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Results for "

solani

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetyl-CoA Carboxylase (1) Antibiotic (7) Apoptosis (2) ATP Synthase (1) Bacterial (13) Biochemical Assay Reagents (3) Caspase (3) Constitutive Androstane Receptor (2) Cytochrome P450 (3) Dihydrofolate reductase (DHFR) (1) Drug Derivative (1) EGFR (1) Endogenous Metabolite (5) Environmental Pollutants (6) Fungal (90) Herbicide (2) HIV (1) Insecticide (2) Isotope-Labeled Compounds (2) Keap1-Nrf2 (1) Microtubule/Tubulin (1) Mitochondrial Metabolism (5) MMP (1) Myosin (1) NF-κB (2) Parasite (3) PARP (1) Pregnane X Receptor (PXR) (1) Pyruvate Kinase (1) Reactive Oxygen Species (ROS) (3) Reference Standards (4) Succinate Dehydrogenase (21) Tyrosinase (1)
By Research Areas:	Cancer (7) Infection (91) Inflammation/Immunology (7) Metabolic Disease (1) Neurological Disease (1)

By Targets:

Acetyl-CoA Carboxylase (1)

Antibiotic (7)

Apoptosis (2)

ATP Synthase (1)

Bacterial (13)

Biochemical Assay Reagents (3)

Caspase (3)

Constitutive Androstane Receptor (2)

Cytochrome P450 (3)

Dihydrofolate reductase (DHFR) (1)

Drug Derivative (1)

EGFR (1)

Endogenous Metabolite (5)

Environmental Pollutants (6)

Fungal (90)

Herbicide (2)

HIV (1)

Insecticide (2)

Isotope-Labeled Compounds (2)

Keap1-Nrf2 (1)

Microtubule/Tubulin (1)

Mitochondrial Metabolism (5)

MMP (1)

Myosin (1)

NF-κB (2)

Parasite (3)

PARP (1)

Pregnane X Receptor (PXR) (1)

Pyruvate Kinase (1)

Reactive Oxygen Species (ROS) (3)

Reference Standards (4)

Succinate Dehydrogenase (21)

Tyrosinase (1)

By Research Areas:

Cancer (7)

Infection (91)

Inflammation/Immunology (7)

Metabolic Disease (1)

Neurological Disease (1)

102

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2524

Camelliaside A	EGFR	Cancer
Camelliaside A is a phytochemical and also a HER2 ligand. Camelliaside A shows no inhibitory effect on mycelial growth of Rhizoctonia solani, indicating no antifungal activity against this pathogen. Camelliaside A is applicable to breast cancer-related research .

HY-119459

Fluopyram 1 Publications Verification	Environmental Pollutants Constitutive Androstane Receptor Parasite Caspase Fungal NF-κB Succinate Dehydrogenase Pregnane X Receptor (PXR)	Infection Cancer
Fluopyram is an orally active succinate dehydrogenase inhibitor, antifungal and nematicide. Fluopyram inhibits succinate dehydrogenase activity, activates CAR/PXR nuclear receptors, and increases caspase-3, TNF-α and NF-κB. Fluopyram inhibits the growth of F. virguliforme, Botrytis cinerea and Alternaria solani with EC₅₀ values of 3.35, 5.389 and 0.244 µg/mL, respectively. Fluopyram induces liver and thyroid tumor formation. Fluopyram is nephrotoxic and embryotoxic .

HY-W004263

1-Eicosanol Arachidyl alcohol	Environmental Pollutants Fungal	Infection
1-Eicosanol (Arachidyl alcohol) is a long-chain fatty alcohol and volatile organic compound that can be isolated from the leaves of Leea indica and produced by Bacillus velezensis ZJ1. 1-Eicosanol inhibits mycelial growth of Alternaria solani and Botrytis cinerea. 1-Eicosanol is applicable to research related to tomato early blight and tomato gray mold .

HY-B0856

Validamycin A 1 Publications Verification	Fungal Tyrosinase Antibiotic	Infection
Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1?μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC₅₀ of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a K_i of 5.893 mM .

HY-17520

Penthiopyrad 1 Publications Verification MTF-753	Environmental Pollutants Fungal	Infection
Penthiopyrad (MTF-753) is a carboxamide Fungicide. Penthiopyrad inhibits SDH. Penthiopyrad exhibits broad-spectrum antifungal activity, being effective not only against Basidiomycetes, but also against Ascomycetes and Deuteromycetes. Penthiopyrad inhibits the mycelial growth of Alternaria mali, Botrytis cinerea, Monilinia mali, Rhizoctonia solani and Sclerotinia sclerotiorum on PDA medium, with EC₅₀ values ranging from <0.4 ppm to 0.34 ppm and MIC values ranging from 6.6 ppm to 47.9 ppm .

