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Results for "

glcnac

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (3) Akt (1) Amino Acid Derivatives (2) Aminotransferases (Transaminases) (1) Antibiotic (1) Apoptosis (1) Autophagy (1) Bacterial (7) Biochemical Assay Reagents (42) Caspase (1) Collagen (1) Drug Derivative (2) Drug Intermediate (3) Endogenous Metabolite (22) Epigenetic Reader Domain (1) Exosomes (1) FAK (1) Fluorescent Dye (11) Fungal (1) Galectin (1) Glycosidase (10) Glycosyltransferase (4) GSK-3 (1) HDAC (1) Influenza Virus (1) Insecticide (1) Interleukin Related (1) Isotope-Labeled Compounds (1) MDM-2/p53 (1) mTOR (1) NF-κB (1) OGA (4) OGT (13) P2Y Receptor (1) PARP (1) Potassium Channel (1) PROTACs (1) Reactive Oxygen Species (ROS) (1) Ser/Thr Protease (1) SULT (1) Target Protein Ligand-Linker Conjugates (1) Tau Protein (1) TGF-β Receptor (1) TNF Receptor (1) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (31) Endocrinology (3) Infection (13) Inflammation/Immunology (4) Metabolic Disease (24) Neurological Disease (4)
Click Chemistry:	Azide (5) Alkynes (1)
Oligonucleotides:	Nucleoside Analogs (1)

120

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-119738

OSMI-1 40+ Cited Publications	OGT Acyltransferase	Metabolic Disease
OSMI-1 is a cell-permeable *O-GlcNAc* transferase (OGT) inhibitor with an IC₅₀** value of 2.7 μM. OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans .

HY-12588

Thiamet G 45+ Cited Publications	OGA Autophagy	Cancer
Thiamet G is a potent and selective inhibitor of O-GlcNAcase (OGA), which acts to remove O-GlcNAc from modified proteins, with K_i of 20 nM for human OGA.

HY-114361

OSMI-4 25+ Cited Publications	OGT Acyltransferase	Metabolic Disease
OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor, with an EC₅₀ of 3 μM in cells.

HY-112174

*UDP-GlcNAc* disodium** 5+ Cited Publications UDP-α-D-N-Acetylglucosamine disodium	OGT	Metabolic Disease
UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (OGT).

HY-112942A

CMP-Sialic acid sodium salt 4 Publications Verification CMP-Neu5Ac sodium salt	Endogenous Metabolite	Metabolic Disease
CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of *UDP-GlcNAc* 2-epimerase**. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

HY-147063

N-Acetyl-α-D-glucosamine 1-phosphate disodium	Endogenous Metabolite	Others
N-acetyl-α-d-glucosamine 1-phosphate disodium (GlcNAc-1-P) is an ectopic sugar phosphate and a key intermediate in N-glycoprotein biosynthesis. N-acetyl-α-d-glucosamine 1-phosphate disodium serves as a metabolic precursor of teichoic acid and muramic acid, which are components of bacterial cell walls .

HY-175222

GlcNAc-MurNAc	Toll-like Receptor (TLR) NF-κB Caspase TNF Receptor Interleukin Related	Metabolic Disease Inflammation/Immunology
GlcNAc-MurNAc, a disaccharide, is a TLR4 agonist with a K_d of 383 μM for murine TLR4. GlcNAc-MurNAc directly binds to TLR4 and activates its downstream NF-κB and IRF pathways. GlcNAc-MurNAc improves Dextran sulfate sodium salt (DSS) (HY-116282C)-induced colitis in mice through a TLR4-dependent mechanism. GlcNAc-MurNAc can be used for the study of inflammatory bowel disease .

HY-145934A

UDP-GlcNAz disodium	OGT Biochemical Assay Reagents Glycosidase	Metabolic Disease
UDP-GlcNAz disodium is the analogue of UDP-GlcNAc disodium (HY-112174). UDP-GlcNAc disodium is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GlcNAc from the nucleotide sugar to a saccharide or peptide acceptor. UDP-GlcNAc disodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .

HY-N9446

*H-Asn(glcnac-beta-D)-OH*	Endogenous Metabolite	Others
H-Asn(glcnac-beta-D)-OH is an endogenous metabolite present in Urine that can be used for the research of NGLY1-CDDG .

HY-W039953

Ac4GlcNAz N-azidoacetylglucosamine-tetraacylated	Biochemical Assay Reagents	Others
Ac4GlcNAz (N-azidoacetylglucosamine-tetraacylated) is an azido-tagged analogue of N-acetylglucosamine (GlcNAC). It features azide functionality on the N-acyl side chain and is acetylated to aid in cell membrane permeation. Once in the cell, the acetylated compound is deprotected and takes part in the hexosamine biosynthetic pathway by action of GlcNAc kinase. The resulting modified proteins are detected by the addition of fluorescent tags under Cu(I)-catalyzed azide-alkyne cycloaddition conditions.

HY-112942

CMP-Sialic acid CMP-Neu5Ac	Endogenous Metabolite	Metabolic Disease
CMP-Sialic acid (CMP-Neu5Ac) is an allosteric inhibitor of *UDP-GlcNAc* 2-epimerase**. CMP-Sialic acid provides a substrate for Golgi sialyltransferases. CMP-Sialic acid is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

HY-E70032

N-Acetylhexosamine kinase (NahK)	Endogenous Metabolite	Metabolic Disease
N-Acetylhexosamine kinase (NahK) is an anomeric kinase acting on a glucose-type substrate. N-Acetylhexosamine kinase catalyzes the phosphorylation of GlcNAc or GalNAc at the anomeric C1 position with ATP to form N-acetylhexosamine 1-phosphate (GlcNAc-1P/GalNAc-1P) .

HY-N8515C

*UDP-3-O-acyl-GlcNAc* disodium** UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine disodium	Endogenous Metabolite	Infection Others
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) disodium is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-W585865

*UDP-3-O-acyl-GlcNAc* Tris** UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine Tris	Endogenous Metabolite	Infection
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) Tris is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-148113

PG 34	OGT	Others
PG 34 is a weak O-GlcNAc transferase (OGT) inhibitor (IC₅₀=68 μM), and a close structural analog of OSMI-1 (HY-119738) .

HY-164390

6′SLN Neu5Acα2-6Galβ1-4glcnac	Endogenous Metabolite	Infection Cancer
6′SLN is a cancer-related extracellular vesicle (EVs) surface glycan that serves as a key form of protein glycosylation in EVs. 6′SLN is also a sialic acid derivative that can interact with hemagglutinins (HAs) from human and avian influenza virus strains, making it useful for research into anti-influenza drugs .

