TPAPyN
TPAPyN is a nitroreductase(NTR)-responsive type I photosensitizer. TPAPyN facilitates the imaging of hypoxic cancer cells and image-guided photodynamic therapy (PDT). TPAPyN does not emit fluorescence in the aqueous environment, but restores when NTR cleaves the nitrofuran quencher with aggregation-induced emission. TPAPyN can be used as a fluorescent probe for specific imaging of hypoxic cancer.
For research use only. We do not sell to patients.
- Formula: C32H28BrN3O5
- Molecular Weight:614.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Biological Activity
Description
Chemical Information
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Molecular Weight 614.49
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Formula C32H28BrN3O5
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SMILES
COC1=CC=C(N(C2=CC=C(OC)C=C2)C3=CC=C(/C=C/C4=CC=[N+](CC5=CC=C([N+]([O-])=O)O5)C=C4)C=C3)C=C1.[Br-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Hot Topics
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Topics Photodynamic Therapy: Past, Current, Future
Photodynamic therapy (PDT) is a light-activated therapeutic modality that combines photosensitizers, oxygen, and specific light wavelengths to generate reactive oxygen species for selective cellular destruction.
2026-06-02
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TPAPyN Related Classifications
HY-175163 Related Classifications
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