Search Result

Results for "

Photodynamic+therapy

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (21) Autophagy (4) Bacterial (5) Bcl-2 Family (2) Biochemical Assay Reagents (5) Carbonic Anhydrase (1) Caspase (1) Cholinesterase (ChE) (1) Dihydrofolate reductase (DHFR) (1) Drug Derivative (2) Drug Intermediate (1) Endogenous Metabolite (2) Epigenetic Reader Domain (1) Ferroptosis (5) Fluorescent Dye (9) Fungal (3) GLUT (1) HIF/HIF Prolyl-Hydroxylase (1) HIV (2) Isotope-Labeled Compounds (1) Ligands for E3 Ligase (1) Ligands for Target Protein for PROTAC (1) Liposome (1) Mitochondrial Metabolism (1) MMP (2) MOFs (1) PANoptosis (1) Parasite (4) Photosensitizer (21) PKC (3) Reactive Oxygen Species (ROS) (25) Reference Standards (8) STING (1) VEGFR (2) VSV (2) YAP (3)
By Research Areas:	Cancer (58) Endocrinology (1) Infection (8) Inflammation/Immunology (4) Metabolic Disease (2)
Oligonucleotides:	Liposome (1) Phospholipids (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0146

Verteporfin Maximum Cited Publications 266 Publications Verification CL 318952	YAP Apoptosis Autophagy Photosensitizer	Cancer
Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis . Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation .

HY-D0988

R-Phycoerythrin R-PE	Fluorescent Dye Apoptosis	Cancer
R-Phycoerythrin is found in Heterosiphonia japonica. R-Phycoerythrin is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex: 495 nm).

HY-128973

Pyropheophorbide-a 3 Publications Verification	Reactive Oxygen Species (ROS)	Cancer
Pyropheophorbide-a (Ppa) is a photosensitizer used in photodynamic therapy (PDT) for tumors. Pyropheophorbide-a exhibits phototoxic effects on tumor cells, such as cervical cancer cells, and also has anti-lipogenesis activity. Pyropheophorbide-a shows potential for research in the fields of cancer and age-related macular degeneration (AMD). Pyropheophorbide-a derivatives also demonstrate inhibitory activity against tumor cells .

HY-113011

Maltotriose 1 Publications Verification	Endogenous Metabolite	Others
Maltotriose is a maltooligosaccharide and a specific inducer of the Escherichia coli maltose operon. The oligosaccharide structure of Maltotriose acts as a highly efficient drug delivery carrier, which significantly enhances the targeting ability and water solubility of photosensitizers in photodynamic therapy for pancreatic cancer .

HY-16488

Temoporfin 10+ Cited Publications m-THPC; KW2345	Reactive Oxygen Species (ROS)	Cancer
Temoporfin (m-THPC), a reduced porphyrin, is a potent second-generation photosensitizer. Temoporfin can be used in the research of photodynamic therapy (PDT) for head and neck cancers .

HY-19204

Zinc phthalocyanine ZnPc	Ligands for Target Protein for PROTAC Reactive Oxygen Species (ROS) Apoptosis Caspase	Cancer
Zinc phthalocyanine (ZnPc) is commonly applied in industry (catalysts, photoconductors) and biomedical (photodynamic therapy, PDT). Zinc phthalocyanine can be used to photooxidise cyclohexane and is promising for research of solar-cell applications .

HY-P2213

GPLGIAGQ	MMP Apoptosis	Cancer
GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT) .

HY-128972

Purpurin 18 2 Publications Verification	Reactive Oxygen Species (ROS) Apoptosis	Others
Purpurin 18, a derivative of chlorophyll and a type of dihydroporphyrin, is used to produce photosensitizers. Purpurin 18 photodynamic therapy can induce cell apoptosis and has anti-tumor activity .

