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Results for "

insecticidal+activity

" in MedChemExpress (MCE) Product Catalog:

108

Inhibitors & Agonists

3

Peptides

40

Natural
Products

6

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-126741
    Azadirachtin
    2 Publications Verification

    		 Environmental Pollutants Parasite Caspase NF-κB Apoptosis Bcl-2 Family Infection Inflammation/Immunology Cancer
    Azadirachtin is an oral active triterpenoid compound with anticancer, antimalarial, anti-inflammatory, and insecticidal activities. Azadirachtin induces cell apoptosis through the mitochondrial pathway (by inhibiting Bcl-2/Bax ratio or activating Apaf-1 and caspase-3) or through death receptors (by inhibiting TNFR activation). Additionally, Azadirachtin exerts its anti-inflammatory effects by inhibiting NF-кB signaling pathway activation, and it exhibits insecticidal activity by inducing apoptosis in insect cells .
    Azadirachtin
  • HY-114936
    Piericidin A
    5 Publications Verification

    AR-054

    		 Bacterial ADC Payload Antibiotic Mitochondrial Metabolism Infection Neurological Disease Cancer
    Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity .
    Piericidin A
  • HY-17530
    Aldicarb sulfone

    		Environmental Pollutants Drug Metabolite Parasite Cholinesterase (ChE) Infection
    Aldicarb sulfone is one of the metabolites of the carbamate pesticide Aldicarb and has insecticidal activity. Aldicarb sulfone is also an inhibitor of cholinesterase .
    Aldicarb sulfone
  • HY-117386
    Methoxyfenozide
    1 Publications Verification

    		 Environmental Pollutants Insecticide Infection
    Methoxyfenozide is an orally active insecticide belonging to the diacylhydrazine and non-steroidal ecdysone agonist classes, which can interfere with the growth and development of insects. Methoxyfenozide has ovicidal and insecticidal activities against phytophagous pests .
    Methoxyfenozide
  • HY-107577
    Gedunin

    		HSP Infection Inflammation/Immunology Cancer
    Gedunin is a limonoid with anti-cancer, anti-viral, anti-inflammatory and insecticidal activities. Gedunin acts as a potent Hsp90 inhibitor and induces the degradation of Hsp90-dependent client proteins. Geduni may obstructs the entry of SARS-CoV-2 virus into human host cells and can be used for COVID-19 research .
    Gedunin
  • HY-W006957
    N6-(2-Hydroxyethyl)adenosine
    1 Publications Verification

    		 Nucleoside Antimetabolite/Analog Insecticide NF-κB TGF-beta/Smad Reactive Oxygen Species (ROS) Apoptosis Autophagy Mitochondrial Metabolism SOD Cardiovascular Disease Inflammation/Immunology Cancer
    N6-(2-Hydroxyethyl)adenosine is a purine nucleoside analog. N6-(2-Hydroxyethyl)adenosine inhibits NF-κB/Smad signaling pathway, exhibits anti-hyperglycemia, antioxidant, antitumor and anti-inflammatory and insecticidal activities. N6-(2-Hydroxyethyl)adenosine is orally active .
    N6-(2-Hydroxyethyl)adenosine
  • HY-111664
    (R)-(+)-Citronellal

    (+)-Citronellal

    		 Bacterial Fungal Insecticide Taste Receptor Opioid Receptor Infection Neurological Disease Inflammation/Immunology
    (R)-(+)-Citronellal ((+)-Citronellal) is a monoterpenoid compound and is one of the main components of essential oils from plants such as lemon grass. (R)-(+)-Citronellal has antibacterial, antifungal, and insecticidal activities. (R)-(+)-Citronellal alleviates the bitterness of caffeine by antagonizing the bitter taste receptors Tas2r43 (IC50 = 84 μM) and Tas2R46. (R)-(+)-Citronellal generates analgesic activity by activating the opioid receptor (broad-spectrum opioid receptor) pathway, and its effect is particularly significant for inflammatory pain .
    (R)-(+)-Citronellal
  • HY-164322
    Cyproflanilide

