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Results for "

hepatoprotective+activity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) AMPK (2) Apoptosis (10) Aurora Kinase (2) Autophagy (2) Bacterial (3) Bcl-2 Family (2) Caspase (2) CDK (4) Chloride Channel (1) COX (1) Cryptochrome (2) Cytochrome P450 (3) Drug Derivative (2) Drug Metabolite (3) Endogenous Metabolite (3) Epigenetic Reader Domain (1) Fungal (1) FXR (3) HCV (1) HDAC (1) Interleukin Related (2) JNK (2) Keap1-Nrf2 (2) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) MMP (2) Monocarboxylate Transporter (1) NF-κB (5) NO Synthase (4) Oxidative Phosphorylation (2) p38 MAPK (1) PAK (1) Parasite (1) PARP (3) PPAR (2) Prolyl Endopeptidase (PREP) (2) Proteasome (2) Reactive Oxygen Species (ROS) (5) Reference Standards (9) Reverse Transcriptase (2) Ribosomal S6 Kinase (RSK) (2) Syk (2) Toll-like Receptor (TLR) (2) Tyrosinase (2) Xanthine Oxidase (2)
By Research Areas:	Cancer (22) Cardiovascular Disease (10) Endocrinology (1) Infection (7) Inflammation/Immunology (23) Metabolic Disease (27) Neurological Disease (6)

By Targets:

Akt (1)

AMPK (2)

Apoptosis (10)

Aurora Kinase (2)

Autophagy (2)

Bacterial (3)

Bcl-2 Family (2)

Caspase (2)

CDK (4)

Chloride Channel (1)

COX (1)

Cryptochrome (2)

Cytochrome P450 (3)

Drug Derivative (2)

Drug Metabolite (3)

Endogenous Metabolite (3)

Epigenetic Reader Domain (1)

Fungal (1)

FXR (3)

HCV (1)

HDAC (1)

Interleukin Related (2)

JNK (2)

Keap1-Nrf2 (2)

Microtubule/Tubulin (1)

Mitochondrial Metabolism (1)

MMP (2)

Monocarboxylate Transporter (1)

NF-κB (5)

NO Synthase (4)

Oxidative Phosphorylation (2)

p38 MAPK (1)

PAK (1)

Parasite (1)

PARP (3)

PPAR (2)

Prolyl Endopeptidase (PREP) (2)

Proteasome (2)

Reactive Oxygen Species (ROS) (5)

Reference Standards (9)

Reverse Transcriptase (2)

Ribosomal S6 Kinase (RSK) (2)

Syk (2)

Toll-like Receptor (TLR) (2)

Tyrosinase (2)

Xanthine Oxidase (2)

By Research Areas:

Cancer (22)

Cardiovascular Disease (10)

Endocrinology (1)

Infection (7)

Inflammation/Immunology (23)

Metabolic Disease (27)

Neurological Disease (6)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0823

Lithospermic acid 5+ Cited Publications (+)-Lithospermic acid	NO Synthase AMPK Keap1-Nrf2 Xanthine Oxidase Apoptosis	Cardiovascular Disease Inflammation/Immunology
Lithospermic acid ((+)-Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl₄)-induced acute liver damage in vitro and in vivo .

HY-N0462

Corilagin Maximum Cited Publications 8 Publications Verification NP-004255	Toll-like Receptor (TLR) Reverse Transcriptase Bacterial Apoptosis Autophagy	Infection Inflammation/Immunology Cancer
Corilagin, a gallotannin, has anti-tumor, anti-inflammatory and hepatoprotective activities. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin also inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows anti-tumor activity on hepatocellular carcinoma and ovarian cancer model. Corilagin shows low toxicity to normal cells and tissues .

