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Results for "

(3S,5R)-XU 62-320-d6

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (2) Aldose Reductase (1) Amine N-methyltransferase (1) Antibiotic (1) Apoptosis (8) Atg4 (1) Autophagy (9) Bacterial (2) Biochemical Assay Reagents (4) Calcium Channel (1) CaMK (1) Carbonic Anhydrase (1) Casein Kinase (1) CDK (3) Cholinesterase (ChE) (1) DNA/RNA Synthesis (1) Dopamine Receptor (2) Drug Derivative (1) Endogenous Metabolite (4) Environmental Pollutants (2) Estrogen Receptor/ERR (3) FAK (1) Ferroptosis (5) Fluorescent Dye (5) GPR84 (1) GSK-3 (3) HCV Protease (1) HMG-CoA Reductase (HMGCR) (9) Influenza Virus (1) Integrin (1) Interleukin Related (1) Isotope-Labeled Compounds (5) Ligands for E3 Ligase (1) MicroRNA (20) Mitochondrial Metabolism (1) MMP (1) Necroptosis (1) Parasite (2) PDK-1 (1) Phosphodiesterase (PDE) (2) PKC (1) PKG (1) PPAR (1) PROTACs (1) Reactive Oxygen Species (ROS) (3) Reference Standards (12) RIP kinase (1) ROR (1) Ser/Thr Protease (1) Small Interfering RNA (siRNA) (4) Sodium Channel (2) Src (1) TRP Channel (1) β-catenin (1)
By Research Areas:	Cancer (56) Cardiovascular Disease (14) Endocrinology (3) Infection (8) Inflammation/Immunology (12) Metabolic Disease (4) Neurological Disease (8)
Oligonucleotides:	Antioxidants (1) miRNA mimics (5) miRNA antagomirs (5) miRNA agomirs (5) MicroRNAs (20) Rat Pre-designed siRNA Sets (1) miRNA inhibitors (5) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (2) Cholesterol (1) siRNAs (4)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14664

Fluvastatin 15+ Cited Publications XU 62-320 free acid	HMG-CoA Reductase (HMGCR) Autophagy	Cardiovascular Disease Cancer
Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC₅₀ of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .

HY-14664A

Fluvastatin sodium 15+ Cited Publications XU 62-320	HMG-CoA Reductase (HMGCR) Autophagy Ferroptosis	Cardiovascular Disease Cancer
Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC₅₀ of 8 nM. Fluvastatin sodium protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .

HY-10580

GSK 3 Inhibitor IX 15+ Cited Publications 6-Bromoindirubin-3'-oxime; BIO; MLS 2052	GSK-3 CDK Apoptosis	Cancer
GSK 3 Inhibitor IX (6-Bromoindirubin-3'-oxime; BIO) is a potent, selective, reversible and ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex with IC₅₀s of 5 nM/320 nM/80 nM for (GSK-3α/β)/CDK1/CDK5, respectively.

HY-N0102

Isoliquiritigenin Maximum Cited Publications 31 Publications Verification GU17; ISL; Isoliquiritigen; SJ000286237	Aldose Reductase Influenza Virus Autophagy Apoptosis	Infection Inflammation/Immunology Cancer
Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza uralensis Fisch., which inhibits aldose reductase with an IC₅₀ of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC₅₀ of 24.7 μM.

HY-B1066

Butylhydroxyanisole 5 Publications Verification Butylated hydroxyanisole; E320	Environmental Pollutants Reactive Oxygen Species (ROS) Ferroptosis	Neurological Disease Inflammation/Immunology
Butylhydroxyanisole (Butylated hydroxyanisole) is an antioxidant used as a food additive preservative. Butylhydroxyanisole mediates liver toxicity, retardation in reproductive organ development and learning, and sleep deficit. Butylhydroxyanisole exerts neurotoxic effects and leads to disruption of the brain and nerve development . Butylhydroxyanisole is a ferroptosis inducer .

HY-N0233

Bavachin 10+ Cited Publications Corylifolin	Estrogen Receptor/ERR	Cancer
Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC₅₀s of 320 and 680 nM, respectively.

HY-N0171B

Beta-Sitosterol (purity>75%) β-Sitosterol (purity>75%); 22,23-Dihydrostigmasterol (purity>75%)	Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
Beta-Sitosterol (purity>75%) is a phytosterol with oral activity. Beta-Sitosterol (purity>75%) interferes with a variety of cell signaling pathways, including the cell cycle, apoptosis and cell proliferation. Beta-Sitosterol (purity>75%) has anti-inflammatory, antioxidant, and antitumor activities .

HY-15898

Y-320 5 Publications Verification	Interleukin Related Apoptosis	Inflammation/Immunology Cancer
Y-320 is a potent, orally active phenylpyrazoleanilide immunomodulator. Y-320 inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC₅₀ values of 20 to 60 nM. Y-320 enhances TP53, DMD, and COL17A1 PTC readthrough by G418 and increases cellular protein levels and protein synthesis. Y-320 concomitants use of with a low dose of Paclitaxel (HY-B0015) significantly sensitized multidrug resistance (MDR) tumors by inducing G2/M phase arrest and apoptosis. Y-320 can be used for research of rheumatoid arthritis (RA) and cancer .