HY-131940

3-O-Methyl-N-acetyl-D-glucosamine 3-O-Methyl-glcnac	Insecticide	Metabolic Disease
3-O-Methyl-N-acetyl-D-glucosamine is a potent inhibitor of N-acetylglucosamine kinase. 3-O-Methyl-N-acetyl-D-glucosamine potently inhibits glucose phosphorylation by N-acetylglucosamine kinase whereas glucokinase is not at all affected by this hexosamine .

HY-139793

UDP-glucosamine disodium	OGT Endogenous Metabolite	Metabolic Disease
UDP-glucosamine (UDP-GlcNAc) disodium is a substrate for O-GlcNAc transferase, which catalyzes the attachment of O-GlcNAc to proteins. O-GlcNAcase catalyzes the removal of O-GlcNAc from proteins. UDP-glucosamine (UDP-GlcNAc) disodium is the end product of the hexosamine biosynthesis pathway, which is regulated primarily by glucose-6-phosphate-Glutamine:fructose-6-phosphate amidotransferase (GFAT) .

HY-W039921

2-[(Azidoacety)amino]-2-deoxy-D-galactose N-Azidoacetylgalactosamine; GalNAz	Biochemical Assay Reagents	Others
2-[(Azidoacety)amino]-2-deoxy-D-galactose targets O-GlcNAc-modified proteins. By detecting and targeting O-GlcNAc-modified proteins, 2-[(Azidoacety)amino]-2-deoxy-D-galactose can serve as a chemical tag for intracellular sugar chain metabolism .

HY-E70138

β-1,4-Galactosyltransferase 7 EC:2.4.1.133; B4GALT7	Glycosyltransferase	Others
β-1,4-Galactosyltransferase 7 has exclusive specificity for the donor substrate UDP-galactose and all transfer galactose in a β-1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. .

HY-141488

Lacto-N-biose I Galβ1-3glcnac	Endogenous Metabolite	Endocrinology
Lacto-N-biose I (Galβ1-3GlcNAc), as an endogenous metabolite, is an acceptor for the α1,2-fucosyltransferase enzyme from Helicobacter pylori .

HY-148596

UDP-GlcNAc UDP-N-Acetyl-D-glucosamine; Uridine diphospho-N-acetylglucosamine; UDP-N-acetylglucosamine	Endogenous Metabolite P2Y Receptor Drug Intermediate	Infection
UDP-GlcNAc (UDP-N-Acetyl-D-glucosamine) is an important component and precursor of bacterial peptidoglycan. UDP-GlcNAc also acts as a full agonist of the P2Y₁₄ receptor and inhibits the formation of cAMP. UDP-GlcNAc can be used in studies related to bacterial infections .

HY-E70883

Endoglycosidase S (D233Q mutant) EndoS D233Q	Glycosidase	Others
Endoglycosidase S (D233Q mutant) (EndoS D233Q) is a mutant endoglycosidase, which catalyzes the glycosylation of Trastuzumab (HY-P9907)-GlcNAc with the functionalized, non-natural glycans to give glycosylated monoclonal Abs (mAbs) carrying two glycans each functionalized with two reaction handles .

HY-149552

Ac4-5SGlcNAc	OGT	Cancer
Ac4-5SGlcNAc is an *O-GlcNAc* transferase (OGT*) inhibitor. Ac4-5SGlcNAc converts intracellularly to UDP-5SGlcNAc, which competes with native UDP-GlcNAc* (HY-148596) to block OGT catalytic activity, reduces cellular UDP-GlcNAc pools, and limits global protein O-GlcNAcylation. Ac4-5SGlcNAc reduces OGA levels via feedback, alters lectin signal intensities and glycan-related band masses. Ac4-5SGlcNAc can be used for the research of breast cancer .

HY-E70070

Endo-β-N-acetylglucosaminidase (Endo A)	Bacterial	Others
Endo-β-N-acetylglucosaminidase (Endo A) is an Endo-β-N-acetylglucosaminidases (ENGases) from Arthrobacter protophormiae. Endo-β-N-acetylglucosaminidase (Endo A) can transfer a high-mannose type oligosaccharide to monosaccharides such as N-acetylglucosamine (GlcNAc) and glucose to form a new oligosaccharide. Endo-β-N-acetylglucosaminidase (Endo A) catalyzes glycopeptide synthesis by using Man3GlcNAc-oxazoline .

HY-E70136

Endo-β-Galactosidase Keratan-sulfate endo-1,4-beta-galactosidase; Keratanase	Others	Metabolic Disease
Endo-β-Galactosidase catalyzes the hydrolysis of internal β1-4 galactose linkages in unbranched, repeating poly-N-acetyllactosamine ([GlcNAc- (1-3)Gal- (1-4)]_n) structures .

HY-150177

Mannose 6 phosphate	Drug Intermediate	Metabolic Disease
Mannose 6 phosphate is an essential precursor for mannosyl glycoconjugates, including lipid-linked oligosaccharides (LLO; glucose3mannose9GlcNAc2-P-P-dolichol) used for protein N-glycosylation. Mannose 6 phosphate causes specific LLO cleavage. Mannose 6 phosphate causes specific degradation of G3M9Gn2-P-P-Dol. Complexes containing Mannose 6 phosphate can remodel the dermal collagen network, improve skin biomechanical properties, and reverse visible signs of aging. Mannose 6 phosphate can be used in research related to skin aging .

HY-137823

4-Nitrophenyl-N-acetyl-β-D-galactosaminide	Endogenous Metabolite	Cancer
4-Nitrophenyl-N-acetyl-β-D-galactosaminide has inhibitory activity against *GlcNAc* and GalNAc with K_is of 1.15 mM and 0.51 mM, respectively. 4-Nitrophenyl-N-acetyl-β-D-galactosaminide is extracted from Trichomonas foetus (T. foetus)

HY-W039939

2-Azido-2-deoxy-D-glucose, 98% 2-ADG, 98%	Biochemical Assay Reagents OGT	Cancer
2-Azido-2-deoxy-D-glucose, 98% (2-ADG, 98%) is a substrate of O-GlcNAc transferase (OGT). 2-Azido-2-deoxy-D-glucose, 98% can be transferred from UDP-GlcAz to proteins in vitro via OGT mediation. When delivered as AcGlcAz, 2-Azido-2-deoxy-D-glucose, 98% enables the labeling and investigation of O-GlcNAc-modified nuclear and cytoplasmic proteins in cells. 2-Azido-2-deoxy-D-glucose, 98% undergoes strain-promoted [3+2] azide-alkyne cycloaddition (SPAAC) with technetium- ^99m-labeled dibenzocyclooctyne derivatives in vivo. 2-Azido-2-deoxy-D-glucose, 98% can be used in sarcoma-related research .

