Zinc phthalocyanine
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Zinc phthalocyanine (ZnPc) is commonly applied in industry (catalysts, photoconductors) and biomedical (photodynamic therapy, PDT). Zinc phthalocyanine can be used to photooxidise cyclohexane and is promising for research of solar-cell applications.
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- Pureté : 98.0%
- CAS No.: 14320-04-8
- Formule: C32H16N8Zn
- Masse moléculaire:577.90
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Stockage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Activité biologique
Description
In Vitro
Zinc phthalocyanine (1-10 μM, 24 h) inhibits the growth of cancer cell Kyse-140 and OE-33 with IC50 of 1.41 μM and 3.35 μM[3].
Zinc phthalocyanine (1-10 μM, 24 h) is a photosensitizer that can be taken up by cancer cells and produces ROS under light irradiation of a specific wavelength (694 nm), impaires mitochondrial membrane integrity, activates caspase-3, and induces apoptosis[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Chick chorioallantoic membrane models[3]
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Dosage:10 µM
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Administration:topical application, single dose
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Result:Reduced tumor volume, destoryed the microvascular network.
Excitation (Ex)
620
Chemical Information
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CAS No. 14320-04-8
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Appearance Solid
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Masse moléculaire 577.90
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Formule C32H16N8Zn
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Color Purplish red to black
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SMILES
[N-]12[Zn+2]34[N-]5C6=NC(C7=CC=CC=C87)=[N]3C8=NC1=C(C=CC=C9)C9=C2N=C%10[N]4=C(C%11=CC=CC=C%10%11)N=C5C%12=CC=CC=C6%12
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Synonyms
ZnPc
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvant et solubilité
In Vitro:
DMF : < 1 mg/mL (insoluble)
* Zinc phthalocyanine is usually formulated as a suspension.
Pureté et documentation
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Fiche technique (285 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)