    		Insecticide Others
    Cyproflanilide is a meta-diamide insecticide. Cyproflanilide exhibits potent insecticidal activity against third Chilo suppressalis and Spodoptera frugiperda larvae. Cyproflanilide can be used for the research of insect pests .
    Cyproflanilide
  • HY-B0834
    (±)-Indoxacarb

    (RS)-Indoxacarb; DPX-JW062

    		 Environmental Pollutants Sodium Channel Neurological Disease
    Indoxacarb ((±)-Indoxacarb; DPX-JW062) is a broad-spectrum oxadiazine insecticide with high insecticidal activity and low mammalian toxicity. Indoxacarb blocks insect sodium channels in nerve preparations and isolated neurons .
    (±)-Indoxacarb
  • HY-B1858
    Isoprothiolane
    2 Publications Verification

    		 Environmental Pollutants Parasite Fungal Interleukin Related Infection Metabolic Disease Inflammation/Immunology
    Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver .
    Isoprothiolane
  • HY-N4202
    Dihydrorotenone

    		Environmental Pollutants Insecticide Apoptosis p38 MAPK Neurological Disease Inflammation/Immunology Cancer
    Dihydrorotenone is an insecticide and irreversible inhibitor of mitochondrial complex I. Dihydrorotenone may induce Parkinson's disease. Dihydrorotenone induces apoptosis in human plasma cells by triggering endoplasmic reticulum stress and activating the p38 signaling pathway. The oral LD50 of dihydrorotenone in rats is approximately 2.5 g/kg. Dihydrorotenone exhibits insecticide activity and cytotoxicity to plasma cells. Dihydrorotenone can be used to establish animal models of Parkinson's disease, safety assessment of natural pesticides, and potential cancer chemoprevention studies .
    Dihydrorotenone
  • HY-136330
    Oxazosulfyl

    		Insecticide Parasite Sodium Channel Infection
    Oxazosulfyl is a sulfyl insecticide with potent and cross-spectrum insecticidal activity. Oxazosulfyl inhibits sodium currents by binding to and stabilizing the slow-inactivated state of voltage-gated sodium channels, leading to insect paralysis. Oxazosulfyl's ability to block sodium channels is correlated with its insecticidal activity .
    Oxazosulfyl
  • HY-133721
    Chamaechromone

    		HBV Infection Inflammation/Immunology
    Chamaechromone is a biflavonoid ingredient isolated from the roots of Stellera chamaejasme L. (Thymelaeaceae). Chamaechromone possesses anti-hepatitis B virus (HBV) effects against the surface antigen of HBV (HBsAg) secretion and has insecticidal activities .
    Chamaechromone
  • HY-B2015
    Carbosulfan

    		Environmental Pollutants Insecticide Parasite Cholinesterase (ChE) Infection
    Carbosulfan is an orally active AChE inhibitor that hydrolyzes to Carbofuran in organisms to exert insecticidal effects. Carbosulfan exhibits broad-spectrum insecticidal activity, and it also induces severe oxidative stress by enhancing lipid peroxidation and impairing the antioxidant defense system. Carbosulfan causes reproductive toxicity in male rats and developmental disorders in their offspring. Carbosulfan shows persistence in paddy field environments and potential hazards to non-target organisms, and it is commonly used in studies related to reproductive toxicity and environmental risk assessment .
    Carbosulfan
  • HY-N9496
    Piperitone

    		Insecticide Infection
    Piperitone is as a powerful repellent and antiappetent agent. Piperitone is very toxic to Cymbopogon schoenanthus (C. schoenanthus) adults, newly laid eggs and to neonate larvae. Insecticidal activity .
    Piperitone
  • HY-N16433
    Nodulisporic acid A

