MW 2,000)

Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)

Biochemical Assay Reagents

Dextran T2 (Dextran 2; Dextran T2(MW 1600-2400)) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM₂), and Isomaltotriose (IM₃). Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity .

HY-76476

(S)-Tetrahydrofuran-3-ol (+)-3-Hydroxytetrahydrofuran	Biochemical Assay Reagents
(S)-Tetrahydrofuran-3-ol is a (S)-enantiomer of Tetrahydrofuran-3-ol. Tetrahydrofuran-3-ol is an important precursor for the production of HIV protease inhibitors. Tetrahydrofuran-3-ol can be produced via chemical synthesis or by enzymatic hydrolysis of bulkier esters and inversion of the unwanted product .

HY-W329357

15:0 Lyso PC

1 Publications Verification

Biochemical Assay Reagents

15:0 Lyso PC is a lysophosphatidylcholine (Lyso PC), a product of phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine (PC) and is involved in cell membrane remodeling and inflammatory signaling. 15:0 Lyso PC demonstrates significant lipid metabolism disturbances in the serum with ischemic heart disease (IHD) and ischemic cardiomyopathy (ICM). 15:0 Lyso PC can be used as a lipid biomarker for cardiovascular disease .

HY-Y1766R

2,3,4-Trimethoxybenzaldehyde (Standard)	Biochemical Assay Reagents
2,3,4-Trimethoxybenzaldehyde (Standard) is the analytical standard of 2,3,4-Trimethoxybenzaldehyde. This product is intended for research and analytical applications. 2,3,4-Trimethoxybenzaldehyde (2,3,4-Trihydrooxy Benzaldehyde) can be used to study the effects on tubulin-dependent GTP hydrolysis .

HY-76476R

(S)-Tetrahydrofuran-3-ol (Standard)

(+)-3-Hydroxytetrahydrofuran (Standard)

Biochemical Assay Reagents

(S)-Tetrahydrofuran-3-ol (Standard) is the analytical standard of (S)-Tetrahydrofuran-3-ol. This product is intended for research and analytical applications. (S)-Tetrahydrofuran-3-ol is a (S)-enantiomer of Tetrahydrofuran-3-ol. Tetrahydrofuran-3-ol is an important precursor for the production of HIV protease inhibitors. Tetrahydrofuran-3-ol can be produced via chemical synthesis or by enzymatic hydrolysis of bulkier esters and inversion of the unwanted product .

Cat. No.	Product Name	Target	Research Area

HY-P4417

Ac-IEPD-AMC	Fluorescent Dye	Others
Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-P4419A

Boc-Asp(OBzl)-Pro-Arg-AMC acetate	Fluorescent Dye	Others
Boc-Asp(OBzl)-Pro-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC acetate undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-P4846

Ac-Pro-Gly-Pro-OH 2 Publications Verification	CXCR Apoptosis IFNAR TNF Receptor Interleukin Related	Infection Inflammation/Immunology
Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and acts as a CXCR2 agonist . Ac-Pro-Gly-Pro-OH exerts bactericidal activity by generating hydrogen peroxide, inhibits pulmonary inflammation, and reduces immune cell apoptosis (apoptosis). Ac-Pro-Gly-Pro-OH promotes the production of IFN-γ and inhibits the production of TNF-α and IL-6 in leukocytes. Ac-Pro-Gly-Pro-OH increases the survival rate of mice in sepsis models, enhances the bactericidal activity of neutrophils, acts as a neutrophil chemoattractant, induces neutrophil polarization, and regulates inflammatory and repair processes. Ac-Pro-Gly-Pro-OH induces chronic inflammation and tissue remodeling through sustained action. Ac-Pro-Gly-Pro-OH is released via alkaline hydrolysis of corneal proteins in alkali-injured eyes, thereby driving the early infiltration of neutrophils into the cornea. Ac-Pro-Gly-Pro-OH is applicable to research related to sepsis, chronic obstructive pulmonary disease, cystic fibrosis, bronchiolitis obliterans syndrome, severe asthma, idiopathic pulmonary fibrosis, and corneal ulcer .

