DHFR-IN-13
DHFR-IN-13 (Compd Hit8) is an active R. solani DHFR inhibitor with an IC50 value of 10.2 μM. DHFR-IN-13 has selectivity of inhibition against human DHFR with an IC50 value of 227.7 μM. DHFR-IN-13 also is a fungicide. DHFR-IN-13 has high antifungal activity against R. solani with EC50 value of 38.2 mg/L.
For research use only. We do not sell to patients.
- Formula: C24H24ClFN2O3S
- Molecular Weight:474.98
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 10.2 μM (R. solani DHFR); 227.7 μM (human DHFR); EC50: 38.2 mg/L (R. solani)[1]
Chemical Information
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Molecular Weight 474.98
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Formula C24H24ClFN2O3S
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SMILES
ClC1=C(F)C=C(N2[C@]3(C(N4C5=C3C=C(OCC)C=C5[C@@H](C)CC4(C)C)=O)SCC2=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)