13078-04-1
13078-04-1
Chemical Structure
(±) Anabasine
- CAS. Nr.: 13078-04-1
- Formula:C10H14N2
- Molecular Weight:162.24
IUPAC Name: 3-(piperidin-2-yl)pyridine
InChIKey: MTXSIJUGVMTTMU-UHFFFAOYSA-N
SMILES: C1(C2NCCCC2)=CC=CN=C1
Biological Activity: (±) Anabasine is the racemic form of Anabasine (HY-B1532). (±) Anabasine stimulates the release of [3H]-Dopamine from mouse striatal synaptosomes. (±) Anabasine inhibits the high-affinity binding of [3H]-S-(-)-Nicotine to the striatal membrane. Anabasine is an agonist of α7nAChR and possesses anti-inflammatory and insecticidal activities[1][2].
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(±) Anabasine | 98.55% | (±) Anabasine is the racemic form of Anabasine (HY-B1532). (±) Anabasine stimulates the release of [3H]-Dopamine from mouse striatal synaptosomes. (±) Anabasine inhibits the high-affinity binding of [3H]-S-(-)-Nicotine to the striatal membrane. Anabasine is an agonist of α7nAChR and possesses anti-inflammatory and insecticidal activities. | ||||||||||||||||||||
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(±) Anabasine (Standard) | 98.15% | (±) Anabasine (Standard) is the analytical standard of (±) Anabasine (HY-W052144). This product is intended for research and analytical applications. (±) Anabasine is the racemic form of Anabasine (HY-B1532). (±) Anabasine stimulates the release of [3H]-Dopamine from mouse striatal synaptosomes. (±) Anabasine inhibits the high-affinity binding of [3H]-S-(-)-Nicotine to the striatal membrane. Anabasine is an agonist of α7nAChR and possesses anti-inflammatory and insecticidal activities. | ||||||||||||||||||||
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(±) Anabasine-d4 | 99.30% | (±) Anabasine-d4 is the d4-labeled (±) Anabasine (HY-W052144). (±) Anabasine is the racemic form of Anabasine (HY-B1532). (±) Anabasine stimulates the release of [3H]-Dopamine from mouse striatal synaptosomes. (±) Anabasine inhibits the high-affinity binding of [3H]-S-(-)-Nicotine to the striatal membrane. Anabasine is an agonist of α7nAChR and possesses anti-inflammatory and insecticidal activities. | ||||||||||||||||||||
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References
- [1]. Zhang YX, et al. Nicotine improves DSS-induced colitis by inhibiting NLRP3 and altering gut microbiota. J Asian Nat Prod Res. 2024 May;26(5):616-635. [Content Brief]
- [2]. Ayers JT, et al. A general procedure for the enantioselective synthesis of the minor tobacco alkaloids nornicotine, anabasine, and anatabine. AAPS J. 2005 Oct 31;7(3):E752-8. [Content Brief]