HY-P4406

Abz-AGLA-Nba 1 Publications Verification	Fluorescent Dye	Others
Abz-AGLA-Nba is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal .

HY-P4417A

Ac-IEPD-AMC TFA	Fluorescent Dye	Others
Ac-IEPD-AMC TFA is a fluorescent substrate used to measure protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC fluoresces under UV light irradiation and can emit fluorescent signals .

HY-P4323A

Boc-Gln-Arg-Arg-AMC acetate	Fluorescent Dye	Others
Boc-Gln-Arg-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-P4406A

Abz-AGLA-Nba TFA	Fluorescent Dye	Others
Abz-AGLA-Nba TFA is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba TFA is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal .

HY-137798

Chromozym PL	Fluorescent Dye	Others
Chromozym PL is a chromogenic substrate for plasmin, and the enzymatic reaction can be carried out in 0.1mL Tris-HCl buffer (50 mM, pH 7.8). 100 μM Chromozym PL was dissolved and prepared. After adding the hydrolase, the generation of p-nitroaniline (pNA) at 405 nm was continuously observed, and the hydrolysis products were calculated .

HY-P4465

Gly-Arg-pNA	Fluorescent Dye	Others
Gly-Arg-pNA is a fluorogenic substrate for the measurement of protease activity. Gly-Arg-pNA undergoes hydrolysis and releases the fluorescent product p-nitroaniline. p-nitroaniline is in a fluorescent state under ultraviolet light irradiation and can emit a fluorescent signal .

HY-P4419

Boc-Asp(OBzl)-Pro-Arg-AMC	Fluorescent Dye	Others
Boc-Asp(OBzl)-Pro-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). The excitation and emission wavelengths are 351 nm and 430 nm, respectively .

HY-P4408

Ac-Arg-Gly-Lys-AMC	Fluorescent Dye	Others
Ac-Arg-Gly-Lys-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Arg-Gly-Lys-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-P4323

Boc-Gln-Arg-Arg-AMC	Fluorescent Dye	Others
Boc-Gln-Arg-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-P4416

Ac-Gly-Ala-Lys(Ac)-AMC	Fluorescent Dye	Others
Ac-Gly-Ala-Lys(Ac)-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Gly-Ala-Lys(Ac)-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-P4404

Abz-GIVRAK(Dnp)	Cathepsin	Others
Abz-GIVRAK(Dnp) is the most efficient substrate for cathepsin B and is highly selective for this enzyme among lysosomal cysteine proteases. After Abz-GIVRAK(Dnp) is hydrolyzed, aminoacylbenziminosulfosuccinic acid (Abz-SAS) is released, and dinitrobenzoyl (Dnp) is also released. The product of this hydrolysis reaction, Abz-SAS, is fluorescent under ultraviolet light and can emit a fluorescent signal .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B2193

α-Amylase 2 Publications Verification	Structural Classification Natural Products Microorganisms Classification of Application Fields Other Diseases Disease Research Fields Source Classification	Environmental Pollutants Amylases
α-Amylase is a hydrolase enzyme that catalyses the hydrolysis of internal α-1, 4-glycosidic linkages in starch to yield products like glucose and maltose.

HY-W145498

D-(+)-Cellotetraose Cellotetraose	Structural Classification Polysaccharides Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Saccharides Source Classification	Drug Metabolite
D-(+)-Cellotetraose (Cellotetraose) is a primary hydrolysis product of cellulose .

HY-135000

Decarbamoylsaxitoxin DcSTX; DecarbamoylSTX	Structural Classification Natural Products Microorganisms Source Classification	Endogenous Metabolite Drug Metabolite
Decarbamoylsaxitoxin is a sodium channel inhibitor that blocks the influx of sodium ions through the membranes of excitable nerves and skeletal muscle cells, thereby preventing the formation of action potentials. Decarbamoylsaxitoxin is an acidic hydrolysis product of saxitoxin, and its toxic effects on mice are identical to those of saxitoxin. Decarbamoylsaxitoxin inhibits veratridine- and ouabain-induced swelling and lysis of mouse neuroblastoma cells by blocking Na ⁺ channels. Decarbamoylsaxitoxin can be used in studies related to paralytic shellfish poisoning .