HY-N2481

Oroxylin A-7-O-glucuronide 1 Publications Verification Oroxyloside; Oroxylin A-7-O-β-D-glucuronide	Prolyl Endopeptidase (PREP) Drug Metabolite JNK PPAR NF-κB Interleukin Related	Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Oroxylin A-7-O-glucuronide (oroxyloside) is an orally active flavonoid glucuronide and metabolite of Oroxylin A (HY-N0560). Oroxylin A-7-O-glucuronide can be extracted from the dried root of Scutellaria baicalensis. Oroxylin A-7-O-glucuronide exhibits prolyl oligopeptidase inhibitory activity. Oroxylin A-7-O-glucuronide inhibits the JNK pathway, upregulates PPARγ, and inhibits NF-κB p65 nuclear translocation. Oroxylin A-7-O-glucuronide reduces cytokine (IL-1β, IL-6) production. Oroxylin A-7-O-glucuronide exhibits anti-angiogenic, anti-tumor (glioma, liver cancer), anti-inflammatory, and hepatoprotective activities .

HY-N7056

4'-Hydroxychalcone 3 Publications Verification	Oxidative Phosphorylation Proteasome	Inflammation/Immunology Cancer
4'-Hydroxychalcone is a chalcone isolated from licorice root, with hepatoprotective activity. 4'-Hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition. 4'-Hydroxychalcone induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria .

HY-126052

Gnetol	COX Tyrosinase HDAC	Metabolic Disease Cancer
Gnetol is a phenolic compound isolated from the root of Gnetum montanum . Gnetol potently inhibits COX-1 (IC₅₀ of 0.78 μM) and HDAC. Gnetol is a potent tyrosinase inhibitor with an IC₅₀ of 4.5 μM for murine tyrosinase and suppresses melanin biosynthesis. Gnetol has antioxidant, antiproliferative, anticancer and hepatoprotective activity. Gnetol also possesses concentration-dependent α-Amylase, α-glucosidase, and adipogenesis activities .

HY-N2155

Tubuloside A 1 Publications Verification	Others	Metabolic Disease
Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity.

HY-N0805

Alisol B 23-acetate 3 Publications Verification 23-Acetylalismol B; 23-O-Acetylalisol B; Alisol B monoacetate	Apoptosis Reactive Oxygen Species (ROS) CDK MMP PARP FXR Syk	Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Alisol B 23-acetate is an orally active prototerpane-type triterpenoid. Alisol B 23-acetate can be isolated from Alisma orientalis. Alisol B 23-acetate induces Apoptosis, promotes ROS generation, downregulates CDK4/6, MMP-2/9, upregulates cleaved PARP, activates FXR and inhibits Syk. Alisol B 23-acetate has anti-inflammatory and hepatoprotective activities. Alisol B 23-acetate protects the kidney from ischemia-reperfusion injury. Alisol B 23-acetate has anticancer activity against ovarian cancer, colon cancer, lung cancer, and gastric cancer. Alisol B 23-acetate can be used in the study of atherosclerosis and allergic asthma .

HY-125911

Gossypin	NF-κB Aurora Kinase Ribosomal S6 Kinase (RSK) Apoptosis Caspase Bcl-2 Family PARP Cryptochrome	Cardiovascular Disease Inflammation/Immunology Cancer
Gossypin is an orally active flavone isolated from Hibiscus vitifolius. Gossypin has antioxidant, antiinflammatory, anticancer, anticataract, antidiabetic, and hepatoprotective activities. Gossypin inhibits NF-κB and NF-κB-regulated gene expression. Gossypin inhibits AURKA and RSK2. Gossypin inhibits invasion and induces apoptosis. Gossypin can be used for gastric cancer study .

HY-N2259

Curcumenol 4 Publications Verification (+)-Curcumenol	Cytochrome P450	Neurological Disease Inflammation/Immunology Cancer
Curcumenol ((+)-Curcumenol) is a potent CYP3A4 inhibitor with an IC₅₀ of 12.6 μM, which is one of constituents in the plants of medicinally important genus of Curcuma zedoaria, with neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. Curcumenol ((+)-Curcumenol) suppresses Akt-mediated NF-κB activation and p38 MAPK signaling pathway in LPS-stimulated BV-2 microglial cells .