HY-N1970

5,7-Dihydroxychromone 2 Publications Verification	Keap1-Nrf2 Caspase PARP Fungal	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
5,7-Dihydroxychromone is a flavonoid compound with antioxidant properties. 5,7-Dihydroxychromone induces Nrf2 nuclear translocation, increases Nrf2/ARE binding activity, and up-regulates Nrf2-dependent antioxidant genes HO-1, NQO1, GCLc. 5,7-Dihydroxychromone attenuates excessive ROS generation, inhibits activated caspase-3, caspase-9, cleaved PARP expression, and prevents neuronal apoptosis and cell death. 5,7-Dihydroxychromone increases LXRα and PPARγ mRNA expression, induces preadipocyte differentiation, and regulates blood glucose levels. 5,7-Dihydroxychromone inhibits radial growth of soil pathogenic fungi, radicle elongation of select seedlings, and transiently inhibits Bradyrhizobium sp. growth in high mannitol medium. 5,7-Dihydroxychromone can be used for the research of Parkinson’s disease, type 2 diabetes mellitus and pathogenic fungal infection .

HY-B2011

Flutolanil	Environmental Pollutants Succinate Dehydrogenase Fungal Mitochondrial Metabolism	Infection
Flutolanil is a succinate dehydrogenase complex inhibitor and fungicide. Flutolanil blocks electron transfer between the redox center of succinate dehydrogenase and coenzyme Q, inhibits mycelial oxygen consumption, and suppresses mycelial growth. Flutolanil induces acute and sublethal toxicity in zebrafish at different life stages. Flutolanil can be used in studies on plant disease control .

HY-W015343

3-Methoxyphenylacetic acid m-Methoxyphenylacetic acid	Endogenous Metabolite	Others
3-Methoxyphenylacetic acid (m-Methoxyphenylacetic acid), a m-hydroxyphenylacetic acid (m-OHPAA) derivative, is a phytotoxin in Rhizoctonia solani. 3-Methoxyphenylacetic acid is used to develop a toxin-mediated bioassay for resistance to rhizoctonia root rot .

HY-119459R

Fluopyram (Standard)	Reference Standards Succinate Dehydrogenase Fungal Parasite Constitutive Androstane Receptor Caspase NF-κB	Infection Cancer
Fluopyram (Standard) is the analytical standard of Fluopyram (HY-119459). This product is intended for research and analytical applications. Fluopyram is an orally active succinate dehydrogenase inhibitor, antifungal and nematicide. Fluopyram inhibits succinate dehydrogenase activity, activates CAR/PXR nuclear receptors, and increases caspase-3, TNF-α and NF-κB. Fluopyram inhibits the growth of F. virguliforme, Botrytis cinerea and Alternaria solani with EC₅₀ values of 3.35, 5.389 and 0.244 µg/mL, respectively. Fluopyram induces liver and thyroid tumor formation. Fluopyram is nephrotoxic and embryotoxic .

HY-B2053

Tolclofos-methyl	Fungal	Infection
Tolclofos-methyl is an organophosphorus fungicide. Tolclofos-methyl undergoes photoinduced oxidative degradation to form oxo-analog derivatives. Tolclofos-methyl inhibits spore division in fungi and oomycetes, induces cytoplasmic leakage, and interferes with flagellar movement. Tolclofos-methyl is rapidly metabolized and excreted in rodents. Tolclofos-methyl can be used in studies related to fungal infections .

HY-123351

Kievitone	Fungal	Infection Cancer
Kievitone, an isoflavanone, could be isolated from hypocotyls of Phaseolus vulgaris L. infected with Rhizoctonia solani* Kühn*. Kievitone has antifungal activity and antitumor activity .

HY-133719

Fenfuram	Fungal	Infection
Fenfuram is an antifungal agent with an EC₅₀ of 6.18 mg/mL against R. solani. Fenfuram can be used in anti-infective research .

HY-N6625S

Chlorothalonil-13C2	Fungal	Inflammation/Immunology
Chlorothalonil- ¹³C₂ is the ¹³C-labeled Chlorothalonil. Chlorothalonil is a broad spectrum fungicide and is effective in protecting plants against fungal diseases caused mainly by Phytophthora infestans and Alternaria solani. Chlorothalonil is used for controlling of fungal foliar diseases of vegetables and crops .

HY-169972

Succinate dehydrogenase-IN-5	Succinate Dehydrogenase	Infection
Succinate dehydrogenase-IN-5 (Compound M8) is the inhibitor for succinate dehydrogenase. Succinate dehydrogenase-IN-5 interfers with the energy metabolism and growth of fungi, inhibits Rhizoctonia solani, Sclerotinia sclerotiorum, Botrytis cinerea and Fusarium graminearum with EC₅₀ < 0.3 μg/mL .