HY-W714675

Glucoiberin	Structural Classification Iberis amara L. Plants Brassicaceae Saccharides Monosaccharides Source Classification	Endogenous Metabolite
Glucoiberin is a glucosinolate found in Brassica oleracea. Hydrolysis products of Glucoiberin exhibit anticancer activity .

HY-N6730

Hydrolyzed Fumonisin B1 Aminopentol	Natural Products Microorganisms Source Classification	Apoptosis
Hydrolyzed Fumonisin B1 (Aminopentol) is the backbone and main hydrolysis product of the mycotoxin Fumonisin B1 (HY-N6719). Hydrolyzed Fumonisin B1 can weakly inhibit ceramide synthase .

HY-N12146

Spinosyn D 17-pseudoaglycone	Natural Products Microorganisms Source Classification	Parasite
Spinosyn D 17-pseudoaglycone is a hydrolysis product of the minor insecticide component Spinosyn D (HY-125326) .

HY-N13105

Camelliagenin A 16-tiglate	Triterpenes Terpenoids Sapindaceae Plants Harpullia cupanioides Roxb. Source Classification	Others
Camelliagenin A 16-tiglate (compound 6) is a camellia saponin isolated from the acid hydrolysis product of Harpullia cupanioides Roxb root bark saponin .

HY-N6731

Hydrolyzed Fumonisin B2	Infection Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Others
Hydrolyzed Fumonisin B2 (HFB2) is a hydrolysis product of fumonisins (HF), which retains biological activity. Hydrolyzed Fumonisin B2 (HFB2) exhibits phytotoxicity .

HY-N0872R

Isosteviol (Standard) (-)-Isosteviol (Standard); iso-Steviol (Standard)	Structural Classification other families Terpenoids Diterpenoids Plants Source Classification	Interleukin Related Reference Standards Reactive Oxygen Species (ROS) Topoisomerase
Isosteviol (Standard) is the analytical standard of Isosteviol. This product is intended for research and analytical applications. Isosteviol ((-)-Isosteviol) is a derivative of Stevioside through acid catalyzed hydrolysis of Stevioside. Isosteviol inhibits DNA polymerase and DNA topoisomerase and has antibacterial, anticancer and anti-tuberculosis effects .

HY-129099AR

N-Desmethyltamoxifen hydrochloride (Standard)	Structural Classification Alkaloids Other Alkaloids Endogenous metabolite Source Classification	Reference Standards PKC Estrogen Receptor/ERR Drug Metabolite Endogenous Metabolite
N-Desmethyltamoxifen (hydrochloride) (Standard) is the analytical standard of N-Desmethyltamoxifen (hydrochloride). This product is intended for research and analytical applications. N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation[1][2][3].

HY-100196AR

Pyrroloquinoline quinone disodium salt (Standard) PQQ disodium salt (Standard); Methoxatin disodium salt (Standard)	Quinones Structural Classification Microorganisms Benzene Quinones Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Triazophos (Standard) is the analytical standard of Triazophos. This product is intended for research and analytical applications. Triazophos, a non-systemic insecticide and acaricide that acts as an acetylcholinesterase (AChE) inhibitor, covalently and irreversibly binds to the acetylcholine binding site, thus blocking the hydrolysis of acetylcholine and leading to hyperexcitability; it is effective against a variety of soil insects and mites, including aphids, thrips, midges, beetles, Lepidoptera larvae, cutworms, and spider mites in crops such as ornamentals, cotton, rice, maize, soybeans, oil palms, olives, and coffee.

