1. Metabolic Enzyme/Protease Anti-infection
  2. Succinate Dehydrogenase Fungal
  3. SDH-IN-37

SDH-IN-37 (Compound A37) is a potent SDH inhibitor, with an IC50 value of 0.0263 μM. SDH-IN-37 is also an antifungal agent. SDH-IN-37 demonstrates antifungal activities against Rhizoctonia solani, S. sclerotiorum and F. graminearum, with EC50 values of 0.0144, 0.882 and 1.99 μg/mL, respectively.

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SDH-IN-37

SDH-IN-37 Chemical Structure

CAS No. : 3085095-58-2

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Description

SDH-IN-37 (Compound A37) is a potent SDH inhibitor, with an IC50 value of 0.0263 μM. SDH-IN-37 is also an antifungal agent. SDH-IN-37 demonstrates antifungal activities against Rhizoctonia solani, S. sclerotiorum and F. graminearum, with EC50 values of 0.0144, 0.882 and 1.99 μg/mL, respectively[1].

IC50 & Target

IC50: 0.0263 μM (SDH)[1]

Molecular Weight

419.35

Formula

C21H14F5N3O

CAS No.
SMILES

CN(C=C1C(C(CC2=CC(C3=CC(F)=C(C(F)=C3)F)=CC=C2)C#N)=O)N=C1C(F)F

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
SDH-IN-37
Cat. No.:
HY-178799
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