HY-N7697B

Chitobiose dihydrochloride	Others	Others
Chitobiose dihydrochloride is an orally active chitosan oligosaccharide (degree of polymerization 2). Chitobiose dihydrochloride shows hepatoprotective activity and counteracts CCl₄-induced elevation of plasma aspartate transaminase and alanine transaminase activities in rats. Chitobiose dihydrochloride can be used for the research of carbon tetrachloride-induced acute hepatotoxicity .

HY-75625

2-Hydroxy-4-methoxybenzoic acid 4-Methoxysalicylic Acid	Monocarboxylate Transporter Apoptosis Mitochondrial Metabolism	Cardiovascular Disease Metabolic Disease Cancer
2-Hydroxy-4-methoxybenzoic acid is an orally active inhibitor of MCT-1 and MCT-4, as well as a plant biomarker. 2-Hydroxy-4-methoxybenzoic acid can be isolated from roots. 2-Hydroxy-4-methoxybenzoic acid induces Apoptosis and loss of mitochondrial membrane potential. 2-Hydroxy-4-methoxybenzoic acid exhibits anticancer activity against breast cancer. 2-Hydroxy-4-methoxybenzoic acid normalizes lactic acid levels. 2-Hydroxy-4-methoxybenzoic acid neutralizes viper venom and attenuates its lethal, hemorrhagic, coagulant and anticoagulant activities in male albino mice. 2-Hydroxy-4-methoxybenzoic acid possesses antihyperlipidemic, antidiabetic and hepatoprotective activities .

HY-N7697F

Chitobiose	Others	Metabolic Disease
Chitobiose is an orally active chitosan oligosaccharide (degree of polymerization 2). Chitobiose shows hepatoprotective activity and counteracts CCl₄-induced elevation of plasma aspartate transaminase and alanine transaminase activities in rats. Chitobiose can be used for the research of carbon tetrachloride-induced acute hepatotoxicity .

HY-N1506

Ganodermanontriol	Epigenetic Reader Domain p38 MAPK	Cancer
Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity .

HY-N2412

Irisolidone 1 Publications Verification	Chloride Channel	Neurological Disease Cancer
Irisolidone is a major isoflavone found in Pueraria lobata flowers. Irisolidone exhibits potent hepatoprotective activity. Irisolidone shows the high efficacy for volume-regulated anion channels (VRAC) blockade (IC₅₀=9.8 μM) .

HY-W068771

(E)-3-(4-Methoxyphenyl)acrylic acid	Endogenous Metabolite	Neurological Disease Metabolic Disease
(E)-3-(4-Methoxyphenyl)acrylic acid (compound 3) is isolated from Arachis hypogaea, Scrophularia buergeriana Miquel, Aquilegia vulgaris, Anigozanthos preissii and so on. (E)-3-(4-Methoxyphenyl)acrylic acid shows significant hepatoprotective activity, anti-amnesic, cognition-enhancing activity, antihyperglycemic, and neuroprotective activities .

HY-N0462R

Corilagin (Standard) NP-004255 (Standard)	Toll-like Receptor (TLR) Reference Standards Reverse Transcriptase Bacterial Apoptosis Autophagy	Infection Inflammation/Immunology Cancer
Corilagin (Standard) is the analytical standard of Corilagin. This product is intended for research and analytical applications. Corilagin, a gallotannin, has anti-tumor, anti-inflammatory and hepatoprotective activities. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin also inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows anti-tumor activity on hepatocellular carcinoma and ovarian cancer model. Corilagin shows low toxicity to normal cells and tissues .

HY-118383

Agathisflavone	Parasite	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities. Agathisflavone can improve tissue repair in a spinal cord injury model in rats .

