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Cat. No.: HY-W209279

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(±) Anabasine hydrochloride

(±) Anabasine hydrochloride is the racemic form of Anabasine (HY-B1532). (±) Anabasine hydrochloride stimulates the release of [³H]-Dopamine from mouse striatal synaptosomes. (±) Anabasine hydrochloride inhibits the high-affinity binding of [³H]-S-(-)-Nicotine to the striatal membrane. Anabasine hydrochloride is an agonist of α7nAChR and possesses anti-inflammatory and insecticidal activities.

For research use only. We do not sell to patients.

CAS No.: 352220-15-6
Formula: C₁₀H₁₅ClN₂
Molecular Weight:198.69

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

(±) Anabasine hydrochloride Chemical Structure

CAS No.: 352220-15-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

All Dopamine Receptor Isoforms :

In Vitro

(±) Anabasine hydrochloride stimulates the release of [³H]-Dopamine release from mouse striatal synaptosomes ^[2].
(±) Anabasine hydrochloride inhibits the high-affinity binding of [³H]-S-(-)-Nicotine to rat and mouse striatal membranes^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 352220-15-6
Molecular Weight 198.69
Formula C₁₀H₁₅ClN₂
SMILES

C1(C2NCCCC2)=CN=CC=C1.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang YX, et al. Nicotine improves DSS-induced colitis by inhibiting NLRP3 and altering gut microbiota. J Asian Nat Prod Res. 2024 May;26(5):616-635. [Content Brief]

[2]. Ayers JT, et al. A general procedure for the enantioselective synthesis of the minor tobacco alkaloids nornicotine, anabasine, and anatabine. AAPS J. 2005 Oct 31;7(3):E752-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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