339231-67-3
339231-67-3
Chemical Structure
SCPI-1
- CAS No.: 339231-67-3
- Formula:C17H13Cl2N3OS
- Molecular Weight:378.28
InChIKey: XDFHOEGHGGFQKU-UHFFFAOYSA-N
SMILES: O=C(C)NC1=CC=C(NC2=NC(C3=CC(Cl)=C(Cl)C=C3)=CS2)C=C1
Biological Activity: SCPI-1 is a potent and competitive mosquito sterol carrier protein-2 (SCP-2) inhibitor (AeSCP-2 IC50 = 0.347 µM; AeSCP-x IC50 = 0.527 µM). SCPI-1 exhibits physiological effects on cholesterol metabolism in cultured insect cells (IC50 of 5.53 µM in Aag-2 cells). SCPI-1 shows insecticidal activity against Aedes aegypti with a LD50 of 4.8 µM[1].
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SCPI-1 | SCPI-1 is a potent and competitive mosquito sterol carrier protein-2 (SCP-2) inhibitor (AeSCP-2 IC50 = 0.347 µM; AeSCP-x IC50 = 0.527 µM). SCPI-1 exhibits physiological effects on cholesterol metabolism in cultured insect cells (IC50 of 5.53 µM in Aag-2 cells). SCPI-1 shows insecticidal activity against Aedes aegypti with a LD50 of 4.8 µM. | |||||||||||||||||||||
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