    		Parasite Insecticide Infection
    Nodulisporic acid A (Compound 1a) is an insecticidal agent. Nodulisporic acid A can isolated from fermentations of Nodulisporium sp. Nodulisporic acid A has a potent insecticidal activity against the larvae of the blowfly and mosquito with LC50s of 0.5 and 0.3 ppm against A. aegypti and L. seracata, respectively. Nodulisporic acid A can be used for the development of insecticide .
    Nodulisporic acid A
  • HY-130423
    Milbemycin A3

    		Insecticide Infection
    Milbemycin A3 is a 16-membered macrocyclic lactone compound found in the soil bacterium Saccharopolyspora hygroscopicus subsp. aureolacrimosus. Milbemycin A3 enhances the opening of glutamate- and GABA-gated chloride channels and exhibits insecticidal activity. Milbemycin A3 can be used in insect resistance-related research .
    Milbemycin A3
  • HY-N1418
    (S)-(-)-Tetrahydroberberine

    (-)-Canadine; (S)-(-)-Canadine

    		 Others Inflammation/Immunology
    (S)-(-)-Tetrahydroberberine is an alkaloid and intermediate in the biosynthesis of berberine with insecticidal activity .
    (S)-(-)-Tetrahydroberberine
  • HY-N12093
    Cevadine

    		Sodium Channel Parasite Infection
    Cevadine is a voltage-sensitive sodium channel agonist. Cevadine has insecticidal activity .
    Cevadine
  • HY-N4250
    Periplocoside N

    		Others Infection
    Periplocoside N, a pregnane glycoside isolated from root powder of Periploca sepium, possesses insecticidal activities against the red imported fire ant .
    Periplocoside N
  • HY-W698871
    (±) Anabasine-d4

    		Isotope-Labeled Compounds Endogenous Metabolite Others
    (±) Anabasine-d4 is the deuterium labeled (±) Anabasine (HY-W052144). (±) Anabasine is the racemate of Anabasine (HY-B1532). Anabasine is an agonist of α7nAChR and exhibits anti-inflammatory and insecticidal activities .
    (±) Anabasine-d4
  • HY-N9496R
    Piperitone (Standard)

    		Insecticide Reference Standards Infection
    Piperitone (Standard) is the analytical standard of Piperitone. This product is intended for research and analytical applications. Piperitone is as a powerful repellent and antiappetent agent. Piperitone is very toxic to Cymbopogon schoenanthus (C. schoenanthus) adults, newly laid eggs and to neonate larvae. Insecticidal activity .
    Piperitone (Standard)
  • HY-W024365
    3-tert-Butyl-4-methoxyphenol

    		PROTAC Linkers Cancer
    3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system .
    3-tert-Butyl-4-methoxyphenol
  • HY-162935
    V-ATPase-IN-1

    		Proton Pump Others
    V-ATPase-IN-1 (Compound 3b-03) is a Vacuolar-type H +-ATPases (V-ATPase) inhibitor (IC50 = 194.80 μM) that can effectively target the V-ATPase subunit A (Kd = 0.803 μM). V-ATPase-IN-1 exhibits insecticidal activity against M. separata (LC50 = 2.64 mM) and contributes to research in the development of chemical insecticides .
    V-ATPase-IN-1
  • HY-W011035
    Dodecamethylpentasiloxane

    		Parasite Infection
    Dodecamethylpentasiloxane is a component of siloxanes and can be used as silicone oil. Dodecamethylpentasiloxane exhibits insecticidal activity against bed bug .
    Dodecamethylpentasiloxane
  • HY-117386S
    Methoxyfenozide-d9

    		Isotope-Labeled Compounds Insecticide Infection
    Methoxyfenozide-d9 is the deuterium labeled Methoxyfenozide (HY-117386). Methoxyfenozide is an orally active insecticide belonging to the diacylhydrazine and non-steroidal ecdysone agonist classes, which can interfere with the growth and development of insects. Methoxyfenozide has ovicidal and insecticidal activities against phytophagous pests .
    Methoxyfenozide-d9
  • HY-178040
    Insecticidal agent 26