HY-N2575

Hypocrellin A 2 Publications Verification	PKC Bacterial Parasite HIV VSV VEGFR Bcl-2 Family Apoptosis	Infection Metabolic Disease Cancer
Hypocrellin A is a PKC inhibitor that exerts antidiabetic activity by reversing the effects of high glucose on endothelin (ET-1) expression. Hypocrellin A is also a photosensitizer for photodynamic therapy (PDT) with anticancer, antibacterial and antiviral activities, especially against human immunodeficiency virus (HIV). In addition, Hypocrellin-A also possesses anti-Leishmania activity (IC₅₀=0.27 μg/ml) .

HY-13722

HPPH 3 Publications Verification Photochlor	Reactive Oxygen Species (ROS)	Cancer
HPPH (Photochlor) is a second generation photosensitizer, which acts as a photodynamic therapy (PDT) agent.

HY-16477

Talaporfin sodium 4 Publications Verification ME2906; Mono-L-aspartyl chlorin e6; NPe6	Photosensitizer	Cancer
Talaporfin (ME2906) sodium is a chlorin based photosensitizer. Talaporfin sodium can be used for the research of various cancers by using photodynamic therapy (PDT) .

HY-16045

Hexaminolevulinate hydrochloride Hexyl 5-aminolevulinate hydrochloride; P-1206; 5-Aminolevulinic acid hexyl ester hydrochloride	Fluorescent Dye	Cancer
Hexaminolevulinate (Hexyl 5-aminolevulinate) hydrochloride, a porphyrin precursor, is a photosensitiser that can be used in photodynamic therapy (PDT) for certain tumor. Hexaminolevulinate hydrochloride can improve the visualisation of bladder tumours .

HY-137473

Methyl pyropheophorbide-a 2 Publications Verification Pyropheophorbide-a methyl ester	Apoptosis	Cancer
Methyl pyropheophorbide-a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide-a has photodynamic activity and can induce apoptosis and inhibit tumor growth .

HY-N1453

Hypocrellin B 1 Publications Verification	Apoptosis Fungal Parasite	Infection Cancer
Hypocrellin B, a pigment isolated from the fungi Hypocrella bambusae and Shiraia bambusicola, is an apoptosis inducer. Hypocrellin B can be used as a photosensitizer for photodynamic therapy of cancer. Hypocrellin B also has antimicrobial and antileishmanial activities .

HY-A0169A

Methyl aminolevulinate hydrochloride 1 Publications Verification	Reactive Oxygen Species (ROS) Photosensitizer	Cancer
Methyl aminolevulinate hydrochloride is a sensitizer used in photodynamic therapy (PDT). Methyl aminolevulinate hydrochloride penetrates the skin and induces the production of photoactive porphyrins including protoporphyrin IX in cells; upon exposure to appropriate light, it generates ROS, which triggers cellular oxidation and cell death. Methyl aminolevulinate hydrochloride acts as a photo-damage reversing agent through epidermal reconstruction, cytokine-mediated activation of dermal fibroblasts, elastin breakdown, new collagen formation, and compression of dilated capillaries. Methyl aminolevulinate hydrochloride reduces the expression of the proliferation marker K_i-67 and the early skin carcinogenesis marker TP53. Methyl aminolevulinate hydrochloride delays the onset of ultraviolet-induced skin tumors and reduces tumor burden in hairless mice. Methyl aminolevulinate hydrochloride is applicable to research related to actinic keratosis and basal cell carcinoma .

HY-N6743

Cercosporin CGP049090	PKC	Cancer
Cercosporin is produced by a plant pathogen, Pseudocercosporella capsellae. Cercosporin is a potent photosensitizer with a short activation wavelength, mostly suitable for superficial photodynamic therapy (PDT) treatments, especially when it is necessary to avoid perforations . Cercosporin contains the perylenequinone structural features necessary to PKC activity with an IC₅₀ of 0.6-1.3 μM .