HY-149876

SDH-IN-5	Fungal	Infection
SDH-IN-5 (compound 7d) is a potent succinate dehydrogenase (SDH) inhibitor, with an IC₅₀ of 3.293 μM. SDH-IN-5 is also exhibits antifungal activity, with an EC₅₀ of 0.046 μg/mL against R. solani. SDH-IN-5 could significantly inhibit the growth of R. solani in rice leaves with excellent protective and curative efficacies .

HY-W150903

N-Heptyl 4-hydroxybenzoate p-Oxybenzoesaureheptylester	Fungal Bacterial	Infection
N-Heptyl 4-hydroxybenzoate (p-Oxybenzoesaureheptylester) is an antimicrobial agent that inhibits S. aureus with MIC of 12.5 μg/mL. N-Heptyl 4-hydroxybenzoate also against plant pathogenic fungi, such as Alternaria brassicicola, F. solani, C. dematium and C. acutatum .

HY-N12167

3-epi-Bufalin	Others	Others
3-epi-Bufalin (compound 2a) is the microbial transformation product of bufadienolide .

HY-129316

(S)-Dihydroaeruginoic acid CGP 52547	Antibiotic Fungal Bacterial	Infection
(S)-Dihydroaeruginoic acid is an antibiotic originally isolated from P. fluorescens. It has antimicrobial activity in a disc assay against R. solani, P. ultimum, B. cinera, S. rolfsii, C. gloeosporioide, F. oxysporum, and S. tritici fungi as well as B. subtilis, E. herbicola, and S. albus bacteria when used at a concentration of 200 μg/disc.

HY-168446

PKR-IN-1	Pyruvate Kinase Fungal	Infection
PKR-IN-1 (Compound 5s) is a pyruvate kinase (PK) inhibitor that has antifungal activity, with an EC₅₀ of 0.21 μg/mL for R. solani .

HY-178799

SDH-IN-37	Succinate Dehydrogenase Fungal	Infection
SDH-IN-37 (Compound A37) is a potent SDH inhibitor, with an IC₅₀ value of 0.0263 μM. SDH-IN-37 is also an antifungal agent. SDH-IN-37 demonstrates antifungal activities against Rhizoctonia solani, S. sclerotiorum and F. graminearum, with EC₅₀ values of 0.0144, 0.882 and 1.99 μg/mL, respectively .

HY-142912

Stemphyperylenol	Fungal	Others
Stemphyperylenol displays a potent antifungal activity against the plant pathogen Alternaria solani with MIC of 1.57 μM.

HY-163634

YZK-C22	Fungal	Infection
YZK-C22, containing a 1,2,3-thiadiazol-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole skeleton, is a fungicide lead compound with broad-spectrum fungicidal activity .

HY-W099582

Myristamidopropyl dimethylamine Lexamine M-13; MAPD	Environmental Pollutants Antibiotic Biochemical Assay Reagents Bacterial Fungal Insecticide	Inflammation/Immunology
Myristamidopropyl dimethylamine (MAPD) is an antimicrobial agent (including against bacteria and fungi) and an insecticide, exhibiting inhibitory activity against Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans, Fusarium solani, and Acanthamoeba polyphaga. Myristamidopropyl dimethylamine can be used in research on microbial-induced keratitis .

HY-149323

SDH-IN-4	Fungal	Infection
SDH-IN-4 (compound B6) is a selective inhibitor against succinate dehydrogenase (SDH) with an IC₅₀ value of 0.28 μg/mL. SDH-IN-4 has highly efficient and broad-spectrum antifungal activity, against R. solani with an EC₅₀ value of 0.23 μg/mL .

HY-178801

SDH-IN-39	Succinate Dehydrogenase Fungal	Infection
SDH-IN-39 (Compound A16) is a SDH inhibitor, with an IC₅₀ value of 6.83 μg/mL. SDH-IN-39 is also an antifungal agent. SDH-IN-39 shows antifungal activity against Rhizoctonia solani (EC₅₀ of 1.49 μg/mL), G. zeae, C. gloeosporioides, S. sclerotiorum and M. oryzae .

HY-178778

SDH-IN-38	Fungal	Infection
SDH-IN-38 (Compound IIIe) is a Succinate dehydrogenase inhibitor. SDH-IN-38 is an antifungal agent, with an EC₅₀ value of 0.009 μg/mL against R. solani mycelia. SDH-IN-38 inhibits mycelial growth by affecting mycelial respiration. SDH-IN-38 induces cellular senescenc and reduces mitochondrial membrane potential in mycelia .

HY-P11176

Coccinin	Fungal HIV	Infection
Coccinin is an antifungal peptide. Coccinin can be purified from the seeds of large scarlet runner beans. Coccinin inhibits HIV-1 reverse transcriptase. Coccinin shows antifungal activity against M. arachidicola, F. oxysporum, P. piricola, B. cinerea, C. comatus and R. solani, with IC₅₀s of 75, 81, 89, 109, 122 and 134 μM, respectively .

