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  3. Gossypin

Gossypin 

Cat. No.: HY-125911
Handling Instructions

Gossypin is a flavone isolated from Hibiscus vitifolius and has antioxidant, antiinflammatory, anticancer, anticataract, antidiabetic, analgesic and hepatoprotective activities. Gossypin inhibits NF-κB and NF-κB-regulated gene expression. Gossypin inhibits RANKL-induced osteoclastogenesis both in mouse primary bone marrow cells and RAW 264.7 cells in vitro.

For research use only. We do not sell to patients.

Gossypin Chemical Structure

Gossypin Chemical Structure

CAS No. : 652-78-8

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Description

Gossypin is a flavone isolated from Hibiscus vitifolius and has antioxidant, antiinflammatory, anticancer, anticataract, antidiabetic, analgesic and hepatoprotective activities. Gossypin inhibits NF-κB and NF-κB-regulated gene expression. Gossypin inhibits RANKL-induced osteoclastogenesis both in mouse primary bone marrow cells and RAW 264.7 cells in vitro[1][2].

IC50 & Target

IC50: NF-κB[1]

Molecular Weight

480.38

Formula

C₂₁H₂₀O₁₃

CAS No.

652-78-8

SMILES

O=C1C(O)=C(C2=CC=C(O)C(O)=C2)OC3=C(O[[email protected]]4[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]@H](CO)O4)O)O)O)C(O)=CC(O)=C13

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

GossypinNF-κBNuclear factor-κBNuclear factor-kappaBAntiinflammatoryAnticancerAnalgesicAntiallergicAntiviralAntioxidantcardiovascular,osteoclastogenesisInhibitorinhibitorinhibit

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