HY-N13115A

Protoescigenin 21-tiglate (E)-21-Angeloyl-protoaescigenin	Aesculus chinensis Bunge Triterpenes Terpenoids Hippocastanaceae Plants Source Classification	Others
Protoescigenin 21-tiglate (compound 10) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. However, the antitumor activity of Protoescigenin 21-tiglate is relatively weak, with IC50 values of >80 μM and 80 μM against MCF-7 and HeLa cells, respectively .

HY-N13115

21-Angeloyl-protoaescigenin (Z)-Protoescigenin 21-tiglate	Aesculus chinensis Bunge Triterpenes Terpenoids Hippocastanaceae Plants Source Classification	Others
21-Angeloyl-protoaescigenin (compound 11) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. Protoescigenin 21-tiglate has antitumor activity, with IC50 values of 38.2 μM and 33 μM against MCF-7 and HeLa cells, respectively .

HY-N3018R

Isomaltose (Standard) 6-O-α-D-Glucopyranosyl-D-glucose (Standard); D-Isomaltose (Standard)	Structural Classification Human Gut Microbiota Metabolites Polysaccharides Microorganisms Endogenous metabolite Saccharides Source Classification	Reference Standards Endogenous Metabolite Parasite
Isomaltose (Standard) is the analytical standard of Isomaltose (HY-N3018). This product is intended for research and analytical applications. Isomaltose induces G-CSF secretion via heat-induced oxidative polymerization of glucose groups into high-molecular-weight compounds. Isomaltose modulates cecal bacterial cluster structure in mice. Isomaltose exhibits low glycemic index, slow hydrolysis, and prebiotic properties. Isomaltose reduces in vivo Cryptosporidium parvum colonization in neonatal mice. Isomaltose can be used for the research of Cryptosporidium parvum infection .

HY-B0442CR

Vardenafil dihydrochloride (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Phosphodiesterase (PDE)
Vardenafil (dihydrochloride) (Standard) is the analytical standard of Vardenafil (dihydrochloride). This product is intended for research and analytical applications. Vardenafil dihydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil dihydrochloride shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM respectively, while IC50s are >1000 nM for PDE3 and PDE4. Vardenafil dihydrochloride competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil dihydrochloride can be used for the research of erectile dysfunction, hepatitis, diabetes - .

HY-B0442AR

Vardenafil hydrochloride (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Phosphodiesterase (PDE) Endogenous Metabolite Reference Standards
Vardenafil (hydrochloride) (Standard) is the analytical standard of Vardenafil (hydrochloride). This product is intended for research and analytical applications. Vardenafil hydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil hydrochloride shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4 . Vardenafil hydrochloride competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels . Vardenafil hydrochloride can be used for the research of erectile dysfunction, hepatitis, diabetes - .

HY-B0442R

Vardenafil (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Phosphodiesterase (PDE) Endogenous Metabolite
Vardenafil (Standard) is the analytical standard of Vardenafil. This product is intended for research and analytical applications. Vardenafil is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC₅₀ of 0.7 nM. Vardenafil shows inhibitory towards PDE1, PDE6 with IC₅₀s of 180 nM, and 11 nM, while IC₅₀s are >1000 nM for PDE3 and PDE4 . Vardenafil competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels . Vardenafil can be used for the research of erectile dysfunction, hepatitis, diabetes ^[1]-[6].

HY-W049735R

N,N,O-Tridesmethylvenlafaxine (Standard)	Monophenols Phenols Endogenous metabolite Source Classification	Drug Metabolite Reference Standards Endogenous Metabolite
Vardenafil (dihydrochloride) (Standard) is the analytical standard of Vardenafil (dihydrochloride). This product is intended for research and analytical applications. Vardenafil dihydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil dihydrochloride shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM respectively, while IC50s are >1000 nM for PDE3 and PDE4. Vardenafil dihydrochloride competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil dihydrochloride can be used for the research of erectile dysfunction, hepatitis, diabetes - .