HY-148054

Antifungal agent 36	Fungal	Infection
Antifungal agent 36 is a potent anti-fungal agent. Antifungal agent 36 shows anti-fungal activity for Basidiomycetes .

HY-121178

Deoxyviolacein	Bacterial Fungal	Infection
Deoxyviolacein is a bacterial metabolite and byproduct in the biosynthesis of the bisindole alkaloid violacein (HY-119809) that has anticancer, antibacterial, and antifungal properties. It inhibits proliferation of hepatocellular carcinoma cells when used at concentrations ranging from 0.1 to 1 μM. Deoxyviolacein (125 μg/mL) has antibacterial activity against Gram-positive bacteria, including S. aureus, B. subtilis, and B. megaterium. It also has antifungal activity against R. solani when used at a concentration of 2 mg/ml.

HY-W150903S

N-Heptyl 4-hydroxybenzoate-d4 p-Oxybenzoesaureheptylester [German]-d₄	Isotope-Labeled Compounds Fungal Bacterial	Infection
N-Heptyl 4-hydroxybenzoate-d₄ is the deuterium labeled N-Heptyl 4-hydroxybenzoate (HY-W150903) . N-Heptyl 4-hydroxybenzoate (p-Oxybenzoesaureheptylester) is an antimicrobial agent that inhibits S. aureus with MIC of 12.5 μg/mL. N-Heptyl 4-hydroxybenzoate also against plant pathogenic fungi, such as Alternaria brassicicola, F. solani, C. dematium and C. acutatum .

HY-178162

CYP51-IN-27	Fungal Cytochrome P450	Infection
CYP51-IN-27 is a sterol 14α-demethylase CYP51 inhibitor with an IC₅₀ of 0.3434 μg/mL. CYP51-IN-27 exhibits antifungal activity and inhibits the production of fungal ergosterol. CYP51-IN-27 can be used for the research of infection, such as rice sheath blight .

HY-158053

Antifungal agent 94	Fungal	Infection
Antifungal agent 94 (Compound 49) is a Flavonoid derivative, which exhibits antifungal activity with EC₅₀ of 0.28 μM and a half-maximal effective concentration of 0.46 μg/mL against Rhizoctonia solani .

HY-172363

Succinate dehydrogenase-IN-6	Succinate Dehydrogenase Fungal	Infection
Succinate dehydrogenase-IN-6 (Compound E23) is the inhibitor for succinate dehydrogenase that inhibits SDH in Rhizoctonia solani with an IC₅₀ of 11.76 μM. Succinate dehydrogenase-IN-6 disrupts fungal cell membrane, exhibits board-spectrum antifungal activity that inhibits R. solani, V. dahliae, A. solani and C. gloeosporioides with EC₅₀s of 0.41, 0.27, 1.15, 0.27 μg/mL, respectively. Succinate dehydrogenase-IN-6 exhibits no significant toxicity in rice and zebrafish (LC₅₀ > 12.5 μg/mL) .

HY-161010

DHFR-IN-13	Dihydrofolate reductase (DHFR)	Infection
DHFR-IN-13 (Compd Hit8) is an active R. solani DHFR inhibitor with an IC₅₀ value of 10.2 μM. DHFR-IN-13 has selectivity of inhibition against human DHFR with an IC₅₀ value of 227.7 μM. DHFR-IN-13 also is a fungicide. DHFR-IN-13 has high antifungal activity against R. solani with EC₅₀ value of 38.2 mg/L .

HY-172222

Antifungal agent 127	Fungal	Infection
Antifungal agent 127 (Compound 6c) is an antifungal agent. Antifungal agent 127 exhibits strong inhibitory activity against Botrytis cinerea, Rhizoctonia solani, and other fungi .

HY-169069

Antifungal agent 110	Fungal	Infection
Antifungal agent 110 exhibits fungicidal activity toward Botrytis cinerea and Rhizoctonia solani. Antifungal agent 110 displays antifungal activity against R. solani with an EC₅₀ value of 0.27 mg/L. Antifungal agent 110 is promising for research of plant diseases .

HY-174456

Succinate dehydrogenase-IN-10	Succinate Dehydrogenase Fungal	Infection
Succinate dehydrogenase-IN-10 (Compound B5) is a RsSDH (Succinate dehydrogenase of R. solani) inhibitor with an IC₅₀ of 0.12 μM. Succinate dehydrogenase-IN-10 exhibits antifungal activity against R. solani (EC₅₀ of 0.002 μg/mL) and P. pachyrhizi .