    		Acetyl-CoA Carboxylase Pyruvate Carboxylase (PC) Parasite Insecticide Infection
    Insecticidal agent 26 (Compound A11), a spiro insecticidal agent, is a dual-functional inhibitor of pest Acetyl-CoA carboxylase (ACC) and Pyruvate carboxylase (PC). Insecticidal agent 26 has potent insecticidal activity against Sogatella furcifera with a LC50 of 11.0  μg/mL, with significant biosafety to bees. Insecticidal agent 26 can be used for management of white-backed planthoppers (WBPs) .
    Insecticidal agent 26
  • HY-W052144
    (±) Anabasine
    2 Publications Verification

    		 Endogenous Metabolite Others
    (±) Anabasine is the racemate of Anabasine (HY-B1532). Anabasine is an agonist of α7nAChR and exhibits anti-inflammatory and insecticidal activities .
    (±) Anabasine
  • HY-N3068
    Picrasin B

    Nigakilactone I; Simalikalactone B

    		 Others Others
    Picrasin B (Nigakilactone I) can be isolated from the bark of Picrasma quassioides. Picrasin B shows antifeedant and insecticidal activity against Diamondback Moth .
    Picrasin B
  • HY-I0144
    Thiazolidine

    		Drug Intermediate Others
    Thiazolidine is a five-membered heterocyclic compound containing sulfur and nitrogen heteroatoms. Thiazolidine is an important intermediate in organic synthesis. Thiazolidine derivatives possess diverse bioactivities, such as anti-tumor, antibacterial and insecticidal activities, and the capacity to reduce blood glucose levels .
    Thiazolidine
  • HY-W007980
    Antifungal agent 98

    		Fungal Infection
    Antifungal agent 98 (compound 2) is an antifungal agent. Antifungal agent 98 (100 μg/mL) shows insecticidal activity against Bipolaris sorokinianum, Fusarium oxysporium f. sp.vasinfectum, Pyricularia oryzae, Alternaria Brassicae and Alternaria alternata with a death rate of 41.5%, 40.0%, 23.4, 36.8%, and 35.0% .
    Antifungal agent 98
  • HY-N8472
    Chrodrimanin B

    		GABA Receptor Infection
    Chrodrimanin B, a metabolite of a fungal, is a potent, non-open-channel-blocking antagonist on?B.?mori GABAR RDL with an IC50?of 1.13 nM. Chrodrimanin B attenuates the peak current amplitude of the GABA response of RDL with an IC50?of 1.66 nM.?Chrodrimanin B, a meroterpenoid, shows insecticidal activity .
    Chrodrimanin B
  • HY-158721
    Penicinoline

    Marinamide

    		 Endogenous Metabolite Parasite Infection Cancer
    Penicinoline (Marinamide) (Compound 1), a pyrrolyl 4-quinolinone alkaloid, is a microbial secondary metabolite. Penicinoline can be isolated from endophytic fungus Penicillium sp. Penicinoline has antimalarial activity against Chloroquine (HY-17589A) sensitive strain (pf3d7) and against Chloroquine resistant strain (pfDd2) of plasmodium falciparum. Penicinoline also has strong insecticidal activity against Aphis gossypii and selective anticancer effect with significant cytotoxicity for 95-D and HepG2 cells .
    Penicinoline
  • HY-118428
    Fluenetil

    M2060; TH 367-1

    		 Insecticide Others
    Fluenetil (M2060) is a compound with insecticidal activity.
    Fluenetil
  • HY-N3156
    Odoratone

    Dehydroodoratol

    		 Parasite Others
    Odoratone (Dehydroodoratol) has insecticidal activity (LC50: 154 ppm) .
    Odoratone
  • HY-142916
    Insecticidal agent 1

