86087-23-2
Chemical Structure
(S)-Tetrahydrofuran-3-ol
Synonym(s): (+)-3-Hydroxytetrahydrofuran
- CAS No.: 86087-23-2
- Formula:C4H8O2
- Molecular Weight:88.11
IUPAC Name: (S)-tetrahydrofuran-3-ol
InChIKey: XDPCNPCKDGQBAN-BYPYZUCNSA-N
SMILES: O[C@@H]1COCC1
Biological Activity: (S)-Tetrahydrofuran-3-ol ((+)-3-Hydroxytetrahydrofuran) is a secondary alcohol and the (S)-enantiomer of Tetrahydrofuran-3-ol. (S)-Tetrahydrofuran-3-ol serves as a crucial chiral alcohol intermediate for the human immunodeficiency virus inhibitor Amprenavir (HY-17430). (S)-Tetrahydrofuran-3-ol is applicable to researches on chiral biocatalysis and synthesis of HIV protease inhibitor intermediates[1][2].
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(S)-Tetrahydrofuran-3-ol | 99.94% | (S)-Tetrahydrofuran-3-ol ((+)-3-Hydroxytetrahydrofuran) is a secondary alcohol and the (S)-enantiomer of Tetrahydrofuran-3-ol. (S)-Tetrahydrofuran-3-ol serves as a crucial chiral alcohol intermediate for the human immunodeficiency virus inhibitor Amprenavir (HY-17430). (S)-Tetrahydrofuran-3-ol is applicable to researches on chiral biocatalysis and synthesis of HIV protease inhibitor intermediates. | ||||||||||||||||||||
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(S)-Tetrahydrofuran-3-ol (Standard) | ≥98% | (S)-Tetrahydrofuran-3-ol (Standard) ((+)-3-Hydroxytetrahydrofuran (Standard)) is the analytical standard of (S)-Tetrahydrofuran-3-ol (HY-76476). This product is intended for research and analytical applications. (S)-Tetrahydrofuran-3-ol ((+)-3-Hydroxytetrahydrofuran) is a secondary alcohol and the (S)-enantiomer of Tetrahydrofuran-3-ol. (S)-Tetrahydrofuran-3-ol serves as a crucial chiral alcohol intermediate for the human immunodeficiency virus inhibitor Amprenavir (HY-17430). (S)-Tetrahydrofuran-3-ol is applicable to researches on chiral biocatalysis and synthesis of HIV protease inhibitor intermediates. | ||||||||||||||||||||
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- [1]. Sim BR, et al. Origin of the Unexpected Enantioselectivity in the Enzymatic Reductions of 5-Membered-Ring Heterocyclic Ketones Catalyzed by Candida parapsilosis Carbonyl Reductases. Catalysts. 2022;12:1086.
- [2]. Nobili A, et al. Use of 'small but smart' libraries to enhance the enantioselectivity of an esterase from Bacillus stearothermophilus towards tetrahydrofuran-3-yl acetate. The FEBS journal. 2013 Jul;280(13):3084-93.