HY-175501

Succinate dehydrogenase-IN-11	Fungal Succinate Dehydrogenase	Infection
Succinate dehydrogenase-IN-11 (Compound A12) is a succinate dehydrogenase inhibitor with an IC₅₀ value of 3.58 μM. Succinate dehydrogenase-IN-11 exhibits antifungal activity. Succinate dehydrogenase-IN-11 shows activity against fungi such as R. solani, B. cinerea, F. graminearum, and S. sclerotiorum in vitro. Succinate dehydrogenase-IN-11 also exerts a controlling effect on R. solani, P. pachyrhizi, and P. sorghi in vivo. Succinate dehydrogenase-IN-11 can be used in research related to antifungal applications .

HY-N10289

Cytosporone C	Fungal	Infection
Cytosporone C is an antifungal metabolite from the Melia azedarach-Associated Fungus Diaporthe eucalyptorum. Cytosporone C exhibits antifungal activities against Alternaria solani .

HY-158980

Antifungal agent 103	Fungal Bacterial	Infection
Antifungal agent 103 (compound 7y) is a potent antifungal agent. Antifungal agent 103 inhibits R. solani with an EC₅₀ of 0.47 μg/mL .

HY-159486

SDH-IN-18	Succinate Dehydrogenase Fungal	Infection
SDH-IN-18 (Compound 3a) is an inhibitor for succinate dehydrogenase (SDH) with an IC₅₀ of 8.70 mg/L. SDH-IN-18 destroys fungal morphology and reproduction, exhibits antifungal activity against Rhizoctonia solani and Sclerotinia sclerotiorum with EC₅₀ of 0.48 and 1.4 mg/L .

HY-163397

Antibacterial agent 196	Fungal	Infection
Antibacterial agent 196 (compound 6b) is a coumarin derivative containing oxime ether structure, and shows antifungal activity, with the EC₅₀ of 0.46 μg/mL against Rhizoctonia solani .

HY-W164451

N-(2-hydroxy-2-phenylethyl)acetamide	Fungal	Infection
N-(2-hydroxy-2-phenylethyl)acetamide is isolated from the solid rice cultures of the endophytic fungus Diaporthe eucalyptorum KY-9. N-(2-hydroxy-2-phenylethyl)acetamide exhibits antifungal activities against Alternaria solani .

HY-155703

LW3	Fungal	Infection
LW3 is a potent antifungal agent. LW3 has antifungal activity with EC₅₀ values of 0.54, 0.09, 1.52, and 2.65 mg/L against B. cinerea, R. solani, S. sclerotiorum, and F. graminearum, respectively .

HY-163693

Antifungal agent 104	Fungal	Infection
Antifungal agent 104 (Compound 5e) exhibits antifungal activity against Sclerotinia sclerotiorum, Rhizoctonia solani and Botrytis cinerea, with EC₅₀ of 1.52 μg/mL, 0.06 μg/mL and 15.69 μg/mL, respectively. Antifungal agent 104 exhibits low cytotoxicity to human renal cell 239A (6.28-100 mM) .

HY-163890

Succinate dehydrogenase-IN-2	Succinate Dehydrogenase Parasite	Infection
Succinate dehydrogenase-IN-2 (Compound 12x) is an inhibitor for succinate dehydrogenase (SDH) with an IC₅₀ of 1.22 mg/L. Succinate dehydrogenase-IN-2 exhibits antifungal activity, that inhibits S. sclerotiorum, V. mali, G. graminis, R. solani and B. cinerea with EC₅₀ of 0.52-3.42 mg/L .

HY-162559

SDH-IN-16	Fungal	Infection
SDH-IN-16 (compound 5aa) is a potent inhibitor of Succinate Dehydrogenase, with the IC₅₀ of 1.62 μM. SDH-IN-16 displays a broad spectrum of antifungal activity against F. graminearum, B. cinerea, S. sclerotiorum, and R. solani, with the corresponding EC₅₀ values of 0.12, 4.48, 0.33, and 0.15 μg/mL, respectively .

HY-172810

Succinate dehydrogenase-IN-8	Succinate Dehydrogenase Fungal	Infection
Succinate dehydrogenase-IN-8 (compound i19) is a potent succinate dehydrogenase (SDH) inhibitor. Succinate dehydrogenase-IN-8, an indene amino acid derivative, demonstrates potent in vitro antifungal activity against Rhizoctonia solani (EC₅₀=0.1843 mg/L), Botrytis cinerea (EC₅₀=0.4829 mg/L), and Sclerotinia sclerotiorum (EC₅₀=0.1349 mg/L) .

HY-N12475

Solavetivone	Fungal Cytochrome P450	Infection
Solavetivone is a Sesquiterpenoid phytoalexin and Antifungal agent. Solavetivone is isolated from stress-challenged potato plants. Solavetivone is hydroxylated by sesquiterpenoid phytoalexin hydroxylase (SPH/CYP76A2L). Solavetivone helps solanaceous plants defend against pathogens, damages plant cells after pathogen threat, and inhibits mycelial growth of Rhizoctonia solani. Solavetivone is applicable to studies related to Rhizoctonia solani infection .