HY-D1299

meso-CF3-BODIPY 2 CF3-substituted Tetramethyl BODIPY	Fluorescent Dye	Cancer
meso-CF3-BODIPY 2 (CF3-substituted Tetramethyl BODIPY) is a fluorescent dye with the absorption wavelength (λ_abs) of 553 nm and emission wavelength (λ_em) of 622 nm. meso-CF3-BODIPY 2 can be used in labeling reagents and photodynamic therapy .

HY-W130236

Methylene Violet 3RAX	Cholinesterase (ChE)	Cancer
Methylene Violet 3RAX is a phenazine dye to stain the mitochondria of cells. Methylene Violet 3RAX can change the molecular structure of DNA, undermine the module of DNA, and induce the generation of the reactive singlet oxygen. Methylene Violet 3RAX shows inhibition for human erythrocyte AChE and human plasma BChE with an K_is of 1.58, 0.51 μM, respectively. Methylene Violet 3RAX has the potential for the research of potential photosensitizers for mitochondrial targeting action in PDT (photodynamic therapy) .

HY-137475

Chlorin e6 trimethyl ester 1 Publications Verification	Reactive Oxygen Species (ROS)	Cancer
Chlorin e6 trimethyl ester, a methyl pheophorbide-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT) .

HY-W010417

4-Thiouracil	Reactive Oxygen Species (ROS)	Others
4-Thiouracil is a thionucleobase with cytostatic properties. 4-Thiouracil can be used as biological photoprobes to detect RNA structures and nucleic acid-nucleic acid contacts. 4-Thiouracil can also act as a strong ultraviolet A (UVA) photosensitizer, providing a source of the reactive oxygen species of O2. 4-Thiouracil is promising for research of photocross linking, photodamage, as well as photodynamic therapy .

HY-W854659

Chlorin e6 trisodium 15+ Cited Publications Ce6 trisodium	Photosensitizer	Cancer
Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll, belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm. Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation, enabling real-time identification of tumor boundaries and progression. Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions .

HY-151486

GLUT1-IN-1	GLUT	Cancer
GLUT1-IN-1 is a glucose transporter 1 (GLUT1) inhibitor and has a GLUT1-specific inactivation ability. GLUT1-IN-1 exhibits concentration-dependent cytotoxicity for HeLa, A549 and HepG2 cells with IC₅₀ values of 5.49 μM, 11.14 μM, and 8.73 μM, respectively. GLUT1-IN-1 can be used for the research of photodynamic therapy (PDT) and severals cancer .

HY-W127820

H2TMpyP-2 chloride Tetrakis(2-N-methylpyridyl)porphine chloride	Biochemical Assay Reagents Fluorescent Dye	Others
H2TMpyP-2 (tetrakis(2-N-methylpyridyl)porphine) chloride is an active photosensitizer with strong absorption properties in the visible to near-infrared region and excellent singlet oxygen quantum yield. Captisol-TMPyP complexes can be used in supramolecular nanosynthesis to increase singlet oxygen production, improve photostability and better photosensitization, and support photodynamic therapy activity. The Captisol:TMPyP complex also exhibited antibacterial activity against Escherichia coli and was cytotoxic against lung cancer A549 cells .

HY-111959

2-Selenouracil 1 Publications Verification	Reactive Oxygen Species (ROS)	Endocrinology
2-Selenouracil is a useful specialized photosensitizer for photodynamical therapy .

HY-137474

Purpurin 18 methyl ester	Photosensitizer	Cancer
Purpurin 18 methyl ester, a chlorophyll-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT). Purpurin 18 methyl ester has photodynamic activity to induce cancer cell death .

HY-B0146R

Verteporfin (Standard) CL 318952 (Standard)	Reference Standards YAP Apoptosis Autophagy	Cancer
Verteporfin (Standard) is the analytical standard of Verteporfin. This product is intended for research and analytical applications. Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis . Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation .

HY-116525

Octaethylporphyrin	Reactive Oxygen Species (ROS)	Cancer
Octaethylporphyrin is a porphyrin derivative. Octaethylporphyrin is a photodynamic therapy (PDT) agent .