HY-177892A

*UDP-2-alkyne-GlcNAc* disodium**	Drug Derivative Biochemical Assay Reagents	Others
UDP-2-alkyne-GlcNAc disodium (Compound 3) is a UDP-GlcNAc (HY-148596) derivative. UDP-2-alkyne-GlcNAc disodium can be used for the remodeling of cell surface glycans .

HY-112174S

*UDP-GlcNAc-13C disodium* UDP-α-D-N-Acetylglucosamine-13C disodium	Isotope-Labeled Compounds	Metabolic Disease
UDP-GlcNAc- ¹³C (disodium) is the ¹³C labeled UDP-GlcNAc Disodium Salt. UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (O .

HY-E70025

N-Acetylglucosamine-1-P uridyltransferase, Homo sapien glcnac1pUT	Others	Others
N-acetylglucosamine-1-P uridyltransferase (AGX1) (EC 2.3.1.157) (GlcNAc1pUT) is a bifunctional acetyltransferase/uridyltransferase. N-acetylglucosamine-1-P uridyltransferase (AGX1) binds GlcNAc-1-P and UTP, and catalyzes an uridyltransfer reaction to synthesize UDP-GlcNAc. N-acetylglucosamine-1-P uridyltransferase (AGX1) is a bifunctional enzyme exclusive to prokaryotes .

HY-W145586

GlcNAcβ(1-3)GalNAc-α-Thr glcnac beta(1-3)GalNAc-alpha-Thr	Biochemical Assay Reagents	Others
GlcNAcβ(1-3)GalNAc-α-Thr is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W145622

*Galβ(1-3)[Neu5Acα(2-6)]GlcNAc-β-pNP* Gal beta(1-3)[Neu5Ac alpha(2-6)]glcnac-beta-pNP	Biochemical Assay Reagents	Others
Galβ(1-3)[Neu5Acα(2-6)]GlcNAc-β-pNP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-141464

*Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH* Fmoc-Asn(Ac3AcNH-beta-Glc)-OH	Amino Acid Derivatives	Cancer
Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH (Fmoc-Asn(Ac3AcNH-beta-Glc)-OH) can be used in the synthesis of silicon-fluoride acceptor (SiFA) derivatized octreotate derivatives. SiFA-octreotate analogues, as tumor imaging agents, are useful tool for the research of positron emission tomography (PET) .

HY-145934B

UDP-GlcNAz	OGT Biochemical Assay Reagents Glycosidase	Metabolic Disease
UDP-GlcNAz is the analogue of UDP-GlcNAc disodium (HY-112174). UDP-GlcNAc disodium is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GlcNAc from the nucleotide sugar to a saccharide or peptide acceptor. UDP-GlcNAc disodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .

HY-125278

OGT-IN-4	OGT	Others
OGT-IN-4 (compound 4a) is an O-GlcNAc transferase (OGT) inhibitor with a K_d of 8 nM. OGT-IN-4 can be utilized in OGT related research .

HY-W145534

GlcNAcβ(1-3)GalNAc-α-pNP	Biochemical Assay Reagents	Others
GlcNAcβ(1-3)GalNAc-α-pNP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-NP163

Wheat germ agglutinin-AF350 WGA-AF350	Fluorescent Dye	Cancer
Wheat germ agglutinin-AF350 (WGA-AF350) is a plant lectin that contains the fluorescent dye AF350, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF350 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .

HY-143285

AMC-GlcNAc	Fluorescent Dye	Infection
AMC-GlcNAc (compound 1) is a potent fluorogenic probe for detection and characterization of β-hexosaminidase enzyme activity. AMC-GlcNAc enables continuous monitoring by turn-on fluorescence and fluorescence signal is constant over a wide pH range (Ex=325 nm, Em=390 nm). AMC-GlcNAc enables ratiometric fluorescence detection with high sensitivity and low background, which can be used to screen for recombinant dispersin B activity in E. coli cell lysate .

HY-W351294

*N-GlcNAc-Biotin*	Biochemical Assay Reagents	Others
N-GlcNAc-Biotin is a biotinylated biochemical assay reagent, that can be used as a biological material or organic compound for life science related research .

HY-178510

*JQ1-S(GlcNAc)Cq*	PROTACs Epigenetic Reader Domain	Cancer
JQ1-S(GlcNAc)Cq is a sugar-coated BRD4 PROTAC degrader. JQ1-S(GlcNAc)Cq can inhibit the formation of the ternary complex between CRBN and BRD4(BD1/BD2). JQ1-S(GlcNAc)Cq can be used for the research of cancer . (Structure Note: Pink: BRD4 ligand (HY-78695); Blue: CRBN ligand (HY-178514); Black: linker (HY-W105727); BRD4 ligand-Linker: (HY-178519))

HY-104004A

*Fmoc-Ser(O-β-D-GlcNAc(OAc)3)-OH* Fmoc-Ser-(glcnac(Ac)3-beta-D)-OH; Fmoc-Ser[glcnac(Ac)3-β-D]-OH; Fmoc-Ser(Ac3AcNH-β-Glc)-OH	Amino Acid Derivatives	Others
Fmoc-Ser(O-β-D-GlcNAc(OAc)3)-OH is a serine derivative .

HY-W706304

Gal1-β-4GlcNAc1-β-6Gal	Biochemical Assay Reagents	Others
Gal1-β-4GlcNAc1-β-6Gal is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-N8515

UDP-3-O-acyl-GlcNAc UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine	Endogenous Metabolite	Infection
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-E70286

N-Acetylglucosaminyltransferase V MGAT4B	Biochemical Assay Reagents	Cancer
N-Acetylglucosaminyltransferase V (MGAT4B) is the enzyme that catalyzes the formation of the β1,6-GlcNAc branch of N-glycans in the Golgi apparatus using UDP-GlcNAc as the donor substrate. N-Acetylglucosaminyltransferase V is involved in cancer malignancy and autoimmune disease etiology .

HY-E70880

Endoglycosidase CC (N180H mutant) EndoCC N180H	Glycosidase	Others
Endoglycosidase CC (N180H mutant) (EndoCC N180H) is a mutant endoglycosidase, which efficiently and specifically recognizes core fucose and O-GlcNAc .

