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Cat. No.: HY-W281071

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Antifungal agent 150

Antifungal agent 150 is an antifungal agent with activity against phytopathogenic fungi and in planta lesion suppression. Antifungal agent 150 inhibits ergosterol biosynthesis via targeted enzyme interaction. Antifungal agent 150 can be used for the research of plant diseases caused by Rhizoctonia solani, including banded leaf and sheath blight of maize.

For research use only. We do not sell to patients.

CAS No.: 67365-93-9
Formula: C₉H₆Cl₂N₂OS₂
Molecular Weight:293.19

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Antifungal agent 150 Chemical Structure

CAS No.: 67365-93-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

Antifungal agent 150 (1.5625-25 μg/mL) inhibits Rhizoctonia solani ergosterol biosynthesis with an EC₅₀ of 3.604 μg/mL, achieving 81.07% inhibition at 25 μg/mL^[1].
Antifungal agent 150 (3-12 μg/mL; spray; single dose) dose-dependently inhibits R. solani lesion growth on maize leaves, with the 12 μg/mL dose showing the strongest activity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 67365-93-9
Molecular Weight 293.19
Formula C₉H₆Cl₂N₂OS₂
SMILES

C1=CC(=C(C=C1Cl)Cl)OCC2=NN=C(S)S2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Singh AK, et al. Virtual Screening-Based Synthesis of 1,3,4-Thiadiazole Derivatives and Their Evaluation for Fungicidal Activity, Ergosterol Inhibition, and Aquatic Toxicity. J Agric Food Chem. 2026;74(1):549-559. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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