2. Others Metabolic Enzyme/Protease
  3. Reference Standards Endogenous Metabolite Phosphodiesterase (PDE)
  4. Vardenafil hydrochloride trihydrate (Standard)

Vardenafil hydrochloride trihydrate (Standard) 

Art. -Nr.: HY-B0442BR
Handling Instructions Technical Support

Vardenafil (hydrochloride trihydrate) (Standard) is the analytical standard of Vardenafil (hydrochloride trihydrate). This product is intended for research and analytical applications. Vardenafil hydrochloride trihydrate is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil hydrochloride trihydrate shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4. Vardenafil hydrochloride trihydrate competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil hydrochloride trihydrate can be used for the research of erectile dysfunction, hepatitis, diabetes-.

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Vardenafil hydrochloride trihydrate (Standard)

Vardenafil hydrochloride trihydrate (Standard) Chemische Struktur

CAS. Nr. : 330808-88-3

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Information
Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molekulargewicht

579.11

Formel

C23H39ClN6O7S
CAS. Nr.
SMILES

O=C1N=C(C2=CC(S(=O)(N3CCN(CC)CC3)=O)=CC=C2OCC)NN4C1=C(C)N=C4CCC.Cl.O.O.O
Structure Classification
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Vardenafil hydrochloride trihydrate (Standard) Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vardenafil hydrochloride trihydrate (Standard)330808-88-3Reference StandardsEndogenous MetabolitePhosphodiesterase (PDE)cGMPselectivesmoothmuscleNOstimulationerectiledysfunctionVardenafilimpotencepharmacokineticserectile dysfunctionhepatitisZucker diabetic fatty (ZDF) ratsdiabetesInhibitorinhibitorinhibit

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