HY-E70881

Endoglycosidase F3 (D165A mutant) EndoF3 D165A	Glycosidase	Others
Endoglycosidase F3 (D165A mutant) (EndoF3 D165A) is a mutant endoglycosidase, which efficiently and specifically recognizes core fucose and O-GlcNAc .

HY-P2858

β-Mannosidase	Glycosidase	Metabolic Disease
β-Mannosidase is a lysosomal exo‑acting enzyme. β-Mannosidase catalyzes hydrolysis of β‑1,4‑linked mannosides, non‑reducing terminal mannoses in N‑glycoproteins, and Man‑β‑1,4‑GlcNAc linkages to release mannose. β-Mannosidase contributes to glycoprotein catabolism and supports Bifidobacteria colonization via N‑glycan depolymerization. β-Mannosidase can be used for the research of β-mannosidosis and β-mannosidase deficiency .

HY-185060

N-Acetyllactosamine-C2-NH2	Drug Intermediate	Others
N-Acetyllactosamine-C2-NH2 (Compound β-D-Gal-(l-4)-β-D- GlcNAc-(l-4))-l-ethylamine) is a disaccharide compound and is the core backbone component for constructing sialylated glycans (sialosides) .

Cat. No.	Product Name	Type

HY-143285

AMC-GlcNAc

Fluorescent Dye

AMC-GlcNAc (compound 1) is a potent fluorogenic probe for detection and characterization of β-hexosaminidase enzyme activity. AMC-GlcNAc enables continuous monitoring by turn-on fluorescence and fluorescence signal is constant over a wide pH range (Ex=325 nm, Em=390 nm). AMC-GlcNAc enables ratiometric fluorescence detection with high sensitivity and low background, which can be used to screen for recombinant dispersin B activity in E. coli cell lysate .

Cat. No.	Product Name	Type

HY-145934A

UDP-GlcNAz disodium

Biochemical Assay Reagents

UDP-GlcNAz disodium is the analogue of UDP-GlcNAc disodium (HY-112174). UDP-GlcNAc disodium is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GlcNAc from the nucleotide sugar to a saccharide or peptide acceptor. UDP-GlcNAc disodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .

HY-NP163C

Wheat germ agglutinin-AF555 WGA-AF555	Biochemical Assay Reagents
Wheat germ agglutinin-AF555 (WGA-AF555) is a plant lectinthat contains the fluorescent dye AF555, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF555 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .

HY-NP163D

Wheat germ agglutinin-AF594 WGA-AF594	Biochemical Assay Reagents
Wheat germ agglutinin-AF594 (WGA-AF594) is a plant lectin that contains the fluorescent dye AF594, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF594 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .

HY-W039921

2-[(Azidoacety)amino]-2-deoxy-D-galactose N-Azidoacetylgalactosamine; GalNAz	Biochemical Assay Reagents
2-[(Azidoacety)amino]-2-deoxy-D-galactose targets O-GlcNAc-modified proteins. By detecting and targeting O-GlcNAc-modified proteins, 2-[(Azidoacety)amino]-2-deoxy-D-galactose can serve as a chemical tag for intracellular sugar chain metabolism .

HY-E70138

β-1,4-Galactosyltransferase 7 EC:2.4.1.133; B4GALT7	Biochemical Assay Reagents
β-1,4-Galactosyltransferase 7 has exclusive specificity for the donor substrate UDP-galactose and all transfer galactose in a β-1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. .

HY-NP163E

Wheat germ agglutinin-AF647 WGA-AF647	Biochemical Assay Reagents
Wheat germ agglutinin-AF647 (WGA-AF647) is a plant lectin that contains the fluorescent dye AF647, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF647 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .

HY-E70145

N-Acetylglucosaminyltransferase III EC:2.4.1.144; MGAT3	Biochemical Assay Reagents
N-Acetylglucosaminyltransferase III (EC:2.4.1.144 MGAT3) transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides and produces a bisecting GlcNAc .

HY-W039939

2-Azido-2-deoxy-D-glucose, 98%

2-ADG, 98%

Biochemical Assay Reagents

2-Azido-2-deoxy-D-glucose, 98% (2-ADG, 98%) is a substrate of O-GlcNAc transferase (OGT). 2-Azido-2-deoxy-D-glucose, 98% can be transferred from UDP-GlcAz to proteins in vitro via OGT mediation. When delivered as AcGlcAz, 2-Azido-2-deoxy-D-glucose, 98% enables the labeling and investigation of O-GlcNAc-modified nuclear and cytoplasmic proteins in cells. 2-Azido-2-deoxy-D-glucose, 98% undergoes strain-promoted [3+2] azide-alkyne cycloaddition (SPAAC) with technetium- ^99m-labeled dibenzocyclooctyne derivatives in vivo. 2-Azido-2-deoxy-D-glucose, 98% can be used in sarcoma-related research .

HY-W145586

GlcNAcβ(1-3)GalNAc-α-Thr glcnac beta(1-3)GalNAc-alpha-Thr	Biochemical Assay Reagents
GlcNAcβ(1-3)GalNAc-α-Thr is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W145622

*Galβ(1-3)[Neu5Acα(2-6)]GlcNAc-β-pNP* Gal beta(1-3)[Neu5Ac alpha(2-6)]glcnac-beta-pNP	Biochemical Assay Reagents
Galβ(1-3)[Neu5Acα(2-6)]GlcNAc-β-pNP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W145534

GlcNAcβ(1-3)GalNAc-α-pNP	Biochemical Assay Reagents
GlcNAcβ(1-3)GalNAc-α-pNP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-NP163

Wheat germ agglutinin-AF350 WGA-AF350	Biochemical Assay Reagents
Wheat germ agglutinin-AF350 (WGA-AF350) is a plant lectin that contains the fluorescent dye AF350, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF350 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .

HY-W351294

*N-GlcNAc-Biotin*	Biochemical Assay Reagents
N-GlcNAc-Biotin is a biotinylated biochemical assay reagent, that can be used as a biological material or organic compound for life science related research .

HY-W706304

Gal1-β-4GlcNAc1-β-6Gal

Biochemical Assay Reagents

Gal1-β-4GlcNAc1-β-6Gal is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-E70142

Glucosaminyl (N-acetyl) Transferase 1 EC:2.4.1.102; GCNT1	Biochemical Assay Reagents
Glucosaminyl (N-acetyl) Transferase 1 ( EC:2.4.1.102, GCNT1) is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch and play an important role in cancer .

HY-NP163I

Wheat germ agglutinin-AF680 WGA-AF 680	Biochemical Assay Reagents
Wheat germ agglutinin-AF680 (WGA-AF 680) is a plant lectin that contains the fluorescent dye AF680, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF680 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .

HY-NP163J

Wheat germ agglutinin-AF405 WGA-AF 405	Biochemical Assay Reagents
Wheat germ agglutinin-AF405 (WGA-AF 405) is a plant lectin that contains the fluorescent dye AF405, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF405 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .

HY-W016030

X-GlcNAc	Biochemical Assay Reagents
X-GlcNAc is a biochemical assay reagent.

HY-W145539

GlcNAcβ(1-3)[GlcNAcβ(1-6)]GalNAc-α-Thr glcnac beta(1-3)[glcnac beta(1-6)]GalNAc-alpha-Thr	Biochemical Assay Reagents
GlcNAcβ(1-3)[GlcNAcβ(1-6)]GalNAc-α-Thr is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W698379

Gal1-b-4GlcNAc-α-PNP	Biochemical Assay Reagents
Gal1-b-4GlcNAc-α-PNP is a biochemical assay reagent.

HY-W145631

*GalNAcβ(1-4)GlcNAc-β-pNP* GalNAc beta(1-4)glcnac-beta-pNP	Biochemical Assay Reagents
GalNAcβ(1-4)GlcNAc-β-pNP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W698411

GlcNAc1-β-6GalNAc-α-PNP

Biochemical Assay Reagents

GlcNAc1-β-6GalNAc-α-PNP is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W698354

Gal1-β-3GlcNAc1-β-Ome

Biochemical Assay Reagents

Gal1-β-3GlcNAc1-β-Ome is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W698353

Fuc1-α-3GlcNAc1-β-Ome

Biochemical Assay Reagents

Fuc1-α-3GlcNAc1-β-Ome is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-E70166

Carbohydrate Sulfotransferase 6 EC:2.8.2.21; CHST6; glcnac6ST-5	Biochemical Assay Reagents
Carbohydrate Sulfotransferase 6 (EC:2.8.2.21) can catalyze sulphate transfer to position 6 of non-reducing GlcNAc residues of keratan .

HY-E70167

Carbohydrate Sulfotransferase 7 EC:2.8.2.17; CHST7; glcnac6ST-4	Biochemical Assay Reagents
Carbohydrate Sulfotransferase 7 (EC:2.8.2.17) can catalyze sulphate transfer to position 6 of non- GlcNAc residues and to position 6 of the GalNAc residue of chondroitin .

HY-E70162

Carbohydrate Sulfotransferase 2 EC:2.8.2.-; CHST; glcnac6ST-1	Biochemical Assay Reagents
Carbohydrate Sulfotransferase 2 (EC:2.8.2.-) can catalyze sulphate transfer to position 6 of non-reducing GlcNAc residues within keratan-like structures on N-linked glycans and within mucin-associated glycans .

HY-E70164

Carbohydrate Sulfotransferase 4 EC:2.8.2.-; CHST4; glcnac6ST2	Biochemical Assay Reagents
Carbohydrate Sulfotransferase 4 (EC:2.8.2.-) can catalyze sulphate transfer to the hydroxyl group at C-6 position of the non-reducing GlcNAc residue within O-linked mucin-type glycans .

HY-W145556

Galβ(1-3)GlcNAcβ(1-3)Galβ(1-4)Glc-β-pNP Gal beta(1-3)glcnac beta(1-3)Gal beta(1-4)Glc-beta-pNP	Biochemical Assay Reagents
Galβ(1-3)GlcNAcβ(1-3)Galβ(1-4)Glc-β-pNP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-158454

FA2B glycan (G0B), 2-AB labelled FA2B N-linked oligosaccharide, 2-AB labelled; G0F with bisecting glcnac, 2-AB labelled	Biochemical Assay Reagents
FA2B glycan (G0B), 2-AB labelled (FA2B N-linked oligosaccharide, 2-AB labelled; G0F with bisecting GlcNAc, 2-AB labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-W416177

2,3,4,6-Tetra-O-benzoyl-α-D-galactopyranoside trichloroacetimidate	Biochemical Assay Reagents
X-GlcNAc is a biochemical assay reagent.

HY-158455

FA2[3]BG1 & FA2[6]BG1 glycan (G1B), 2-AA labelled FA2[3]BG1 & FA2[6]BG1 glycan N-linked oligosaccharide, 2-AA labelled; G1F with bisecting glcnac, 2-AA labelled	Biochemical Assay Reagents
FA2[3]BG1 & FA2[6]BG1 glycan (G1B), 2-AA labelled (FA2[3]BG1 & FA2[6]BG1 glycan N-linked oligosaccharide, 2-AA labelled; G1F with bisecting GlcNAc, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-E70165

Carbohydrate Sulfotransferase 5 EC:2.8.2.-; CHST5; GST4-α	Biochemical Assay Reagents
Carbohydrate Sulfotransferase 5 (EC:2.8.2.-) can catalyze sulphate transfer to position 6 of non- GlcNAc residues and O-linked sugars of mucin-type acceptors .

HY-E70140

α-1,4-N-Acetylglucosaminyltransferase 4 EC 2.4.1; A4GNT	Biochemical Assay Reagents
α-1,4-N-Acetylglucosaminyltransferase 4 (EC 2.4.1, A4GNT) catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans and suppresses H. pylori growth .

HY-NP163H

Wheat germ agglutinin-AF750 WGA-AF750	Biochemical Assay Reagents
Wheat germ agglutinin-AF750 (WGA-AF750) is a plant lectin that contains the fluorescent dye AF750, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF750 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .

HY-W779188

GlcNAc1-β-3GalNAc	Biochemical Assay Reagents
GlcNAc1-β-3GalNAc is a biochemical assay reagent.

