V-ATPase-IN-1
Based on 1 Customer Validation
V-ATPase-IN-1 (Compound 3b-03) is a Vacuolar-type H+-ATPases (V-ATPase) inhibitor (IC50 = 194.80 μM) that can effectively target the V-ATPase subunit A (Kd = 0.803 μM). V-ATPase-IN-1 exhibits insecticidal activity against M. separata (LC50 = 2.64 mM) and contributes to research in the development of chemical insecticides.
For research use only. We do not sell to patients.
- Purity: 99.23%
- CAS No.: 1243603-61-3
- Formula: C21H20ClNO2
- Molecular Weight:353.84
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
IC50: 194.8 μM (V-ATPase)[1].
Chemical Information
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CAS No. 1243603-61-3
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Appearance Solid
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Molecular Weight 353.84
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Formula C21H20ClNO2
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Color White to off-white
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SMILES
ClC1=CC(CNC2=CC=CC=C2)=CC(OC)=C1OCC3=CC=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (353.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8261 mL | 14.1307 mL | 28.2614 mL | 70.6534 mL |
| 5 mM | 0.5652 mL | 2.8261 mL | 5.6523 mL | 14.1307 mL | |
| 10 mM | 0.2826 mL | 1.4131 mL | 2.8261 mL | 7.0653 mL | |
| 15 mM | 0.1884 mL | 0.9420 mL | 1.8841 mL | 4.7102 mL | |
| 20 mM | 0.1413 mL | 0.7065 mL | 1.4131 mL | 3.5327 mL | |
| 25 mM | 0.1130 mL | 0.5652 mL | 1.1305 mL | 2.8261 mL | |
| 30 mM | 0.0942 mL | 0.4710 mL | 0.9420 mL | 2.3551 mL | |
| 40 mM | 0.0707 mL | 0.3533 mL | 0.7065 mL | 1.7663 mL | |
| 50 mM | 0.0565 mL | 0.2826 mL | 0.5652 mL | 1.4131 mL | |
| 60 mM | 0.0471 mL | 0.2355 mL | 0.4710 mL | 1.1776 mL | |
| 80 mM | 0.0353 mL | 0.1766 mL | 0.3533 mL | 0.8832 mL | |
| 100 mM | 0.0283 mL | 0.1413 mL | 0.2826 mL | 0.7065 mL |