HY-16998

SR2211 1 Publications Verification	ROR	Inflammation/Immunology
SR2211 is a potent, selective synthetic RORγ modulator and functions as an inverse agonist, with a K_i of 105 nM and an IC₅₀ of ~320 nM.

HY-P1883A

Bacterial Sortase Substrate III, Abz/DNP TFA	Fluorescent Dye	Infection
Bacterial Sortase Substrate III, Abz/DNP TFA is a fluorescent peptide substrate. Bacterial Sortase Substrate III, Abz/DNP TFA undergoes cleavage catalyzed by Staphylococcus aureus sortase A (SrtAΔN24) and Streptococcus pyogenes sortase A (SrtAΔN81), and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of the cell wall cross-bridge. Cleavage of this substrate can be detected at Ex/Em=320 nm/420 nm .

HY-14858

Derenofylline 2 Publications Verification SLV 320	Adenosine Receptor	Cardiovascular Disease
Derenofylline (SLV 320) is a potent, selective and orally active adenosine A₁ receptor antagonist, with K_i values of 1 nM, 200 nM and 398 nM for human A₁, A₃ and A_2A receptors respectively. Derenofylline suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats .

HY-117095

4-Methylumbelliferyl oleate	Fluorescent Dye	Metabolic Disease
4-Methylumbelliferyl oleate is a fluorogenic substrate for acid and alkaline lipases. 4-Methylumbelliferyl oleate is cleaved by lipases, liberating 4-Methylumbelliferyl (Ex/Em=320/450 nm) .

HY-B1196

Tiapride hydrochloride	Dopamine Receptor	Neurological Disease
Tiapride hydrochloride is a selective and orally active D₂ and D₃ dopamine receptors antagonist with IC₅₀ values of 110-320 nM and 180 nM, respectively. Tiapride hydrochloride shows anti-dyskinetic activity and anxiolytic activity. Tiapride hydrochloride is a neuroleptic agent .

HY-128464

LL320	Amine N-methyltransferase	Metabolic Disease
LL320 is a selective NNMT inhibitor with a K_i,app of 6.8 nM. LL320 exhibits interactions with RNMT, DPH₅, and SAHH .

HY-W006492

5a-Pregnane-3,20-dione 1 Publications Verification	Endogenous Metabolite	Endocrinology Cancer
5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.

HY-B0897

Bisoctrizole 1 Publications Verification	Biochemical Assay Reagents	Others
Bisoctrizole is a broad-spectrum UVA/UVB absorber that belongs to the benzotriazole class of compounds. Bisoctrizole absorbs UV light through hydroxyphenyl groups, causing reversible electronic transitions, thereby converting light energy into heat energy, inhibiting UV-induced material or skin damage. Bisoctrizole is highly efficient in capturing UVA (320-400 nm) and some UVB (280-320 nm) radiation. Bisoctrizole delays the photodegradation of materials such as silicones, improving their UV aging resistance or enhancing the photoprotective ability of sunscreen products .

HY-17445

Muraglitazar BMS-298585	PPAR	Metabolic Disease
Muraglitazar is a PPAR α/γ dual agonist for the research of type 2 diabetes and associated dyslipidemia. Muraglitazar shows potent activity in vitro at human PPARα (EC₅₀ = 320 nM) and PPARγ(EC₅₀ = 110 nM) .

HY-104000

BAY-320	Ser/Thr Protease	Cancer
BAY-320 is a selective and ATP-competitive Bub1 inhibitor that inhibits the kinase activity of Bub1 with an IC₅₀ of 680 nM. BAY-320 inhibits endogenous Bub1-mediated Sgo1 localization. BAY-320 affects cellular mitotic chromosome arrangement and spindle assembly. BAY-320 inhibits cell proliferation. BAY-320 can be used in the study of cancer such as ovarian cancer and cervical cancer .

HY-112711

LV-320	Atg4 Autophagy	Cancer
LV-320 is a potent and uncompetitive ATG4B inhibitor with an IC₅₀ of 24.5 μM and a K_d of 16 μM. LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flux in cells, and is stable, non-toxic and active in vivo .

HY-116448

Metaflumizone BAS-320I	Environmental Pollutants Parasite Sodium Channel	Infection
Metaflumizone is a semicarbazone insecticide, acts as a potent sodium channel blocker .

HY-137295

Ingenol 3,20-dibenzoate	PKC Apoptosis	Inflammation/Immunology
Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-γ production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells .

HY-117605

N-Desmethyl Sildenafil Desmethylsildenafil; UK-103,320	Phosphodiesterase (PDE)	Cardiovascular Disease
N-Desmethyl Sildenafil (Desmethylsildenafil) is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor .

HY-10515

BX-320	PDK-1	Cancer
BX-320 is a selective, ATP-competitive, orally acitive, and direct PDK1 inhibitor with an IC₅₀ of 30 nM in a direct kinase assay format. BX-320 also induces apoptosis. Anticancer effect .