HY-W035135

NPN12830	Photosensitizer	Others
NPN12830 is a dye compound. NPN12830 can be used in various photodynamic therapy research .

HY-W035145

Tris2,2′-bipyridineruthenium(II) hexafluorophosphate	Drug Intermediate	Others
Tris(2,2′-bipyridine)ruthenium(II)hexafluorophosphate can be used to prepare Ru(II)-containing photodynamic therapy (PDT) photosensitizers .

HY-13663

Lemuteporfin QLT-0074; DRM-05; EA 6	Photosensitizer Drug Derivative	Cancer
Lemuteporfin (QLT-0074) is a benzoporphyrin derivative, diethylene glycol functionalized chlorin-type photosensitizer. Lemuteporfin rapidly sensitizes cells to photodynamic therapy. Lemuteporfin has anticancer activity against acute lymphoblastic leukemia .

HY-16488R

Temoporfin (Standard) m-THPC (Standard); KW2345 (Standard)	Reactive Oxygen Species (ROS) Reference Standards	Cancer
Temoporfin (Standard) is the analytical standard of Temoporfin. This product is intended for research and analytical applications. Temoporfin (m-THPC), a reduced porphyrin, is a potent second-generation photosensitizer. Temoporfin can be used in the research of photodynamic therapy (PDT) for head and neck cancers .

HY-158710

1-Palmitoyl-2-pyropheophorbide a-sn-glycero-3-pc	Reactive Oxygen Species (ROS)	Cancer
1-Palmitoyl-2-pyropheophorbide a-sn-glycero-3-pc is a phospholipid-porphyrin conjugate. 1-Palmitoyl-2-pyropheophorbide a-sn-glycero-3-pc can be utilized in photodynamic therapy research .

HY-137473R

Methyl pyropheophorbide-a (Standard) Pyropheophorbide-a methyl ester (Standard)	Apoptosis Reference Standards	Cancer
Methyl pyropheophorbide-a (Standard) is the analytical standard of Methyl pyropheophorbide-a. This product is intended for research and analytical applications. Methyl pyropheophorbide-a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide-a has photodynamic activity and can induce apoptosis and inhibit tumor growth .

HY-P2213A

GPLGIAGQ TFA	MMP Apoptosis	Cancer
GPLGIAGQ TFA, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ TFA can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT) .

HY-179415

DHFR-IN-24	Dihydrofolate reductase (DHFR) Bacterial	Infection
DHFR-IN-24, a benzothiazole derivative, is a dihydrofolate reductase (DHFR) inhibitor. DHFR-IN-24 has intrinsic antibacterial activity against both Gram-positive and Gram-negative strains. DHFR-IN-24 synergistically combines DHFR inhibition with photodynamic therapy (PDT) for enhanced antibacterial activity against multidrug-resistant pathogens .

HY-N10611

Elsinochrome A	Reactive Oxygen Species (ROS) Apoptosis Autophagy Fungal Fluorescent Dye	Infection Cancer
Elsinochrome A is a perylene quinone photosensitizer, and can generate reactive oxygen species (ROS) to induce apoptosis and autophagy under light excitation. Elsinochrome A also shows antifungal activity against C. albicans biofilm through photodynamic antimicrobial chemotherapy (PACT). Elsinochrome A can be used for research of photodynamic therapy (PDT) (Ex: 460 nm) .

HY-113011R

Maltotriose (Standard)	Reference Standards Endogenous Metabolite	Others
Maltotriose (Standard) is the analytical standard of Maltotriose (HY-13011). This product is intended for research and analytical applications. Maltotriose is a maltooligosaccharide and a specific inducer of the Escherichia coli maltose operon. The oligosaccharide structure of Maltotriose acts as a highly efficient drug delivery carrier, which significantly enhances the targeting ability and water solubility of photosensitizers in photodynamic therapy for pancreatic cancer.