HY-B0442BR

Vardenafil hydrochloride trihydrate (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Phosphodiesterase (PDE)
Vardenafil (hydrochloride trihydrate) (Standard) is the analytical standard of Vardenafil (hydrochloride trihydrate). This product is intended for research and analytical applications. Vardenafil hydrochloride trihydrate is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil hydrochloride trihydrate shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4 . Vardenafil hydrochloride trihydrate competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels . Vardenafil hydrochloride trihydrate can be used for the research of erectile dysfunction, hepatitis, diabetes - .

HY-18252R

Avanafil (Standard) TA1790 (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Phosphodiesterase (PDE) NO Synthase Endogenous Metabolite
Avanafil (Standard) is the analytical standard of Avanafil. This product is intended for research and analytical applications. Avanafil (TA-1790) is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor with IC50 values of 5.2 nM, 630 nM, 5700 nM, 6200 nM, 12000 nM, 27000 nM, 51000 nM and 53000 nM for PDE-5, PDE-6, PDE-4, PDE-10, PDE-8, PDE-7, PDE-2 and PDE-1, respectively. Avanafil activates NO/cGMP/PKG signaling-pathway to decrease loss in BMD, bone atrophy, and oxidative stress. Avanafil inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Avanafil can be used for the research of erectile dysfunction and osteoporosis .

HY-N0757R

8-O-Acetylharpagide (Standard)	Structural Classification other families Iridoids Terpenoids Plants Source Classification	Reference Standards Akt Bcl-2 Family Apoptosis Adrenergic Receptor
8-O-Acetylharpagide (Standard) is the analytical standard of 8-O-Acetylharpagide. This product is intended for research and analytical applications. 8-O-Acetylharpagide is an iridoid glycoside compound. 8-O-Acetylharpagide exhibits anti-aging activity at low doses and anticancer activity at high doses. 8-O-Acetylharpagide induces late-stage apoptosis and necrosis-like death in cancer cells, and downregulates anti-apoptotic proteins such as Akt, p-Akt and Bcl-2. 8-O-Acetylharpagide is mainly metabolized in rats via demethylation, hydrolysis and glucuronidation, and its active metabolites downregulate the AKT/NF-κB/MMP9 signaling axis. 8-O-Acetylharpagide exerts vasoconstrictive effects by activating vascular α-adrenoceptor.

HY-N3169

Nyasicol (+)-Nyasicol	Curculigo orchioides Gaertn. Phenols Polyphenols Plants Amaryllidaceae Source Classification	Others
Nyasicol ((+)-Nyasicol) is an enzymatic (β-glucosidase) hydrolysis product of Compound 3 .

HY-N17882

Hydroxysaikosaponin A Bupleuroside III	Structural Classification Sonchus asper (L.) Hill Terpenoids Umbelliferae Plants Pentacyclic Triterpenoids Source Classification	Drug Derivative
Hydroxysaikosaponin A (Bupleuroside III) is the acid hydrolysis degradation product of Saikosaponin A (HY-N0246) .

HY-N18343

Ebelin lactone	Structural Classification Plants Actaea simplex (DC.) Wormsk. ex Fisch. & C. A. Mey. Rhamnaceae Steroids Source Classification	Drug Derivative
Ebelin lactone (Compound 1) is a sapogenin. Ebelin lactone is the acid hydrolysis product of Jujuboside A (HY-N0659) and Jujuboside B (HY-N0660) .

HY-126488R

H-Ser-His-OH (Standard)	Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite
H-Ser-His-OH (Standard) is the analytical standard of H-Ser-His-OH. This product is intended for research and analytical applications. H-Ser-His-OH is a short peptide with hydrolysis cleavage activity, an endogenous metabolite .

HY-N13110

23-Aldehyde-16-O-angeloybarringtogenol C	Triterpenes Terpenoids Camellia sinensis (L.) O. Ktze. Plants Source Classification Theaceae	Others
23-Aldehyde-16-O-angeloybarringtogenol C (compound 7) is a tea seed saponin, an acid hydrolysis product obtained by oxidative alkaline degradation. Tea seed saponins have potential quinine oxidoreductase inducing activity .

