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Cat. No.: HY-174831

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SDH-IN-28

SDH-IN-28 is a succinate dehydrogenase inhibitor with an IC₅₀ value of 2.65 mg/L. SDH-IN-28 demonstrates broad-spectrum fungicidal efficacy, with EC₅₀ values of 0.21 (Valsa mali), 0.95 (Botrytis cinerea), 0.64 (Rhizoctonia solani), 1.33 (Fusarium graminearum), and 0.66 mg/L (Gaeumannomyces graminis). SDH-IN-28 effectively prevents V. mali infection in apples.

For research use only. We do not sell to patients.

Formula: C₂₀H₁₅Cl₂F₄N₅O₂S
Molecular Weight:536.33

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

SDH-IN-28 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

SDH-IN-28 (Compound 4d) (20 mg/L) shows good fungicidal activities with inhibition rate of V. mali (100%), S. sclerotiorum (94.3%), B. cinerea (86.1%), R. solani (100%), F. graminearum (88.0%), G. graminis (100%), and P. capsici (66.1%) at 20 mg/L^[1].

SDH-IN-28 (50 mg/L, 1-10 days) shows superior curative and protective efficiency in apples inoculated with V. mali for 24 h^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 536.33
Formula C₂₀H₁₅Cl₂F₄N₅O₂S
SMILES

O=C(NC1=C(SCC(NNC2=CC=C(F)C=C2)=O)C(C(F)(F)F)=NN1C)C3=CC(Cl)=CC(Cl)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Li Y, et al. Discovery of novel 4-sulfur-substituted pyrazol-5-yl-benzamide derivatives containing amide/hydrazide/ester moieties as potential succinate dehydrogenase inhibitors. Pest Manag Sci. 2025 Jun 2.1. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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