CYP51-IN-27
CYP51-IN-27 is a sterol 14α-demethylase CYP51 inhibitor with an IC50 of 0.3434 μg/mL. CYP51-IN-27 exhibits antifungal activity and inhibits the production of fungal ergosterol. CYP51-IN-27 can be used for the research of infection, such as rice sheath blight.
For research use only. We do not sell to patients.
- Formula: C22H12F6N4
- Molecular Weight:446.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CYP51 0.3434 μg/mL (IC50) |
CYP51-IN-27 (Compound 4r) demonstrates excellent efficacy against R. solani, with EC50 values of 0.33 μg/mL[1].
CYP51-IN-27 (20 μg/mL, 4 days) causes mycelium became desiccated, twisted, and irregular, with a rough, wrinkled, and collapsed surface, accompanied by the presence of some fragments in R. solani[1].
CYP51-IN-27 (200 μg/mL, 7-28 days) exhibits good protective and curative activities against R. solani on rice plants[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 446.35
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Formula C22H12F6N4
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SMILES
N#CNC(N=C/12)=NC(C3=CC(F)=C(F)C(F)=C3)=C2CCCC1=C/C4=CC(F)=C(F)C(F)=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CYP51-IN-27 Related Classifications
HY-178162 Related Classifications
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