HY-180668

2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline is a product of the hydrolysis of 5-hydroxyisourate. 2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline undergoes stereoselective decarboxylation by the action of 2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase to give CO₂ and (S)-allantoin .

HY-N2423B

(E/Z)-Sinigrin free base (E/Z)-Allyl-glucosinolate free base; (E/Z)-2-Propenyl-glucosinolate free base	Structural Classification Glucosinolates Plants Brassicaceae Source Classification Mutarda nigra (L.) Bernh.	NF-κB p38 MAPK Apoptosis
(E/Z)-Sinigrin ((E/Z)-Allyl-glucosinolate; (E/Z)-2-Propenyl-glucosinolate) free base is an orally active aliphatic thioglucoside anti-leukemia compound. Allyl isothiocyanate, produced by the hydrolysis of (E/Z)-sinigrin free base by myrosinase, has an IC₅₀ of 2.71 μM against HL60 leukemia cells. The hydrolysis products of (E/Z)-sinigrin free base can further activate apoptosis pathways, inhibit NF-κB and MAPK signaling pathways, and induce phase II metabolic enzyme activity, thus exhibiting anti-cancer, anti-inflammatory, antibacterial, antioxidant, and wound healing activities. (E/Z)-Sinigrin free base can be used in research on cancer, inflammation-related diseases (such as atherosclerosis), and infectious diseases. (E/Z)-Sinigrin free base can be naturally extracted from the seeds of Brassica nigra, Brassica juncea, and other Brassicaceae plants such as broccoli and Brussels sprouts. Methyl pechueloate is a guaiane-type sesquiterpene ester compound and a potential precursor of xerantholide. It is useful in the structural elucidation and biosynthetic pathway studies of sesquiterpenoids. Methyl pechueloate can be naturally extracted from the aerial parts of Pechuel-Loeschea leibnitziae (Kuntze) O. Hoffm .

HY-113972R

Methyl mycophenolate (Standard)	Structural Classification Monophenols Microorganisms Marine natural products Phenols Marine microorganism	Reference Standards Others
Avanafil (Standard) is the analytical standard of Avanafil. This product is intended for research and analytical applications. Avanafil (TA-1790) is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor with IC50 values of 5.2 nM, 630 nM, 5700 nM, 6200 nM, 12000 nM, 27000 nM, 51000 nM and 53000 nM for PDE-5, PDE-6, PDE-4, PDE-10, PDE-8, PDE-7, PDE-2 and PDE-1, respectively. Avanafil activates NO/cGMP/PKG signaling-pathway to decrease loss in BMD, bone atrophy, and oxidative stress. Avanafil inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Avanafil can be used for the research of erectile dysfunction and osteoporosis .

Cat. No.	Product Name	Chemical Structure

HY-146925S

15:0 Lyso PC-d5

15:0 Lyso PC-d₅ is deuterium labeled 15:0 Lyso PC (HY-W329357). 15:0 Lyso PC is a lysophosphatidylcholine (Lyso PC), a product of phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine (PC) and is involved in cell membrane remodeling and inflammatory signaling. 15:0 Lyso PC demonstrates significant lipid metabolism disturbances in the serum of patients with ischemic heart disease (IHD) and ischemic cardiomyopathy (ICM). 15:0 Lyso PC can be used as a lipid biomarker for cardiovascular disease.

Cat. No.	Product Name		Classification

HY-150251

SD-91 STAT3 degrader-2		PROTAC Synthesis
SD-91 (STAT3 degrader-2), a product of the hydrolysis of SD-36 (HY-129602), is a selective PROTAC-based STAT3 degrader with a K_i of 5.5 nM. SD-91 displays >300-fold selectivity over other STAT family protein members. SD-91 potently induces degradation of STAT3 protein in cells. SD-91 has anticancer effects, such as myeloid leukemia, lymphoma (Pink: ligand for target protein (HY-150895); Black: linker; Blue: E3 ligase ligand; E3 ligase ligand+linker: HY-176506) .

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