Cyetpyrafen
Cyetpyrafen is a pyrazole insecticide/acaricide with broad-spectrum insecticidal activity. Cyetpyrafen binds to DhelOBP4 (Ki = 4.95 μM) and DhelOBP21 (Ki = 5.51 μM) to mediate olfactory recognition in *Cryptolaemus montrouzieri*. Cyetpyrafen induces dose-dependent electroantennogram responses in *Cryptolaemus montrouzieri* and exhibits repellent effects on the species. Cyetpyrafen has bioaccumulative properties, is rapidly and passively absorbed by the roots of lettuce and rice, reaches a steady state within 24 h, preferentially accumulates in roots, and shows limited xylem/phloem translocation.
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- CAS No.: 1253429-01-4
- 화학식: C24H31N3O2
- 분자량:393.53
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
제품 설명
In Vitro
Cyetpyrafen (1.12 mg/L; 1-96 h) is rapidly taken up by Oryza sativa (rice) and Lactuca sativa (lettuce) roots, reaching steady state within 24 h, with preferential accumulation in roots (average RCFs 1290 mL/g for rice, 1730 mL/g for lettuce) and poor translocation to shoots, and is eliminated more slowly from lettuce roots than rice roots[2].
Cyetpyrafen (5 mg/L; 3-96 h) does not undergo phloem-mediated translocation in Oryza sativa seedlings, as it cannot migrate from exposed roots to unexposed roots or shoots[2].
Cyetpyrafen (1.12 mg/L; 24-96 h) exposure induces significant increases in the activities of CYP450, POD, CarE, GT, and GST in rice and lettuce roots, indicating these enzymes mediate the metabolic transformation of cyetpyrafen in plants[2].
Cyetpyrafen is predicted to be very toxic to fish and highly toxic to daphnid and green algae, with several of its phase I metabolites (M-391, M-409-1/2, M-407) exhibiting similar ecotoxicity levels, while phase II metabolites show reduced toxicity[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1253429-01-4
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분자량 393.53
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화학식 C24H31N3O2
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SMILES
C(=C(\C#N)/C1=CC=C(C(C)(C)C)C=C1)(\OC(C(C)(C)C)=O)/C=2N(CC)N=C(C)C2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Mao Z, et al. Cyetpyrafen, chlorfenapyr and spirodiclofen affect the olfactory recognition of Dastarcus helophoroides by acting on DhelOBP4 and DhelOBP21. Pestic Biochem Physiol. 2025;214:106568. [Content Brief]
[2]. Li R, et al. Insight into the uptake and metabolism of a new insecticide cyetpyrafen in plants. Environ Int. 2022;169:107522. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)