HY-N11546

Sapindoside B	Cytochrome P450 Bacterial Fungal	Infection Cancer
Sapindoside B is a substance with hepatoprotective activity, and also acts as a cytochrome P-450 (cytochrome P-450) inhibitor, antibacterial agent and membrane-disrupting agent. Sapindoside B reversibly inhibits the content of cytochrome P-450 in liver microsomes, suppresses the phenobarbital-induced increase in enzyme content, reduces the production of active metabolites mediated by cytochrome P-450, and alleviates hepatotoxic injury. Sapindoside B binds to Cutibacterium acnes lipase, reduces lipase activity, inhibits biofilm formation, and decreases bacterial adhesion. Sapindoside B exhibits cytotoxicity against human cancer, liver cancer, leukemia and glioblastoma cells. Sapindoside B inhibits mycelial growth of phytopathogenic fungal strains, possesses antibacterial activity against dermatophytes, and also has hemolytic/membrane-lytic activity. Sapindoside B can be used in research related to liver injury, Cutibacterium acnes biofilm-associated infections, gastric cancer, carcinoma, promyelocytic leukemia, glioblastoma, apple scab and grape gray mold .

HY-146058

NF-κB/PON1-IN-1	NF-κB Reactive Oxygen Species (ROS)	Cancer
NF-κB/PON1-IN-1 (Compound 16) is a NF-κB/PON1 pathway inhibitor. NF-κB/PON1-IN-1 has antioxidant (IC₅₀ = 45.76 µM) and hepatoprotective activities .

HY-112575

Tiazotic acid	NO Synthase	Infection Cardiovascular Disease Inflammation/Immunology
Tiazotic acid is a metabolic agent that has immunomodulatory, anti-inflammatory, antioxidant, anti-ischemic, cardio- and endothelioprotective, antiplatelet, hepatoprotective activities. Tiazotic acid increases the levels of eNOS. Tiazotic acid also reduces the level of D-dimer in the blood, which reduces the risks of heart attacks and strokes in post-COVID syndrome .

HY-N2259R

Curcumenol (Standard) (+)-Curcumenol (Standard)	Reference Standards Cytochrome P450	Neurological Disease Inflammation/Immunology Cancer
Curcumenol ((+)-Curcumenol) is a potent CYP3A4 inhibitor with an IC50 of 12.6 μM, which is one of constituents in the plants of medicinally important genus of Curcuma zedoaria, with neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. Curcumenol ((+)-Curcumenol) suppresses Akt-mediated NF-κB activation and p38 MAPK signaling pathway in LPS-stimulated BV-2 microglial cells .

HY-125911R

Gossypin (Standard)	Reference Standards NF-κB Aurora Kinase Ribosomal S6 Kinase (RSK) Apoptosis Bcl-2 Family Caspase Cryptochrome	Cardiovascular Disease Inflammation/Immunology Cancer
Gossypin (Standard) is the analytical standard of Gossypin. This product is intended for research and analytical applications. Gossypin is an orally active flavone isolated from Hibiscus vitifolius. Gossypin has antioxidant, antiinflammatory, anticancer, anticataract, antidiabetic, and hepatoprotective activities. Gossypin inhibits NF-κB and NF-κB-regulated gene expression. Gossypin inhibits AURKA and RSK2. Gossypin inhibits invasion and induces apoptosis. Gossypin can be used for gastric cancer study.