HY-W127809

Chlorin e4	Biochemical Assay Reagents	Others
Chlorin e4 is an organic compound belonging to the family of chlorins, which are macrocyclic compounds with a similar structure to porphyrins. It is commonly used to improve photodynamic therapy for cancer and other diseases. Chlorin e4 has multiple applications in medical research, including as a photosensitizer for localized tumor destruction. In addition, its antimicrobial properties and potential use in disinfection applications were investigated.

HY-W738979

Silicon naphthalocyanine dichloride	Photosensitizer
Silicon naphthalocyanine dichloride is a photosensitizer with potential anti-tumor activity. Silicon naphthalocyanine dichloride is used as a cancer-inhibiting compound in photodynamic therapy. Silicon naphthalocyanine dichloride can effectively absorb light energy of a specific wavelength, thereby generating oxygen free radicals that help destroy cancer cells. The biocompatibility of Silicon naphthalocyanine dichloride makes it show good prospects in medical applications.

HY-173417

Antibacterial agent 275	Bacterial	Infection Inflammation/Immunology
Antibacterial agent 275 (Ⅲ1) is a antibacterial agent, with a λ_max of 730 nm. Antibacterial agent 275 (Ⅲ1) can be used in the research for antimicrobial photodynamic therapy (aPDT) .

HY-16477A

Talaporfin ME2906 free acid; Mono-L-aspartyl chlorin e6 free acid; NPe6 free acid	Photosensitizer	Cancer
Talaporfin sodium, can be used in intraoperative photodynamic therapy (PDT) with a 664-nm semiconductor laser, was evaluated for efficacy and safety in treating primary malignant parenchymal brain tumors .

HY-175214

Antitumor photosensitizer-9	Reactive Oxygen Species (ROS) Photosensitizer	Cancer
Antitumor photosensitizer-9 is a near-infrared Photosensitizer (PS) with a high singlet oxygen production rate (relative rate = 1.79). Antitumor photosensitizer-9 exhibits strong phototoxicity against various cancer cells and induces ROS generation under light irradiation. Antitumor photosensitizer-9 inhibits tumor growth in vivo and exhibits excellent anticancer photodynamic therapy (PDT) efficacy at low drug and light doses. Antitumor photosensitizer-9 can be used in photodynamic therapy research .

HY-157943

Hexyl 5-aminolevulinate HAL	Fluorescent Dye	Cancer
Hexyl 5-aminolevulinate (HAL) is a photosensitizer, and can increase the efficiency of PDT due to the high lipophilicity. Hexyl 5-aminolevulinate can be used for research of photodynamic therapy (PDT) .

HY-168261

CQ-ER	Ferroptosis	Cancer
CQ-ER is a Coumarin (HY-N0709)-Quinazolinone based endoplasmic reticulum (ER)-targeted photosensitizer. CQ-ER can cause ferroptosis, thereby enhancing photodynamic therapy (PDT) .

HY-168097

Ferroptosis inducer-6	Ferroptosis Reactive Oxygen Species (ROS)	Cancer
Ferroptosis inducer 6 (6d) is a ferroptosis inducer with high potency for type I/-II photodynamic therapy by inducing ROS generation, oxidative stress and mitochondrial damage. Ferroptosis inducer 6 has anti-tumor activity .

HY-157051

[Ru(DIP)2TAP]Cl2	Photosensitizer	Cancer
[Ru(DIP)2TAP]Cl2, Ruthenium(II) polypyridyl compound, is a photosensitizer. [Ru(DIP)2TAP]Cl2 can be used for the research of photodynamic therapy (PDT) .

HY-151940

Mal-Pc	Reactive Oxygen Species (ROS)	Cancer
Mal-Pc is a versatile molecular photosensitizer designed based phthalocyanine and maleimides. Mal-Pc can react with GSH to deplete GSH and reduce aggregation, thereby improving ROS (Reactive Oxygen Species)-mediated effect of photodynamic therapy (PDT) in cancer cells .