HY-W145553

*GalNAcβ(1-3)GlcNAc-β-pNP*	Biochemical Assay Reagents
GalNAcβ(1-3)GlcNAc-β-pNP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W355093

2-(Acetylamino)-2-deoxy-4-O-(6-deoxy-α-L-galactopyranosyl)-D-glucose

Fuc-α-2-4-glcnac

Biochemical Assay Reagents

2-(Acetylamino)-2-deoxy-4-O-(6-deoxy-α-L-galactopyranosyl)-D-glucose (Fuc-α-2-4-GlcNAc) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W699180

Fuc1-α-2Gal1-β-3GlcNAc-β-PNP

Biochemical Assay Reagents

Fuc1-α-2Gal1-β-3GlcNAc-β-PNP is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W357155

Gal1-β-3GlcNAc-β-PNP

Galactosyl-N-acetylglucosaminyl-β-p-nitrophenyl

Biochemical Assay Reagents

Gal1-β-3GlcNAc-β-PNP (Galactosyl-N-acetylglucosaminyl-β-p-nitrophenyl) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W699164

Gal1-β-4GlcNAc-β-Bn

Benzyl β-D-galactopyranosyl-(1→4)-β-D-N-acetylglucosamine

Biochemical Assay Reagents

Gal1-β-4GlcNAc-β-Bn (Benzyl β-D-galactopyranosyl-(1→4)-β-D-N-acetylglucosamine) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-158453

FA2B glycan (G0B), 2-AA labelled FA2B N-linked oligosaccharide, 2-AA labelled; G0F with bisecting glcnac, 2-AA labelled	Biochemical Assay Reagents
FA2B glycan (G0B), 2-AA labelled (FA2B N-linked oligosaccharide, 2-AA labelled; G0F with bisecting GlcNAc, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158456

FA2[3]BG1 & FA2[6]BG1 glycan (G1B), 2-AB labelled FA2[3]BG1 & FA2[6]BG1 glycan N-linked oligosaccharide, 2-AB labelled; G1F with bisecting glcnac, 2-AB labelled	Biochemical Assay Reagents
FA2[3]BG1 & FA2[6]BG1 glycan (G1B), 2-AB labelled (FA2[3]BG1 & FA2[6]BG1 glycan N-linked oligosaccharide, 2-AB labelled; G1F with bisecting GlcNAc, 2-AB labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-NP163B

Wheat germ agglutinin-AF532 WGA-AF532	Biochemical Assay Reagents
Wheat germ agglutinin-AF532 (WGA-AF532) is a plant lectin that contains the fluorescent dye AF532, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF532 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .

HY-NP163K

Wheat germ agglutinin-AF430 WGA-AF 430	Biochemical Assay Reagents
Wheat germ agglutinin-AF430 (WGA-AF 430) is a plant lectin that contains the fluorescent dye AF430, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF430 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .

Cat. No.	Product Name	Target	Research Area

HY-P5375

*O-Linked GlcNAc* transferase substrate**	Peptides	Others
O-Linked GlcNAc transferase substrate is a biological active peptide. (A peptide substrate of O-linked GlcNAc transferase (OGT), a eukaryotic glycosyltransferase that uses UDP-GlcNAc as a glycosyl donor.)

HY-P4752

*KWKHGAEIVYKSPVV-{S(GlcNAc-β-D)}-GDTSPRHLSNVK-{K(biotinyl)}-NH2*	Peptides	Others
KWKHGAEIVYKSPVV-{S(GlcNAc-β-D)}-GDTSPRHLSNVK-{K(biotinyl)}-NH2 is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-104004A

*Fmoc-Ser(O-β-D-GlcNAc(OAc)3)-OH* Fmoc-Ser-(glcnac(Ac)3-beta-D)-OH; Fmoc-Ser[glcnac(Ac)3-β-D]-OH; Fmoc-Ser(Ac3AcNH-β-Glc)-OH	Amino Acid Derivatives	Others
Fmoc-Ser(O-β-D-GlcNAc(OAc)3)-OH is a serine derivative .

HY-P5747

Glycocin F	Peptides	Others
Glycocin F is a antimicrobial peptide with activity against L. plantarum .

HY-P10572

HG1 Toxin	Ser/Thr Protease Potassium Channel	Inflammation/Immunology Endocrinology
HG1 Toxin is a peptide found in the venom of the scorpion Heterometrus fulvipes, which has the activity of inhibiting potassium channel Kv1.3. HG1 Toxin also has the activity of inhibiting trypsin (K_i=107 nM) and can be used in the study of autoimmune diseases .

HY-P11330

L-Ala-D-Glu-m-DAP-D-Ala-D-Ala	Bacterial	Infection
L-Ala-D-Glu-m-DAP-D-Ala-D-Ala is a key structured peptide of peptidoglycan of gram-negative bacteria. Peptidoglycan is a network of L-Ala-D-Glu-m-DAP-D-Ala-D-Ala cross-linking the repeated units of N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (MurNAc). L-Ala-D-Glu-m-DAP-D-Ala-D-Ala can be used for bacterial metabolic labeling research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-A0098

Tunicamycin 150+ Cited Publications	Structural Classification Antifungal Classification of Application Fields Antibacterial Disease Research Other Antibiotics Infection Microorganisms Antibiotics Antiviral Anticancer Inflammation/Immunology Disease Research Fields Source Classification	Antibiotic Influenza Virus Fungal Bacterial Aminotransferases (Transaminases) Exosomes
Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity .Tunicamycin increases exosome release in cervical cancer cells .

HY-112942A

CMP-Sialic acid sodium salt 4 Publications Verification CMP-Neu5Ac sodium salt	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of *UDP-GlcNAc* 2-epimerase**. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

HY-147063

N-Acetyl-α-D-glucosamine 1-phosphate disodium	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
N-acetyl-α-d-glucosamine 1-phosphate disodium (GlcNAc-1-P) is an ectopic sugar phosphate and a key intermediate in N-glycoprotein biosynthesis. N-acetyl-α-d-glucosamine 1-phosphate disodium serves as a metabolic precursor of teichoic acid and muramic acid, which are components of bacterial cell walls .

HY-N9446

*H-Asn(glcnac-beta-D)-OH*	Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
H-Asn(glcnac-beta-D)-OH is an endogenous metabolite present in Urine that can be used for the research of NGLY1-CDDG .

HY-112942

CMP-Sialic acid CMP-Neu5Ac	Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
CMP-Sialic acid (CMP-Neu5Ac) is an allosteric inhibitor of *UDP-GlcNAc* 2-epimerase**. CMP-Sialic acid provides a substrate for Golgi sialyltransferases. CMP-Sialic acid is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

HY-N3677

Dammarenediol II	Triterpenes Structural Classification other families Boswellia freerana Terpenoids Plants Source Classification	OGT Akt mTOR GSK-3 Reactive Oxygen Species (ROS) Apoptosis PARP MDM-2/p53
Dammarenediol II is a ginsenoside precursor . Dammarenediol II reduces the activity of O-GlcNAc transferase (OGT) and downregulates the global O-GlcNAcylation level. Dammarenediol II inhibits the phosphorylation of Akt, mTOR and GSK3β. Dammarenediol II inhibits human carboxylesterase activity, VEGF-induced ROS production, stress fiber formation and vascular endothelial cadherin disruption. Dammarenediol II promotes cell apoptosis (apoptosis), increases the levels of cleaved PARP1 and p53, and inhibits retinal microvascular leakage. Dammarenediol II can be used in studies related to liver cancer and diabetic retinopathy .