HY-N2481R

Oroxylin A-7-O-glucuronide (Standard) Oroxyloside (Standard); Oroxylin A-7-O-β-D-glucuronide (Standard)	Reference Standards Prolyl Endopeptidase (PREP) Drug Metabolite JNK PPAR NF-κB Interleukin Related	Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Oroxylin A-7-O-glucuronide (Standard) is the analytical standard of Oroxylin A-7-O-glucuronide (HY-N2481). This product is intended for research and analytical applications. Oroxylin A-7-O-glucuronide (oroxyloside) is an orally active flavonoid glucuronide and metabolite of Oroxylin A (HY-N0560). Oroxylin A-7-O-glucuronide can be extracted from the dried root of Scutellaria baicalensis. Oroxylin A-7-O-glucuronide exhibits prolyl oligopeptidase inhibitory activity. Oroxylin A-7-O-glucuronide inhibits the JNK pathway, upregulates PPARγ, and inhibits NF-κB p65 nuclear translocation. Oroxylin A-7-O-glucuronide reduces cytokine (IL-1β, IL-6) production. Oroxylin A-7-O-glucuronide exhibits anti-angiogenic, anti-tumor (glioma, liver cancer), anti-inflammatory, and hepatoprotective activities .

HY-N12442

Sarmenoside III	Others	Metabolic Disease
Sarmenoside III is a flavonol glycoside with hepatoprotective activity isolated from Sedum sarmentosum.

HY-N10436

Anti-inflammatory agent 30	Others	Metabolic Disease Inflammation/Immunology
Anti-inflammatory agent 30 (Compound 5) is an anti-inflammatory agent with hepatoprotective activity .

HY-N2155R

Tubuloside A (Standard)	Reference Standards Others	Metabolic Disease
Tubuloside A (Standard) is the analytical standard of Tubuloside A. This product is intended for research and analytical applications. Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity.

HY-N1616

1β-Hydroxyeuscaphic acid	Apoptosis	Others
1β-Hydroxyeuscaphic acid has significant hepatoprotective activity by lowering the leakage of intracellular enzymes, reducing the oxidation of proteins and decreasing the incidence of apoptosis .

HY-121174

Alaternin Catharticin	NO Synthase CDK Tyrosinase Reactive Oxygen Species (ROS)	Metabolic Disease
Alaternin (Catharticin) is an anthraquinone compound with antioxidant and hepatoprotective activities. Alaternin has an inhibitory activity against hydroxyl radicals generated in a cell-free chemical system (FeSO₄/H₂O₂) with an IC₅₀ value of 3.05 μM. Alaternin exhibits hepatoprotective activity against Tacrine (HY-111338)-induced toxicity in human hepatic HepG2 cells with an EC₅₀ value of 4.02 μM .

HY-171857

Cytaphat	Reactive Oxygen Species (ROS)	Metabolic Disease Inflammation/Immunology
Cytaphat is a compound with hepatoprotective activity. Cytaphat has antioxidant, membrane-stabilizing and choleretic effects. Cytaphat can be used in the research of diseases such as acute toxic hepatopathy and liver injury .

HY-N12706

Heilaohuguosu G	Endogenous Metabolite	Endocrinology
Heilaohuguosu G (compound 7) is a cyclolignan with hepatoprotective activity. Heilaohuguosu G against APAP toxicity with cell survival rates at 10 μM of 45.7% in HepG-2 cells .

HY-N13159

Goodyeroside A	Others	Inflammation/Immunology
Goodyeroside A is a glycoside compound derived from the plant Goodyera that exhibits significant hepatoprotective activity. It can inhibit liver damage induced by carbon tetrachloride (HY-Y0298) in primary cultured rat hepatocytes .

HY-N11660

*weak Hepatoprotective* agent-1**	Others	Metabolic Disease
weak Hepatoprotective agent-1 (Compound 11) is a natural product that can be isolated from the fruits of Arctium lappa L.. weak Hepatoprotective agent-1 exhibits weak hepatoprotective activities at a concentration of 10 μM .

HY-N1324

Sanggenon N	Others	Others
Sanggenon N is an isoprenylated flavonoid that can be isolated from the root bark of Morus alba.Sanggenon N has hepatoprotective activities on t-BHP-induced cell cytotoxicity in HepG2 cells with an EC₅₀ of 23.45 μM .