    		Insecticide Others
    Insecticidal agent 1 displays more potent insecticidal activity than obacunone and toosendanin.
    Insecticidal agent 1
  • HY-P10390
    Insecticidal agent 11

    		Parasite Infection
    Insecticidal agent 11 (compound Q6) is a potent insect growth regulator (IGR)-based insecticide. Insecticidal agent 11 shows high insecticidal activity against Diploptera punctata by inhibiting juvenile hormone (JH) biosynthesis. Insecticidal agent 11 also exhibits insecticidal activity against Plutella xylostella .
    Insecticidal agent 11
  • HY-134625
    Kalecide

    		Insecticide Others
    Kalecide is an isobutylamide found in Piper guineense. Kalecide shows insecticidal activity and can be used for insecticide .
    Kalecide
  • HY-N14917
    Destruxins C

    		Insecticide Infection
    Destruxins C is found in the strain of Hyphomycetes and Metarrhiziurn anosopliae. Destruxins C has insecticidal activity .
    Destruxins C
  • HY-N3507
    Euojaponine D

    		Others Others
    Euojaponine D is a sesquiterpene alkaloids from Euonymus japonica (Celastraceae). Celastraceae has potent insecticidal activity .
    Euojaponine D
  • HY-N1520
    Rediocide A

    		Others Infection
    Rediocide A is a highly modified daphnane with potent insecticidal activity. Rediocide A can be isolated from Trigonostemon reidioides .
    Rediocide A
  • HY-N12548
    Thamnosmonin

    		Others Others
    Thamnosmonin is a coumarin that can be isolated from Sida acuta and Sida rhombifolia. Thamnosmonin has insecticidal activity .
    Thamnosmonin
  • HY-116631
    Sarisan

    Asaricin

    		 Fungal Insecticide Infection
    Sarisan (Asaricin) is a phenolic derivative with antifungal and insecticidal activity. Sarisan can be found in the stem bark of Ocotea opifera Mart. .
    Sarisan
  • HY-122401
    Daigremontianin

    		Insecticide Infection
    Daigremontianin is an insecticidal bufadienolide that can be isolated from K. daigremontiana x tubiflora. Daigremontianin shows insecticidal activity for silkworm .
    Daigremontianin
  • HY-156256
    Insecticidal agent 4

    		Bacterial Infection
    Insecticidal agent 4 (compound IA-8) is an aryl isoxazoline derivative with insecticidal activity against M. separate .
    Insecticidal agent 4
  • HY-114720
    Laureatin

    		Insecticide Others
    Laureatin is an active product that can be isolated from the marine algae Laurencia nipponica. Laureatin exhibits potent insecticidal activity against mosquitos .
    Laureatin
  • HY-P1991
    Isariin D

    		Parasite Infection
    Isariin D is a cyclodepsipeptide isolated from the fungus Isaria felina, which exhibits significant insecticidal activity against Galleria mellonella larvae .
    Isariin D
  • HY-W052144R
    (±) Anabasine (Standard)

    		Reference Standards Endogenous Metabolite Others
    (±) Anabasine is the racemate of Anabasine (HY-B1532). Anabasine is an agonist of α7nAChR and exhibits anti-inflammatory and insecticidal activities .
    (±) Anabasine (Standard)
  • HY-N8668
    Eudesmane K

    		Others Others
    Eudesmane K exhibits insecticidal activity against main pests to crops Lipaphis erysimi, Sitobion avenae, Rhopalosiphum padi, and Aphis craccivora .
    Eudesmane K
  • HY-N8355
    Beauveriolide I

    		Endogenous Metabolite Infection
    Beauveriolide I is the metabolite of Entomopathogenic Fungi Beauveria sp.. Beauveriolide I (1) exhibits moderate insecticidal activities against Spodoptera litura and Callosobruchus chinensis .
    Beauveriolide I

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