HY-162648

Succinate dehydrogenase-IN-1	Fungal	Infection
Succinate dehydrogenase-IN-1 (Compound 34) is an inhibitor for succinate dehydrogenase (SDH) with an IC₅₀ of 0.94 μM and a K_D of 22.4 μM. Succinate dehydrogenase-IN-1 exhibits antifungal activity against Rhizoctonia solani, Sclerotinia sclerotiorum, Monilinia fructicola, and Botrytis cinerea, with EC₅₀ of 0.04 μM, 1.13 μM, 1.61 μM and 1.21 μM, respectively .

Cat. No.	Product Name	Type

HY-W116336B

Zinc oxide, 99.99% metals basis

Biochemical Assay Reagents

Zinc oxide, 99.99% metals basis is a versatile wide-bandgap semiconductor with superior comprehensive properties. Zinc oxide, 99.99% metals basis serves as raw material for Schottky diodes, functional nanostructures, sensors, energy harvesters and photocatalysts for hydrogen production. Zinc oxide, 99.99% metals basis acts as a non-toxic antibacterial agent and selective cytotoxin against multiple bacteria, fungi and spores. Zinc oxide, 99.99% metals basis induces cancer cell death. Zinc oxide, 99.99% metals basis is applicable to drug delivery, biosensing, bioimaging and researches on cancer, microbial infections and skin diseases .

Cat. No.	Product Name	Target	Research Area

HY-P11176

Coccinin	Fungal HIV	Infection
Coccinin is an antifungal peptide. Coccinin can be purified from the seeds of large scarlet runner beans. Coccinin inhibits HIV-1 reverse transcriptase. Coccinin shows antifungal activity against M. arachidicola, F. oxysporum, P. piricola, B. cinerea, C. comatus and R. solani, with IC₅₀s of 75, 81, 89, 109, 122 and 134 μM, respectively .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2524

Camelliaside A	Flavonols Structural Classification Flavonoids Classification of Application Fields Phenols Polyphenols Camellia sinensis (L.) O. Ktze. Plants Inflammation/Immunology Disease Research Fields Source Classification Theaceae	EGFR
Camelliaside A is a phytochemical and also a HER2 ligand. Camelliaside A shows no inhibitory effect on mycelial growth of Rhizoctonia solani, indicating no antifungal activity against this pathogen. Camelliaside A is applicable to breast cancer-related research .

HY-W004263

1-Eicosanol Arachidyl alcohol	Structural Classification Natural Products other families Classification of Application Fields Plants Hypericum carinatum Inflammation/Immunology Disease Research Fields Source Classification	Environmental Pollutants Fungal
1-Eicosanol (Arachidyl alcohol) is a long-chain fatty alcohol and volatile organic compound that can be isolated from the leaves of Leea indica and produced by Bacillus velezensis ZJ1. 1-Eicosanol inhibits mycelial growth of Alternaria solani and Botrytis cinerea. 1-Eicosanol is applicable to research related to tomato early blight and tomato gray mold .

HY-B0856

Validamycin A 1 Publications Verification	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Fungal Tyrosinase Antibiotic
Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1?μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC₅₀ of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a K_i of 5.893 mM .

HY-N1970

5,7-Dihydroxychromone 2 Publications Verification	Structural Classification Flavonoids other families Phenols Polyphenols Plants Isoflavones Source Classification	Keap1-Nrf2 Caspase PARP Fungal
5,7-Dihydroxychromone is a flavonoid compound with antioxidant properties. 5,7-Dihydroxychromone induces Nrf2 nuclear translocation, increases Nrf2/ARE binding activity, and up-regulates Nrf2-dependent antioxidant genes HO-1, NQO1, GCLc. 5,7-Dihydroxychromone attenuates excessive ROS generation, inhibits activated caspase-3, caspase-9, cleaved PARP expression, and prevents neuronal apoptosis and cell death. 5,7-Dihydroxychromone increases LXRα and PPARγ mRNA expression, induces preadipocyte differentiation, and regulates blood glucose levels. 5,7-Dihydroxychromone inhibits radial growth of soil pathogenic fungi, radicle elongation of select seedlings, and transiently inhibits Bradyrhizobium sp. growth in high mannitol medium. 5,7-Dihydroxychromone can be used for the research of Parkinson’s disease, type 2 diabetes mellitus and pathogenic fungal infection .

HY-W015343

3-Methoxyphenylacetic acid m-Methoxyphenylacetic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Disease Research Fields Source Classification	Endogenous Metabolite
3-Methoxyphenylacetic acid (m-Methoxyphenylacetic acid), a m-hydroxyphenylacetic acid (m-OHPAA) derivative, is a phytotoxin in Rhizoctonia solani. 3-Methoxyphenylacetic acid is used to develop a toxin-mediated bioassay for resistance to rhizoctonia root rot .

