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Cat. No.: HY-162648

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Succinate dehydrogenase-IN-1

Succinate dehydrogenase-IN-1 (Compound 34) is an inhibitor for succinate dehydrogenase (SDH) with an IC₅₀ of 0.94 μM and a K_D of 22.4 μM. Succinate dehydrogenase-IN-1 exhibits antifungal activity against Rhizoctonia solani, Sclerotinia sclerotiorum, Monilinia fructicola, and Botrytis cinerea, with EC₅₀ of 0.04 μM, 1.13 μM, 1.61 μM and 1.21 μM, respectively.

For research use only. We do not sell to patients.

CAS No.: 2969128-94-5
Formula: C₂₀H₁₃F₆N₃O
Molecular Weight:425.33

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Succinate dehydrogenase-IN-1 Chemical Structure

CAS No.: 2969128-94-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 2969128-94-5
Molecular Weight 425.33
Formula C₂₀H₁₃F₆N₃O
SMILES

O=C(C1=CN(C)N=C1C(F)F)NC2=CC=CC=C2/C(F)=C/C3=CC(F)=C(F)C(F)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chen Y, et al., Design, Synthesis, and Antifungal Activities of Novel Potent Fluoroalkenyl Succinate Dehydrogenase Inhibitors. J Agric Food Chem. 2024 Jul 3;72(26):14535-14546. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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