HY-N8515C

*UDP-3-O-acyl-GlcNAc* disodium** UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine disodium	Infection Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) disodium is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-W585865

*UDP-3-O-acyl-GlcNAc* Tris** UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine Tris	Infection Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) Tris is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-139793

UDP-glucosamine disodium	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	OGT Endogenous Metabolite
UDP-glucosamine (UDP-GlcNAc) disodium is a substrate for O-GlcNAc transferase, which catalyzes the attachment of O-GlcNAc to proteins. O-GlcNAcase catalyzes the removal of O-GlcNAc from proteins. UDP-glucosamine (UDP-GlcNAc) disodium is the end product of the hexosamine biosynthesis pathway, which is regulated primarily by glucose-6-phosphate-Glutamine:fructose-6-phosphate amidotransferase (GFAT) .

HY-141488

Lacto-N-biose I Galβ1-3glcnac	Polysaccharides Microorganisms Classification of Application Fields Disease Research Fields Saccharides Endocrinology Source Classification	Endogenous Metabolite
Lacto-N-biose I (Galβ1-3GlcNAc), as an endogenous metabolite, is an acceptor for the α1,2-fucosyltransferase enzyme from Helicobacter pylori .

HY-148596

UDP-GlcNAc UDP-N-Acetyl-D-glucosamine; Uridine diphospho-N-acetylglucosamine; UDP-N-acetylglucosamine	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Endogenous Metabolite P2Y Receptor Drug Intermediate
UDP-GlcNAc (UDP-N-Acetyl-D-glucosamine) is an important component and precursor of bacterial peptidoglycan. UDP-GlcNAc also acts as a full agonist of the P2Y₁₄ receptor and inhibits the formation of cAMP. UDP-GlcNAc can be used in studies related to bacterial infections .

HY-150177

Mannose 6 phosphate	Human Gut Microbiota Metabolites Endogenous metabolite Source Classification	Drug Intermediate
Mannose 6 phosphate is an essential precursor for mannosyl glycoconjugates, including lipid-linked oligosaccharides (LLO; glucose3mannose9GlcNAc2-P-P-dolichol) used for protein N-glycosylation. Mannose 6 phosphate causes specific LLO cleavage. Mannose 6 phosphate causes specific degradation of G3M9Gn2-P-P-Dol. Complexes containing Mannose 6 phosphate can remodel the dermal collagen network, improve skin biomechanical properties, and reverse visible signs of aging. Mannose 6 phosphate can be used in research related to skin aging .

HY-137823

4-Nitrophenyl-N-acetyl-β-D-galactosaminide	Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite
4-Nitrophenyl-N-acetyl-β-D-galactosaminide has inhibitory activity against *GlcNAc* and GalNAc with K_is of 1.15 mM and 0.51 mM, respectively. 4-Nitrophenyl-N-acetyl-β-D-galactosaminide is extracted from Trichomonas foetus (T. foetus)

HY-N8515

UDP-3-O-acyl-GlcNAc UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine	Natural Products Microorganisms Source Classification	Endogenous Metabolite
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-N8515B

*UDP-3-O-acyl-GlcNAc* diammonium** UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine diammonium	Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
UDP-3-O-acyl-GlcNAc diammonium is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

Species:	Human (7) Mouse (1) E.coli (1)
Tag:	SUMO (2) His (8) Myc (1) Fc (1)
Source:	HEK293 (4) E. coli (5)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P705511

	OGT Protein, Human (His, Myc) O-glcnac transferase subunit p110; O-linked N-acetylglucosamine transferase 110 kDa subunit	Human	E. coli

HY-P76823

	CHST5 Protein, Mouse (HEK293, Fc) Carbohydrate sulfotransferase 5; GST4; I-glcnac6ST; Gn6st-3	Mouse	HEK293
	CHST5 protein, utilizing PAPS, catalyzes sulfate transfer to position 6 of non-reducing GlcNAc residues in keratan, particularly in the cornea. This sulfonation is crucial for mediating keratan sulfate sulfation, a key process in maintaining corneal transparency. CHST5 acts on short and long carbohydrate substrates, emphasizing its role in corneal function and contribution to maintaining corneal transparency through keratan sulfate sulfation. CHST5 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CHST5 protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P703650

	OGT Protein, Human (His) 1 Publications Verification UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; O-glcnac transferase subunit p110; O-linked N-acetylglucosamine transferase 110 kDa subunit (OGT); OGT	Human	E. coli
	OGT Protein, Human (His) is the recombinant human-derived OGT protein, expressed by E. coli, with N-6*His & N-SUMO tag.

HY-P71488

	LpxC Protein, E.coli (His) lpxC; asmB; envA; b0096; JW0094; UDP-3-O-acyl-N-acetylglucosamine deacetylase; UDP-3-O-acyl-glcnac deacetylase; EC 3.5.1.108; Protein EnvA; UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase	E.coli	E. coli
	LpxC protein serves as a key enzyme in lipid A biosynthesis by catalyzing the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine, marking a key and crucial step in this important pathway. Through this enzymatic process, LpxC promotes the conversion of its substrate into UDP-3-O-myristoylglucosamine and acetate, making a significant contribution to lipid A biosynthesis. LpxC Protein, E.coli (His) is the recombinant E. coli-derived LpxC protein, expressed by E. coli , with N-His labeled tag.

HY-P71221

	POMGNT1 Protein, Human (HEK293, His) Protein O-Linked-Mannose Beta-1; 2-N-Acetylglucosaminyltransferase 1; POMGnT1; UDP-glcnac:Alpha-D-Mannoside Beta-1; 2-N-Acetylglucosaminyltransferase I.2; POMGNT1; MGAT1.2	Human	HEK293
	The POMGNT1 protein crucially directs O-mannosyl glycosylation, which adds N-acetylglucosamine to O-linked mannose residues on glycoproteins. It catalyzes GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr on α-dystroglycan and other O-mannosylated proteins, laying the foundation for subsequent carbohydrate addition. POMGNT1 Protein, Human (HEK293, His) is the recombinant human-derived POMGNT1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70957