HY-N15535

Cuneataside E	Others	Cancer
Cuneataside E is a phenylpropanoid glycoside compound found in Lespedeza cuneata. Cuneataside E exhibits hepatoprotective activity against the toxicity induced by N-acetyl-p-aminophenol (APAP) in the human hepatocellular carcinoma cell line HepG2. Cuneataside E is promising for research of liver diseases .

HY-N12072

3'-Methoxy-3,5,4'-trihydroxyflavone-7-neohesperidoside	Others	Others
3'-Methoxy-3,5,4'-trihydroxyflavone-7-neohesperidoside is a flavonoid that can be isolated from Cleome droserifolia. 3'-Methoxy-3,5,4'-trihydroxyflavone-7-neohesperidoside has moderate hepatoprotective activity ..

HY-N0823R

Lithospermic acid (Standard) (+)-Lithospermic acid (Standard)	Reference Standards NO Synthase AMPK Keap1-Nrf2 Xanthine Oxidase Apoptosis	Cardiovascular Disease Inflammation/Immunology
Lithospermic acid (Standard) is the analytical standard of Lithospermic acid. This product is intended for research and analytical applications. Lithospermic acid ((+)-Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl4)-induced acute liver damage in vitro and in vivo .

HY-W068771R

(E)-3-(4-Methoxyphenyl)acrylic acid (Standard)	Reference Standards Endogenous Metabolite	Neurological Disease Metabolic Disease
(E)-3-(4-Methoxyphenyl)acrylic acid (compound 3) is isolated from Arachis hypogaea, Scrophularia buergeriana Miquel, Aquilegia vulgaris, Anigozanthos preissii and so on. (E)-3-(4-Methoxyphenyl)acrylic acid shows significant hepatoprotective activity, anti-amnesic, cognition-enhancing activity, antihyperglycemic, and neuroprotective activities .

HY-N15155

Vitexin 7-O-β-D-glucopyranoside Vitexin 7-glucoside	Others	Metabolic Disease
Vitexin 7-O-β-D-glucopyranoside (Vitexin 7-glucoside) is a flavone glycoside found in Beta vulgaris var. cicla. Vitexin 7-O-β-D-glucopyranoside shows a hepatoprotective activity in primary cultured rat hepatocytes with Carbon tetrachloride (CCl4) (HY-Y0298)-induced cell toxicity .

HY-121989

cis-Trismethoxy resveratrol (Z)-3,5,4'-Trimethoxystilbene	Microtubule/Tubulin HCV CDK Akt PAK	Infection Metabolic Disease Cancer
cis-Trismethoxy resveratrol ((Z)-3,5,4'-Trimethoxystilbene) is an anti-HCV agent and Tubulin inhibitor, with an IC₅₀ of 4 μM against Tubulin. cis-Trismethoxy resveratrol induces G2/M phase cell cycle arrest, reduces DCLK1, decreases CDK1 levels, blocks phosphorylation of Akt Ser ⁴⁷³, and induces the expression of p21 ^Cip1/Waf1. cis-Trismethoxy resveratrol exhibits anti-tumor and hepatoprotective activities. cis-Trismethoxy resveratrol can be used in studies related to colon adenocarcinoma, hepatocellular carcinoma, hepatitis C, and liver injury .

HY-N0805R

Alisol B 23-acetate (Standard) 23-Acetylalismol B (Standard); 23-O-Acetylalisol B (Standard); Alisol B monoacetate (Standard)	Reference Standards Apoptosis Reactive Oxygen Species (ROS) CDK MMP PARP FXR Syk	Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Alisol B 23-acetate (Standard) is the analytical standard of Alisol B 23-acetate (HY-N0805). This product is intended for research and analytical applications. Alisol B 23-acetate is an orally active prototerpane-type triterpenoid. Alisol B 23-acetate can be isolated from Alisma orientalis. Alisol B 23-acetate induces Apoptosis, promotes ROS generation, downregulates CDK4/6, MMP-2/9, upregulates cleaved PARP, activates FXR and inhibits Syk. Alisol B 23-acetate has anti-inflammatory and hepatoprotective activities. Alisol B 23-acetate protects the kidney from ischemia-reperfusion injury. Alisol B 23-acetate has anticancer activity against ovarian cancer, colon cancer, lung cancer, and gastric cancer. Alisol B 23-acetate can be used in the study of atherosclerosis and allergic asthma .

