(±) Anabasine-d4
Based on 1 Customer Validation
(±) Anabasine-d4 is the d4-labeled (±) Anabasine (HY-W052144). (±) Anabasine is the racemic form of Anabasine (HY-B1532). (±) Anabasine stimulates the release of [3H]-Dopamine from mouse striatal synaptosomes. (±) Anabasine inhibits the high-affinity binding of [3H]-S-(-)-Nicotine to the striatal membrane. Anabasine is an agonist of α7nAChR and possesses anti-inflammatory and insecticidal activities.
For research use only. We do not sell to patients.
- Purity: 99.30%
- CAS No.: 1020719-08-7
- Formula: C10H10D4N2
- Molecular Weight:166.26
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Dopamine Receptor Isoforms
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Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1020719-08-7
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Unlabeled Cas 13078-04-1
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Appearance Oil
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Molecular Weight 166.26
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Formula C10H10D4N2
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Color Off-white to light yellow
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SMILES
[2H]C1=C(C([2H])=NC([2H])=C1C2NCCCC2)[2H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 130 mg/mL (781.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Handling Instructions (2659 KB)
References
[1]. Zhang YX, et al. Nicotine improves DSS-induced colitis by inhibiting NLRP3 and altering gut microbiota. J Asian Nat Prod Res. 2024 May;26(5):616-635. [Content Brief]
[2]. Ayers JT, et al. A general procedure for the enantioselective synthesis of the minor tobacco alkaloids nornicotine, anabasine, and anatabine. AAPS J. 2005 Oct 31;7(3):E752-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.0147 mL | 30.0734 mL | 60.1468 mL | 150.3669 mL |
| 5 mM | 1.2029 mL | 6.0147 mL | 12.0294 mL | 30.0734 mL | |
| 10 mM | 0.6015 mL | 3.0073 mL | 6.0147 mL | 15.0367 mL | |
| 15 mM | 0.4010 mL | 2.0049 mL | 4.0098 mL | 10.0245 mL | |
| 20 mM | 0.3007 mL | 1.5037 mL | 3.0073 mL | 7.5183 mL | |
| 25 mM | 0.2406 mL | 1.2029 mL | 2.4059 mL | 6.0147 mL | |
| 30 mM | 0.2005 mL | 1.0024 mL | 2.0049 mL | 5.0122 mL | |
| 40 mM | 0.1504 mL | 0.7518 mL | 1.5037 mL | 3.7592 mL | |
| 50 mM | 0.1203 mL | 0.6015 mL | 1.2029 mL | 3.0073 mL | |
| 60 mM | 0.1002 mL | 0.5012 mL | 1.0024 mL | 2.5061 mL | |
| 80 mM | 0.0752 mL | 0.3759 mL | 0.7518 mL | 1.8796 mL | |
| 100 mM | 0.0601 mL | 0.3007 mL | 0.6015 mL | 1.5037 mL |
(±) Anabasine-d4 Related Classifications
HY-W698871 Related Classifications
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