	MAN1B1 Protein, Human (HEK293, His) Endoplasmic Reticulum Mannosyl-Oligosaccharide 1; 2-Alpha-Mannosidase; ER Alpha-1; 2-Mannosidase; ER Mannosidase 1; ERMan1; Man9glcnac2-Specific-Processing Alpha-Mannosidase; Mannosidase Alpha Class 1B Member 1; MAN1B1	Human	HEK293
	MAN1B1, integral to glycoprotein quality control, trims a single alpha-1,2-linked mannose from Man(9)GlcNAc(2), producing Man(8)GlcNAc(2). In the ERQC, elevated enzyme concentrations allow further trimming to Man(5-6)GlcNAc(2). This enzymatic function is crucial for glycoprotein processing and quality control in the endoplasmic reticulum, ensuring proper folding and maturation. MAN1B1 Protein, Human (HEK293, His) is the recombinant human-derived MAN1B1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70410

	MGAT2 Protein, Human (HEK293, His) rHuAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase/MGAT2, His ; Alpha-1; 6-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase; Beta-1; 2-N-acetylglucosaminyltransferase II; glcnac-T II; NT-II; Mannoside Acetylglucosaminyltransferase 2; N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase II; MGAT2	Human	HEK293
	The MGAT2 protein plays an important role in protein N-glycosylation, catalyzing the transfer of GlcNAc to the free terminal mannose in nascent N-linked glycan chains. This forms a second branch of the complex glycan and is critical for glycoprotein maturation and functional diversity. MGAT2 Protein, Human (HEK293, His) is the recombinant human-derived MGAT2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P705434

	B3GNT5 Protein, Human (His) Lactotriaosylceramide synthase; Lc3; Lc3 synthase; UDP-glcnac:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5; BGnT-5; Beta-1,3-Gn-T5; Beta-1,3-N-acetylglucosaminyltransferase 5; Beta3Gn-T5	Human	E. coli

HY-P71529

	ST3GAL3 Protein, Human (His-SUMO) 3 sialyltransferase; 3(4) glcnac alpha-2; 3-sialyltransferase 3; 3-sialyltransferase; 3-ST 3; 4-galactoside alpha-2; 4glcnac alpha 2 3 sialyltransferase; Alpha 2 3 sialyltransferase II; Alpha 2 3 sialyltransferase III; Alpha 2 3 ST 3; Alpha 2; Beta galactoside alpha 3 sialyltransferase 3; Beta-galactoside alpha-2; CMP N acetylneuraminate beta 1 4 galactoside alpha 2 3 sialyltransferase; CMP-N-acetylneuraminate-beta-1; EC 2.4.99.6; Gal beta 1 3; Gal beta 1 3(4) glcnac alpha 2 3 sialyltransferase; Gal beta 1 3(4)glcnac alpha 2 3 sialyltransferase; Gal beta-1; N acetyllactosaminide alpha 2 3 sialyltransferase; N-acetyllactosaminide alpha-2; OTTHUMP00000008820; OTTHUMP00000008821; OTTHUMP00000008822; OTTHUMP00000008823; Sialyltransferase 6 (N acetyllacosaminide alpha 2 3 sialyltransferase); Sialyltransferase 6; SIAT6; SIAT6_HUMAN; ST3 beta galactoside alpha 2 3 sialyltransferase 3; ST3 beta galactoside alpha 2,3 sialyltransferase 3; ST3Gal III; St3gal3; ST3GALII; ST3GalIII; ST3N	Human	E. coli
	ST3GAL3 protein plays a central role in cellular processes by catalyzing the formation of NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-α-2,3-Gal-beta-1,3-GalNAc- sequences are present in the terminal carbohydrate groups of glycoproteins and glycolipids. ST3GAL3 Protein, Human (His-SUMO) is the recombinant human-derived ST3GAL3 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

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HY-112174S

*UDP-GlcNAc-13C disodium*
UDP-GlcNAc- ¹³C (disodium) is the ¹³C labeled UDP-GlcNAc Disodium Salt. UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (O .

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HY-P89717

	GlcNAc kinase Antibody (YA9061)	WB, ICC/IF, IF-Tissue, IP, ELISA	human
	GlcNAc kinase Antibody (YA9061) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GlcNAc kinase.

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Cat. No.	Product Name		Classification

HY-145934A

UDP-GlcNAz disodium		Azide
UDP-GlcNAz disodium is the analogue of UDP-GlcNAc disodium (HY-112174). UDP-GlcNAc disodium is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GlcNAc from the nucleotide sugar to a saccharide or peptide acceptor. UDP-GlcNAc disodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .

HY-W039953

Ac4GlcNAz N-azidoacetylglucosamine-tetraacylated		Azide
Ac4GlcNAz (N-azidoacetylglucosamine-tetraacylated) is an azido-tagged analogue of N-acetylglucosamine (GlcNAC). It features azide functionality on the N-acyl side chain and is acetylated to aid in cell membrane permeation. Once in the cell, the acetylated compound is deprotected and takes part in the hexosamine biosynthetic pathway by action of GlcNAc kinase. The resulting modified proteins are detected by the addition of fluorescent tags under Cu(I)-catalyzed azide-alkyne cycloaddition conditions.

HY-W423080

TAMRA alkyne,5-isomer		Alkynes
TAMRA alkyne, 5-isomer (Compound 3) is an alkyne derivative of TAMRA and can be used for the enrichment, in-gel fluorescence detection, and identification of O-GlcNAc-modified proteins. TAMRA alkyne, 5-isomer contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Azide groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .

HY-W039921

2-[(Azidoacety)amino]-2-deoxy-D-galactose N-Azidoacetylgalactosamine; GalNAz		Azide
2-[(Azidoacety)amino]-2-deoxy-D-galactose targets O-GlcNAc-modified proteins. By detecting and targeting O-GlcNAc-modified proteins, 2-[(Azidoacety)amino]-2-deoxy-D-galactose can serve as a chemical tag for intracellular sugar chain metabolism .

HY-156232

Gal-GIcNAc-oxazoline		Azide
Gal-GIcNAc-oxazoline (compound 24) is an N-acetylglucosamine (GlcNAc) and azide-modified disaccharide that can be used to label antibodies. Gal-GIcNAc-oxazoline can be synthesized as an ADC via click chemistry .

HY-156230

Man-GIcNAc-oxazoline		Azide
Man-GIcNAc-oxazoline (compound 6) is an N-acetylglucosamine (GlcNAc) and azide-modified disaccharide that can be used to label antibodies. Man-GIcNAc-oxazoline can be synthesized as an ADC via click chemistry .

Cat. No.	Product Name		Classification

HY-177892A

*UDP-2-alkyne-GlcNAc* disodium**		Nucleoside Analogs
UDP-2-alkyne-GlcNAc disodium (Compound 3) is a UDP-GlcNAc (HY-148596) derivative. UDP-2-alkyne-GlcNAc disodium can be used for the remodeling of cell surface glycans .

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