HY-168854

TBC-1	Photosensitizer Reactive Oxygen Species (ROS)	Cancer
TBC-1 is a chlorophyll-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT). TBC-1 efficiently generats Type-I ROS and endoplasmic reticulum targeting ability. TBC-1 shows biocompatibility and PDT efficiency in vitro under both normoxia and hypoxia .

HY-W127725

Thymolphthalexon tetrasodium	Biochemical Assay Reagents	Others
Thymolphthalexon (tetrasodium) is an organic compound commonly used as a reagent in biochemical assays. It belongs to the family of thioxanthone derivatives and has strong antioxidant properties. Thymolphthalexon has several applications in the study of free radical response, oxidative stress, and aging. In addition, it can be used as a photosensitizer in photodynamic therapy for the improvement of cancer and other diseases.

HY-162824

Antitumor photosensitizer-6	Apoptosis	Cancer
Antitumor photosensitizer-6 (Compound Ru2) shows synergetic type I/II photosensitization and photocatalytic activity upon 595 nm light excitation. Ru2 induces intracellular redox imbalance and affects the biosynthetic and metabolic processes, leading to cell apoptosis. Antitumor photosensitizer-6 can be used for research of photodynamic therapy (PDT) .

Cat. No.	Product Name	Type

HY-D0988

R-Phycoerythrin R-PE	Fluorescent Dye
R-Phycoerythrin is found in Heterosiphonia japonica. R-Phycoerythrin is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex: 495 nm).

HY-19204

Zinc phthalocyanine ZnPc	Fluorescent Dye
Zinc phthalocyanine (ZnPc) is commonly applied in industry (catalysts, photoconductors) and biomedical (photodynamic therapy, PDT). Zinc phthalocyanine can be used to photooxidise cyclohexane and is promising for research of solar-cell applications .

HY-D1299

meso-CF3-BODIPY 2 CF3-substituted Tetramethyl BODIPY	Fluorescent Dye
meso-CF3-BODIPY 2 (CF3-substituted Tetramethyl BODIPY) is a fluorescent dye with the absorption wavelength (λ_abs) of 553 nm and emission wavelength (λ_em) of 622 nm. meso-CF3-BODIPY 2 can be used in labeling reagents and photodynamic therapy .

HY-W127725

Thymolphthalexon tetrasodium

Fluorescent Dye

Thymolphthalexon (tetrasodium) is an organic compound commonly used as a reagent in biochemical assays. It belongs to the family of thioxanthone derivatives and has strong antioxidant properties. Thymolphthalexon has several applications in the study of free radical response, oxidative stress, and aging. In addition, it can be used as a photosensitizer in photodynamic therapy for the improvement of cancer and other diseases.

HY-D2620

CAR-2	Fluorescent Dye
CAR-2 is a BODIPY-based photosensitizer that induces ferroptosis in photodynamic therapy (PDT) by targeting the endoplasmic reticulum (ER) and lipid droplets (LDs). CAR-2 exhibits phototoxicity in breast cancer cells with IC₅₀ of 0.01-0.02 μM. CAR-2 exhibits antitumor efficacy in 4T1 xenograft mouse models .

HY-D0988A

R-Phycoerythrin (concentrated solution)

R-PE (concentrated solution)

Fluorescent Dye

R-Phycoerythrin (R-PE) (concentrated solution) is found in Heterosiphonia japonica. R-Phycoerythrin (concentrated solution) is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin (concentrated solution) can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin (concentrated solution) can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex/Em = 496/578 nm) .

HY-D0988B

R-Phycoerythrin ammonium sulfate precipitate

R-PE ammonium sulfate precipitate

Fluorescent Dye

R-Phycoerythrin (R-PE) (ammonium sulfate precipitate) is found in Heterosiphonia japonica. R-Phycoerythrin (ammonium sulfate precipitate) is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin (concentrated solution) can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin (ammonium sulfate precipitate) can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex/Em = 496/578 nm) .

