Insecticidal agent 31 

Insecticidal agent 31 is an insecticide targeting the γ-aminobutyric acid receptor (GABAR). Insecticidal agent 31 exhibits insecticidal activity against Plutella xylostella, Spodoptera frugiperda and Spodoptera exigua. Insecticidal agent 31 can serve as a lead compound for the design and synthesis of novel isoxazole-based insecticides^[1].

Insecticidal agent 31 (S-19) (0.1-10 mg/L; topical exposure via treated cabbage leaves; single administration) exhibits potent insecticidal activity against third-instar Plutella xylostella larvae, with 100% mortality at 10 mg/L and 1 mg/L, 90% mortality at 0.1 mg/L, and an LC₅₀ of 0.24 mg/L^[1].
Insecticidal agent 31 (S-19) (0.94 mg/L; topical exposure via treated cabbage leaves; single administration) exhibits insecticidal activity against third-instar Spodoptera frugiperda larvae, with an LC₅₀ of 0.94 mg/L^[1].
Insecticidal agent 31 (S-19) (0.89 mg/L; topical exposure via treated cabbage leaves; single administration) exhibits insecticidal activity against third-instar Spodoptera exigua larvae, with an LC₅₀ of 0.89 mg/L^[1].
Insecticidal agent 31 (S-19) (6.43 mg/L; topical exposure via treated cabbage leaves; single administration) exhibits weak insecticidal activity against third-instar Spodoptera litura larvae, with an LC₅₀ of 6.43 mg/L^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

591.33

C₂₁H₁₅Cl₂F₇N₄O₂S

ClC1=C(F)C(Cl)=CC([C@]2(C(F)(F)F)CC(C3=CC=C(C(NNC(NCC(F)(F)F)=S)=O)C(C)=C3)=NO2)=C1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Sun XL, et al. Design, Synthesis, and Insecticidal Activity of Novel Chiral Isoxazoline Thiourea Derivatives. J Agric Food Chem. 2026;74(11):9795-9802.  [Content Brief]