HY-N14257

Andrimid	Structural Classification Natural Products Microorganisms Source Classification	Bacterial Antibiotic Acetyl-CoA Carboxylase
Andrimid is a peptide Antibiotic and acetyl-CoA carboxylase inhibitor. Andrimid is produced by symbiotic bacteria of the genus Enterobacter residing in the brown planthopper Nilaparvata lugens. Andrimid exhibits strong specific activity against Xanthomonas campestris pv. oryzae. Andrimid shows no or only weak activity against Gram-positive and Gram-negative bacteria, including most plant pathogenic bacteria. Andrimid can be used in studies related to bacterial infections and rice bacterial blight .

HY-123351

Kievitone	Flavonoids Leguminosae Isoflavanones Plants Phaseolus vulgaris Linn. Source Classification	Fungal
Kievitone, an isoflavanone, could be isolated from hypocotyls of Phaseolus vulgaris L. infected with Rhizoctonia solani* Kühn*. Kievitone has antifungal activity and antitumor activity .

HY-N12167

3-epi-Bufalin	Structural Classification Microorganisms Steroids Source Classification	Others
3-epi-Bufalin (compound 2a) is the microbial transformation product of bufadienolide .

HY-N10289

Cytosporone C	Infection Microorganisms Classification of Application Fields Phenols Polyphenols Disease Research Fields Source Classification	Fungal
Cytosporone C is an antifungal metabolite from the Melia azedarach-Associated Fungus Diaporthe eucalyptorum. Cytosporone C exhibits antifungal activities against Alternaria solani .

HY-W164451

N-(2-hydroxy-2-phenylethyl)acetamide	Infection Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Fungal
N-(2-hydroxy-2-phenylethyl)acetamide is isolated from the solid rice cultures of the endophytic fungus Diaporthe eucalyptorum KY-9. N-(2-hydroxy-2-phenylethyl)acetamide exhibits antifungal activities against Alternaria solani .

HY-N12475

Solavetivone	Structural Classification Terpenoids Sesquiterpenes Solanum virginianum Linnaeus Solanaceae Plants Source Classification	Fungal Cytochrome P450
Solavetivone is a Sesquiterpenoid phytoalexin and Antifungal agent. Solavetivone is isolated from stress-challenged potato plants. Solavetivone is hydroxylated by sesquiterpenoid phytoalexin hydroxylase (SPH/CYP76A2L). Solavetivone helps solanaceous plants defend against pathogens, damages plant cells after pathogen threat, and inhibits mycelial growth of Rhizoctonia solani. Solavetivone is applicable to studies related to Rhizoctonia solani infection .

HY-N14474

Fusarubin	Quinones Microorganisms Naphthalene Quinones Source Classification	Others
Fusarubin is a metabolite of Fusarium solani .

HY-N11528

Eugenitol 7-Noreugenitin	Natural Products Microorganisms Source Classification	Others
Eugenitol (Compound 3) is an antifungal metabolite isolated and purified from Diaporthe eucalyptorum. Eugenitol has inhibitory effect on four plant pathogenic fungi (Alternaria solani, Botrytis cinerea, Fusarium solani and Gibberella saubinettii) .

HY-N10288

Eucalyptacid A	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Fungal Endogenous Metabolite
Eucalyptacid A, an antifungal metabolite, exhibits antifungal activities against Alternaria solani, with MIC values from 6.25 to 50 μM .

HY-N10293

Monaschromone	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Phenols Polyphenols Disease Research Fields Source Classification	Fungal Endogenous Metabolite
Monaschromone, a polyketide metabolite, significantly inhibits the growth of B. cinerea, A. solani, M. oryzae, and G. saubinettii, with the MIC values ranging from 6.25 to 12.5 μM .

HY-125727

Globosuxanthone A	Infection Human Gut Microbiota Metabolites Monophenols Microorganisms Xanthones Classification of Application Fields Phenols Endogenous metabolite Disease Research Fields Cancer Source Classification	Fungal
Globosuxanthone A is a dihydroxanthenone with obvious antifungal activity towards Fusarium graminearum, Fusarium solani, and Botrytis cinerea with MIC values of 4, 8, and 16 μg/mL, respectively. Anticancer activity .

HY-N10292

Chaetosemin J	Infection Microorganisms Classification of Application Fields Phenols Polyphenols Disease Research Fields Source Classification	Fungal Endogenous Metabolite
Chaetosemin J, an antifungal metabolite, exhibits inhibitory activity against plant pathogenic fungi Botrytis cinerea, Alternaria solani, Magnaporthe oryzae, and Gibberella saubinettii, with MIC values ranging from 12.5-25 μM .

