1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 6′SLN

6′SLN  (Synonyms: Neu5Acα2-6Galβ1-4GlcNAc)

Cat. No.: HY-164390 Purity: 99.87%
Handling Instructions Technical Support

6′SLN is a cancer-related extracellular vesicle (EVs) surface glycan that serves as a key form of protein glycosylation in EVs. 6′SLN is also a sialic acid derivative that can interact with hemagglutinins (HAs) from human and avian influenza virus strains, making it useful for research into anti-influenza drugs.

For research use only. We do not sell to patients.

6′SLN

6′SLN Chemical Structure

CAS No. : 64364-50-7

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Description

6′SLN is a cancer-related extracellular vesicle (EVs) surface glycan that serves as a key form of protein glycosylation in EVs. 6′SLN is also a sialic acid derivative that can interact with hemagglutinins (HAs) from human and avian influenza virus strains, making it useful for research into anti-influenza drugs[1][2].

Molecular Weight

674.60

Formula

C25H42N2O19

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H](O[C@H]([C@@H]([C@H]1O)NC(C)=O)O)[C@H]1O[C@@H]([C@@H]([C@H]([C@H]2O)O)O)O[C@@H]2CO[C@]3(O[C@@]([C@@H]([C@H](C3)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (185.29 mM; Need ultrasonic)

DMSO : 50 mg/mL (74.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4824 mL 7.4118 mL 14.8236 mL
5 mM 0.2965 mL 1.4824 mL 2.9647 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 1.4824 mL 7.4118 mL 14.8236 mL 37.0590 mL
5 mM 0.2965 mL 1.4824 mL 2.9647 mL 7.4118 mL
10 mM 0.1482 mL 0.7412 mL 1.4824 mL 3.7059 mL
15 mM 0.0988 mL 0.4941 mL 0.9882 mL 2.4706 mL
20 mM 0.0741 mL 0.3706 mL 0.7412 mL 1.8529 mL
25 mM 0.0593 mL 0.2965 mL 0.5929 mL 1.4824 mL
30 mM 0.0494 mL 0.2471 mL 0.4941 mL 1.2353 mL
40 mM 0.0371 mL 0.1853 mL 0.3706 mL 0.9265 mL
50 mM 0.0296 mL 0.1482 mL 0.2965 mL 0.7412 mL
60 mM 0.0247 mL 0.1235 mL 0.2471 mL 0.6176 mL
H2O 80 mM 0.0185 mL 0.0926 mL 0.1853 mL 0.4632 mL
100 mM 0.0148 mL 0.0741 mL 0.1482 mL 0.3706 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
6′SLN
Cat. No.:
HY-164390
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