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Cat. No.: HY-181492

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Antifungal agent 155 hydrochloride

Antifungal agent 155 hydrochloride is an antifungal agent. Antifungal agent 155 hydrochloride induces bent, twisted, abnormally swollen hyphae, compromises fungal hyphal plasma membrane integrity, and triggers fungal cell death. Antifungal agent 155 hydrochloride can be used for the research of fusarium keratitis.

For research use only. We do not sell to patients.

Formula: C₂₃H₂₆ClF₃N₄O
Molecular Weight:466.93

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Antifungal agent 155 hydrochloride Chemical Structure

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Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

Antifungal agent 155 hydrochloride (Compound B8) (0.125-256 μg/mL; 48-50 h) exhibits potent antifungal activity against clinical isolates of Fusarium solani, with MIC values ranging from 4 to 8 μg/mL^[1].
Antifungal agent 155 hydrochloride (50 μg/mL) induces significant morphological damage to Fusarium solani strain 211,882 hyphae, including bent, twisted, abnormally swollen^[1].
Antifungal agent 155 hydrochloride (5-100 μg/mL; 24 h) dose-dependently compromises the plasma membrane integrity of Fusarium solani and induces fungal cell death^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Immunofluorescence^[1]

Cell Line:

Fusarium solani
Concentration:

5, 10, 50 and 100 μg/mL
Incubation Time:

24 h
Result:

Increased red fluorescence and reduced green fluorescence.

Chemical Information

Molecular Weight 466.93
Formula C₂₃H₂₆ClF₃N₄O
SMILES

CCCCC1=CC=C(C2=CC(C(F)(F)F)=NN2C3=CC=C(C(NCCN)=O)C=C3)C=C1.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ma Y, et al. Antifungal activity of AR-12 and its derivatives against clinically relevant fusarium solani isolates in keratitis. Bioorg Chem. 2026;170:109516. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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