HY-N8499

Sporothriolide	Natural Products Microorganisms Source Classification	Fungal
Sporothriolide is a metabolite produced by Nodulisporium sp. A21. Sporothriolide has potently antifungal against R. solani and S. sclerotiorum, with EC₅₀ values of 11.6 μM and 10.7 μM, respectively. Sporothriolide inhibits conidium germination of Magnaporthe oryzae in vitro and in vivo .

HY-N14111

Cuevaene A	Microorganisms Antibiotics Other Antibiotics Source Classification	Bacterial Fungal
Cuevaene A can be isolated from the strain of gdmAI-disrupted Streptomyces sp. LZ35 and. Cuevaene A displays moderate activity against Gram-positive bacteria (e.g., Bacillus subtilis strain ATCC 11060) and modest activity against fungi (e.g., Fusarium verticillioides strain S68 and Rhizoctonia solani strain GXE4) .

HY-N14112

Cuevaene B	Microorganisms Antibiotics Other Antibiotics Source Classification	Bacterial Fungal
Cuevaene B can be isolated from the strain of gdmAI-disrupted Streptomyces sp. LZ35 and. Cuevaene B displays moderate activity against Gram-positive bacteria (e.g., Bacillus subtilis strain ATCC 11060) and modest activity against fungi (e.g., Fusarium verticillioides strain S68 and Rhizoctonia solani strain GXE4) .

HY-N12497

Moracin B	Phenols Polyphenols Morus alba L. Plants Moraceae Source Classification	Fungal
Moracin B is a phytoalexin with antifungal activity. Moracin B can be isolated from the cortex and phloem tissues of mulberry (Morus alba Linne) infected with Fusarium solani f. sp. mori. Moracin B can be used to study plant disease resistance mechanisms against microbial infections, particularly showing potential application value in the field of plant disease control .

HY-125511

Chaetoviridin A	Natural Products Microorganisms Source Classification	Fungal
Chaetoviridin A exhibits antifungal activity against several plants pathogen, inhibits growth of Verticillium dahliae through cell necrosis and mycelial deformation, and thus improves sensitivity of V. dahliae to stress, increases the emergence rate and plant height of cotton .

HY-W015343R

3-Methoxyphenylacetic acid (Standard) m-Methoxyphenylacetic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Endogenous Metabolite Reference Standards
3-Methoxyphenylacetic acid (Standard) is the analytical standard of 3-Methoxyphenylacetic acid. This product is intended for research and analytical applications. 3-Methoxyphenylacetic acid (m-Methoxyphenylacetic acid), a m-hydroxyphenylacetic acid (m-OHPAA) derivative, is a phytotoxin in Rhizoctonia solani. 3-Methoxyphenylacetic acid is used to develop a toxin-mediated bioassay for resistance to rhizoctonia root rot[1].

HY-N19881

Drimenal	Structural Classification Natural Products Bazzania trilobata (L.) Gray Lepidoziaceae Plants Source Classification	Fungal
Drimenal is a pimarane-type natural sesquiterpene with antifungal activity. Drimenal inhibits the growth of yeasts and dermatophytes. Drimenal can be used for the development of pesticide candidates and in research related to fungal infections .

HY-W743904

Quininone	Structural Classification Alkaloids Rubiaceae Cinchona calisaya Wedd. Quinoline Alkaloids Plants Source Classification	Drug Derivative Fungal
Quininone is a Quinine (HY-D0143) derivative that exhibits in vitro antifungal activity. Quininone can be used for antifungal research .

Cat. No.	Product Name	Chemical Structure

HY-N6625S

Chlorothalonil-13C2
Chlorothalonil- ¹³C₂ is the ¹³C-labeled Chlorothalonil. Chlorothalonil is a broad spectrum fungicide and is effective in protecting plants against fungal diseases caused mainly by Phytophthora infestans and Alternaria solani. Chlorothalonil is used for controlling of fungal foliar diseases of vegetables and crops .

HY-W150903S

N-Heptyl 4-hydroxybenzoate-d4
N-Heptyl 4-hydroxybenzoate-d₄ is the deuterium labeled N-Heptyl 4-hydroxybenzoate (HY-W150903) . N-Heptyl 4-hydroxybenzoate (p-Oxybenzoesaureheptylester) is an antimicrobial agent that inhibits S. aureus with MIC of 12.5 μg/mL. N-Heptyl 4-hydroxybenzoate also against plant pathogenic fungi, such as Alternaria brassicicola, F. solani, C. dematium and C. acutatum .

HY-W716702

Aldox-d6

Aldox-d₆ (Lexamine M-13-d₆; MAPD-d₆) is the deuterium labeled Myristamidopropyl dimethylamine (HY-W099582). Myristamidopropyl dimethylamine (MAPD) is an antimicrobial agent (including against bacteria and fungi) and an insecticide, exhibiting inhibitory activity against Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans, Fusarium solani, and Acanthamoeba polyphaga. Myristamidopropyl dimethylamine can be used in research on microbial-induced keratitis .

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