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OSMI-4 

Cat. No.: HY-114361
Handling Instructions

OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor, with an EC50 of 3 μM in cells.

For research use only. We do not sell to patients.

OSMI-4 Chemical Structure

OSMI-4 Chemical Structure

CAS No. : 2260791-14-6

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor, with an EC50 of 3 μM in cells.

IC50 & Target

EC50: 3 μM (OGT)[1].

In Vitro

OSMI-4 (4b) is the best OGT inhibitor reported to date, with a ∼3 μM EC50 in cells, making it especially attractive for probing OGT’s complex biology[1].

References
Molecular Weight

604.09

Formula

C₂₇H₂₆ClN₃O₇S₂

CAS No.

2260791-14-6

SMILES

O=C1C=CC2=C(C=C(Cl)C(S(N[[email protected]@H](C(N(CC(OCC)=O)CC3=CC=CS3)=O)C4=C(OC)C=CC=C4)(=O)=O)=C2)N1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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OSMI-4
Cat. No.:
HY-114361
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OSMI-4

Cat. No.: HY-114361