1. Anti-infection
  2. Fungal
  3. SDH-IN-4

SDH-IN-4 (compound B6) is a selective inhibitor against succinate dehydrogenase (SDH) with an IC50 value of 0.28 μg/mL. SDH-IN-4 has highly efficient and broad-spectrum antifungal activity, against R. solani with an EC50 value of 0.23 μg/mL.

For research use only. We do not sell to patients.

SDH-IN-4 Chemical Structure

SDH-IN-4 Chemical Structure

CAS No. : 2982993-88-2

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Description

SDH-IN-4 (compound B6) is a selective inhibitor against succinate dehydrogenase (SDH) with an IC50 value of 0.28 μg/mL. SDH-IN-4 has highly efficient and broad-spectrum antifungal activity, against R. solani with an EC50 value of 0.23 μg/mL[1].

In Vitro

SDH-IN-4 (10 μg/mL, 3-5 days) inhibits mycelium growth of fungal R. solani, F. graminearum, B. cinerea and A. solani[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

SDH-IN-4 (100 μg/mL, 5 days) inhibits R. solani in detached rice leaves was 87.48%[1].
SDH-IN-4 (20 μg/mL, 0.5-3 h) inhibits the growth and development of mycelia of R. solani and causes serious damage to the mycelial cell membrane[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

389.18

Formula

C11H9Cl2F3N4O2S

CAS No.
SMILES

O=S(C1=C(C)NN=C1C(F)(F)F)(NNC2=CC=C(Cl)C=C2Cl)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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References
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SDH-IN-4 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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SDH-IN-4
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HY-149323
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