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Cat. No.: HY-76476

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(S)-Tetrahydrofuran-3-ol

Name: (S)-Tetrahydrofuran-3-ol
Brand: MedChemExpress
SKU: HY-76476
Price: 30.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: (+)-3-Hydroxytetrahydrofuran)

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Based on 1 Customer Validation

(S)-Tetrahydrofuran-3-ol ((+)-3-Hydroxytetrahydrofuran) is a secondary alcohol and the (S)-enantiomer of Tetrahydrofuran-3-ol. (S)-Tetrahydrofuran-3-ol serves as a crucial chiral alcohol intermediate for the human immunodeficiency virus inhibitor Amprenavir (HY-17430). (S)-Tetrahydrofuran-3-ol is applicable to researches on chiral biocatalysis and synthesis of HIV protease inhibitor intermediates.

For research use only. We do not sell to patients.

Purity: 99.94%
CAS No.: 86087-23-2
Formula: C₄H₈O₂
Molecular Weight:88.11

Storage:

Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

(S)-Tetrahydrofuran-3-ol Chemical Structure

CAS No.: 86087-23-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
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Biological Activity

Description

In Vitro

(S)-Tetrahydrofuran-3-ol ((+)-3-Hydroxytetrahydrofuran) functions as a reference standard for chiral GC identification of enzymatic reduction products, with a distinct retention time ~6 s shorter than its R-isomer under the specified analytical conditions^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 86087-23-2
Appearance Liquid (Density: 1.103 g/cm³)
Molecular Weight 88.11
Formula C₄H₈O₂
Color Colorless to light yellow
SMILES

O[C@@H]1COCC1
Synonyms

(+)-3-Hydroxytetrahydrofuran
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sim BR, et al. Origin of the Unexpected Enantioselectivity in the Enzymatic Reductions of 5-Membered-Ring Heterocyclic Ketones Catalyzed by Candida parapsilosis Carbonyl Reductases. Catalysts. 2022;12:1086.

[2]. Nobili A, et al. Use of 'small but smart' libraries to enhance the enantioselectivity of an esterase from Bacillus stearothermophilus towards tetrahydrofuran-3-yl acetate. The FEBS journal. 2013 Jul;280(13):3084-93.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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- In Vitro
Chemical Information
Purity & Documentation
References

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(S)-Tetrahydrofuran-3-ol