Cat. No.	Product Name	Type

HY-W854659

Chlorin e6 trisodium

15+ Cited Publications

Ce6 trisodium

Biochemical Assay Reagents

Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll, belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm. Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation, enabling real-time identification of tumor boundaries and progression. Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions .

HY-W127809

Chlorin e4

Biochemical Assay Reagents

Chlorin e4 is an organic compound belonging to the family of chlorins, which are macrocyclic compounds with a similar structure to porphyrins. It is commonly used to improve photodynamic therapy for cancer and other diseases. Chlorin e4 has multiple applications in medical research, including as a photosensitizer for localized tumor destruction. In addition, its antimicrobial properties and potential use in disinfection applications were investigated.

Cat. No.	Product Name	Target	Research Area

HY-P2213

GPLGIAGQ	MMP Apoptosis	Cancer
GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT) .

HY-P2213A

GPLGIAGQ TFA	MMP Apoptosis	Cancer
GPLGIAGQ TFA, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ TFA can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113011

Maltotriose 1 Publications Verification	Structural Classification Human Gut Microbiota Metabolites Polysaccharides Microorganisms Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Saccharides Source Classification	Endogenous Metabolite
Maltotriose is a maltooligosaccharide and a specific inducer of the Escherichia coli maltose operon. The oligosaccharide structure of Maltotriose acts as a highly efficient drug delivery carrier, which significantly enhances the targeting ability and water solubility of photosensitizers in photodynamic therapy for pancreatic cancer .

HY-N2575

Hypocrellin A 2 Publications Verification	Infection Quinones Structural Classification Microorganisms other families Classification of Application Fields Phenols Polyphenols Plants Disease Research Fields Source Classification	PKC Bacterial Parasite HIV VSV VEGFR Bcl-2 Family Apoptosis
Hypocrellin A is a PKC inhibitor that exerts antidiabetic activity by reversing the effects of high glucose on endothelin (ET-1) expression. Hypocrellin A is also a photosensitizer for photodynamic therapy (PDT) with anticancer, antibacterial and antiviral activities, especially against human immunodeficiency virus (HIV). In addition, Hypocrellin-A also possesses anti-Leishmania activity (IC₅₀=0.27 μg/ml) .

HY-N1453

Hypocrellin B 1 Publications Verification	Infection Microorganisms other families Classification of Application Fields Phenols Polyphenols Pigments Plants Disease Research Fields Source Classification Food Research	Apoptosis Fungal Parasite
Hypocrellin B, a pigment isolated from the fungi Hypocrella bambusae and Shiraia bambusicola, is an apoptosis inducer. Hypocrellin B can be used as a photosensitizer for photodynamic therapy of cancer. Hypocrellin B also has antimicrobial and antileishmanial activities .

HY-N6743

Cercosporin CGP049090	Quinones Structural Classification Microorganisms Classification of Application Fields Phenols Polyphenols Disease Research Fields Source Classification Cancer	PKC
Cercosporin is produced by a plant pathogen, Pseudocercosporella capsellae. Cercosporin is a potent photosensitizer with a short activation wavelength, mostly suitable for superficial photodynamic therapy (PDT) treatments, especially when it is necessary to avoid perforations . Cercosporin contains the perylenequinone structural features necessary to PKC activity with an IC₅₀ of 0.6-1.3 μM .

HY-137474

Purpurin 18 methyl ester	Natural Products other families Animals Classification of Application Fields Plants Disease Research Fields Source Classification Cancer	Photosensitizer
Purpurin 18 methyl ester, a chlorophyll-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT). Purpurin 18 methyl ester has photodynamic activity to induce cancer cell death .