HY-N10435

Anti-inflammatory agent 29	Others	Metabolic Disease Inflammation/Immunology
Anti-inflammatory agent 29 (Compound 7) is an anti-inflammatory agent with hepatoprotective activity .

HY-N10434

Anti-inflammatory agent 28	Others	Metabolic Disease Inflammation/Immunology
Anti-inflammatory agent 28 (Compound 9) is an anti-inflammatory agent with hepatoprotective activity .

HY-N17412

Chrysandroside A	Others	Metabolic Disease
Chrysandroside A is a flavanonol glycoside found in Gordonia chrysandra Cowan. Chrysandroside A shows hepatoprotective activity .

HY-N17630

Schekwangsienin	Others	Metabolic Disease
Schekwangsienin is a triterpenoid compound isolated from the aerial parts of Schefflera kwangsiensis. Schekwangsienin exhibits hepatoprotective activity and can be used in studies on liver injury .

HY-N17467

Forsydoitriside A	Drug Derivative	Metabolic Disease
Forsydoitriside A is an iridoid glycoside trimer found in the fruits of Forsythia suspensa. Forsydoitriside A shows no significant hepatoprotective activity against Acetaminophen (HY-66005)-induced damage in liver cells at 10 μM .

HY-N18019

Tetrahydro bellidifolin	Drug Metabolite	Metabolic Disease
Tetrahydro bellidifolin (Compound 1a) is the aglycone obtained from the hydrolysis of Tetrahydroswertianolin (HY-N18018) by β-glucosidase. Tetrahydro bellidifolin exhibits significant hepatoprotective activity and reduce serum ALT levels. Tetrahydro bellidifolin can be used for the research of liver injury .

HY-N17767

Leonoside F	Others	Inflammation/Immunology
Leonoside F is a phenylethanoid glycoside compound isolated from the aerial parts of Leonurus japonicus Houtt., which protects liver cells from chemically induced damage. At a concentration of 1×10 ^-5 M, Leonoside F shows significant hepatoprotective activity against D-galactosamine-induced damage in HL-7702 liver cells, with an inhibition rate of 30.9% .

HY-181761

FXR agonist 16	FXR	Metabolic Disease
FXR agonist 16 is a FXR agonist with an EC₅₀ of 2.2 μM. FXR agonist 16 activates FXR transcriptional activity, upregulates SHP and BSEP, and downregulates Cyp7a1. FXR agonist 16 exhibits hepatoprotective activity and reduces AST and ALT levels in free fatty acid-induced hepatocellular injury models. FXR agonist 16 can be used for the research of liver injury .

HY-N6998A

6-epi-Paederosidic acid	Others	Infection Cancer
6-epi-Paederosidic acid is a cyclopentanoid monoterpene glycoside found in the aerial parts of Paederia foetida L. 6-epi-Paederosidic acid does not exhibit cytotoxic activity against human tumor cells, hepatoprotective activity against APAP (HY-66005)-induced cellular toxicity, or inhibitory activity against LPS (HY-D1056)-induced nitric oxide production in murine microglia .

HY-N7056R

4'-Hydroxychalcone (Standard)	Reference Standards Proteasome Oxidative Phosphorylation	Inflammation/Immunology Cancer
4'-Hydroxychalcone (Standard) is the analytical standard of 4'-Hydroxychalcone (HY-N7056). This product is intended for research and analytical applications. 4'-Hydroxychalcone is a chalcone isolated from licorice root, with hepatoprotective activity. 4'-Hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition. 4'-Hydroxychalcone induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria .

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hepatoprotective+activity

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