1. NF-κB
    Anti-infection
    Apoptosis
    Epigenetics
    Cell Cycle/DNA Damage
  2. Keap1-Nrf2
    Arenavirus
    Caspase
    PARP
  3. 5,7-Dihydroxychromone

5,7-Dihydroxychromone 

Cat. No.: HY-N1970
Handling Instructions

5,7-Dihydroxychromone, the extract of Cudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis. 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells.

For research use only. We do not sell to patients.

5,7-Dihydroxychromone Chemical Structure

5,7-Dihydroxychromone Chemical Structure

CAS No. : 31721-94-5

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Description

5,7-Dihydroxychromone, the extract of Cudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis. 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells[1].

IC50 & Target

Nrf2

 

Caspase-3

 

Caspase-9

 

PARP

 

Molecular Weight

178.14

Formula

C₉H₆O₄

CAS No.

31721-94-5

SMILES

O=C1C=COC2=CC(O)=CC(O)=C12

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5,7-Dihydroxychromone
Cat. No.:
HY-N1970
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