HY-N10611

Elsinochrome A	Quinones Structural Classification Microorganisms Source Classification	Reactive Oxygen Species (ROS) Apoptosis Autophagy Fungal Fluorescent Dye
Elsinochrome A is a perylene quinone photosensitizer, and can generate reactive oxygen species (ROS) to induce apoptosis and autophagy under light excitation. Elsinochrome A also shows antifungal activity against C. albicans biofilm through photodynamic antimicrobial chemotherapy (PACT). Elsinochrome A can be used for research of photodynamic therapy (PDT) (Ex: 460 nm) .

HY-113011R

Maltotriose (Standard)	Structural Classification Human Gut Microbiota Metabolites Polysaccharides Microorganisms Endogenous metabolite Saccharides Source Classification	Reference Standards Endogenous Metabolite
Maltotriose (Standard) is the analytical standard of Maltotriose (HY-13011). This product is intended for research and analytical applications. Maltotriose is a maltooligosaccharide and a specific inducer of the Escherichia coli maltose operon. The oligosaccharide structure of Maltotriose acts as a highly efficient drug delivery carrier, which significantly enhances the targeting ability and water solubility of photosensitizers in photodynamic therapy for pancreatic cancer.

HY-N1453R

Hypocrellin B (Standard)	Microorganisms other families Phenols Polyphenols Plants Source Classification	Reference Standards Apoptosis Fungal Parasite
Hypocrellin B (Standard) is the analytical standard of Hypocrellin B. This product is intended for research and analytical applications. Hypocrellin B, a pigment isolated from the fungi Hypocrella bambusae and Shiraia bambusicola, is an apoptosis inducer. Hypocrellin B can be used as a photosensitizer for photodynamic therapy of cancer. Hypocrellin B also has antimicrobial and antileishmanial activities[1][2][3].

HY-N2575R

Hypocrellin A (Standard)	Structural Classification Natural Products Microorganisms other families Phenols Polyphenols Plants Source Classification	Reference Standards PKC Bacterial Parasite HIV VSV VEGFR Bcl-2 Family Apoptosis
Hypocrellin A (Standard) is the analytical standard of Hypocrellin A. This product is intended for research and analytical applications. Hypocrellin A is a PKC inhibitor that exerts antidiabetic activity by reversing the effects of high glucose on endothelin (ET-1) expression. Hypocrellin A is also a photosensitizer for photodynamic therapy (PDT) with anticancer, antibacterial and antiviral activities, especially against human immunodeficiency virus (HIV). In addition, Hypocrellin-A also possesses anti-Leishmania activity (IC50=0.27 μg/ml)[1][2][3][4][5][6][7][8][9].

Cat. No.	Product Name	Chemical Structure

HY-W769206

Talaporfin-13C4,15N
Talaporfin- ¹³C₄, ¹⁵N (ME2906 (free acid)- ¹³C₄, ¹⁵N) is the ¹³C- and ¹⁵N-labeled Talaporfin (HY-16477A). Talaporfin sodium, can be used in intraoperative photodynamic therapy (PDT) with a 664-nm semiconductor laser, was evaluated for efficacy and safety in treating primary malignant parenchymal brain tumors .

Cat. No.	Product Name		Classification

HY-158710

1-Palmitoyl-2-pyropheophorbide a-sn-glycero-3-pc		Phospholipids
1-Palmitoyl-2-pyropheophorbide a-sn-glycero-3-pc is a phospholipid-porphyrin conjugate. 1-Palmitoyl-2-pyropheophorbide a-sn-glycero-3-pc can be utilized in photodynamic therapy research .

HY-185390

Verteporfin liposome Liposomal verteporfin		Liposome
Verteporfin liposome is a liposome-encapsulated form of Verteporfin (HY-B0146). Verteporfin is a photosensitizer used in photodynamic therapy to eliminate abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin liposome prolongs drug circulation time and provides slow release, allowing the drug to accumulate in newly formed blood vessels.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Photodynamic+therapy

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Oligonucleotides

Natural
Products