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  3. SCPI-1

SCPI-1 is a potent and competitive mosquito sterol carrier protein-2 (SCP-2) inhibitor (AeSCP-2 IC50 = 0.347 µM; AeSCP-x IC50 = 0.527 µM). SCPI-1 exhibits physiological effects on cholesterol metabolism in cultured insect cells (IC50 of 5.53 µM in Aag-2 cells). SCPI-1 shows insecticidal activity against Aedes aegypti with a LD50 of 4.8 µM.

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SCPI-1

SCPI-1 Chemical Structure

CAS No. : 339231-67-3

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Description

SCPI-1 is a potent and competitive mosquito sterol carrier protein-2 (SCP-2) inhibitor (AeSCP-2 IC50 = 0.347 µM; AeSCP-x IC50 = 0.527 µM). SCPI-1 exhibits physiological effects on cholesterol metabolism in cultured insect cells (IC50 of 5.53 µM in Aag-2 cells). SCPI-1 shows insecticidal activity against Aedes aegypti with a LD50 of 4.8 µM[1].

Molecular Weight

378.28

Formula

C17H13Cl2N3OS

CAS No.
SMILES

O=C(C)NC1=CC=C(NC2=NC(C3=CC(Cl)=C(Cl)C=C3)=CS2)C=C1

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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SCPI-1 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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SCPI-1
Cat. No.:
HY-180460
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