HY-R00674

*hsa-miR-320c mimic*	MicroRNA	Cancer
hsa-miR-320c mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-320c mimic hsa-miR-320c mimic

HY-R00671

*hsa-miR-320a-3p mimic*	MicroRNA	Cancer
hsa-miR-320a-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-320a-3p mimic hsa-miR-320a-3p mimic

HY-W006492S

5a-Pregnane-3,20-dione-d6	Endogenous Metabolite	Endocrinology Cancer
5a-Pregnane-3,20-dione-d₆ is the deuterium labeled 5a-Pregnane-3,20-dione. 5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.

HY-B1066R

Butylhydroxyanisole (Standard) Butylated hydroxyanisole (Standard); E320 (Standard)	Reference Standards Reactive Oxygen Species (ROS) Ferroptosis	Neurological Disease Inflammation/Immunology
Butylhydroxyanisole (Standard) is the analytical standard of Butylhydroxyanisole. This product is intended for research and analytical applications. Butylhydroxyanisole (Butylated hydroxyanisole) is an antioxidant used as a food additive preservative. Butylhydroxyanisole mediates liver toxicity, retardation in reproductive organ development and learning, and sleep deficit. Butylhydroxyanisole exerts neurotoxic effects and leads to disruption of the brain and nerve development . Butylhydroxyanisole is a ferroptosis inducer .

HY-14664AS

Fluvastatin-d6 sodium XU 62-320-d₆	HMG-CoA Reductase (HMGCR) Autophagy	Cardiovascular Disease Cancer
Fluvastatin-d₆ (sodium) is deuterium labeled Fluvastatin sodium. Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.

HY-RI00674

*hsa-miR-320c inhibitor*	MicroRNA	Cancer
hsa-miR-320c inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-320c inhibitor hsa-miR-320c inhibitor

HY-N7262

Hydroxyvalerenic acid	Others	Cancer
Hydroxyvalerenic acid is isolated from Verbena officinalis, has a low toxicity with IC₅₀ values of 123 and 165 μM against GLC4 and COLO 320 cells, respectively .

HY-117605R

N-Desmethyl Sildenafil (Standard) Desmethylsildenafil (Standard); UK-103,320 (Standard)	Reference Standards Phosphodiesterase (PDE)	Cardiovascular Disease
N-Desmethyl Sildenafil (Standard) is the analytical standard of N-Desmethyl Sildenafil. This product is intended for research and analytical applications. N-Desmethyl Sildenafil (Desmethylsildenafil) is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor .

HY-P1883

Bacterial Sortase Substrate III, Abz/DNP	Fluorescent Dye	Infection
Bacterial Sortase Substrate III, Abz/DNP is a fluorescent peptide substrate. Bacterial Sortase Substrate III, Abz/DNP undergoes cleavage catalyzed by Staphylococcus aureus sortase A (SrtAΔN24) and Streptococcus pyogenes sortase A (SrtAΔN81), and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of the cell wall cross-bridge. Cleavage of this substrate can be detected at Ex/Em=320 nm/420 nm .

HY-110270

RN-9893	TRP Channel	Inflammation/Immunology
RN-9893 is a potent and selective TRPV4 receptor antagonist with IC₅₀ values of 320, 420 and 660 nM for mouse, human and rat channels, respectively .

HY-B1196A

Tiapride	Dopamine Receptor	Neurological Disease
Tiapride is a selective and orally active D₂ and D₃ dopamine receptors antagonist with IC₅₀ values of 110-320 nM and 180 nM, respectively. Tiapride shows anti-dyskinetic activity and anxiolytic activity. Tiapride is a neuroleptic agent .

HY-174820

AZ'320	Necroptosis RIP kinase	Inflammation/Immunology Cancer
AZ'320 is an ATP-competitive necroptosis (EC₅₀ of 4.9 μM) inhibitor and a RIPK1 (pK_D of 5.45) inhibitor. AZ'320 inhibits necroptosis by inhibiting RIPK1 phosphorylation. AZ’320 prevents mortality of the mice and rescues temperature and body weight in SIRS mice models. AZ'320 can be used for researches of cancer and inflammation .

HY-19557

IDX-320	Drug Derivative HCV Protease	Infection
IDX-320 is a Pipecolic acid (HY-Y0669) derivative. IDX-320 inhibits NS3/4a proteases across genotypes 1a, 1b, 2a, and 4a with an IC₅₀ 0.8-1.9 nM. IDX-320 can be used in the research of HCV infection .

HY-P10316

*CaMKI(299-320)* Calmodulin-Dependent Protein Kinase I (299-320) Binding Domain	CaMK	Others
CaMKI (299-320) refers to a peptide consisting of residues 299-320 of Calcium/calmodulin-dependent protein kinase I (CaMKI). CaMKI (299-320), as a protein kinase, has a high affinity interaction with Ca ²⁺-CAM (K_d≤1 nM≤1 nM), which can phosphorylate specific substrate proteins, thereby regulating their activity. CaMKI (299-320) contains the CAM-binding domain and the self-inhibition domain, and CaMKI (299-320) can be used to study cell physiological processes, including cell proliferation, differentiation, and apoptosis .

HY-120917

BRD1172 ML320	GSK-3 β-catenin	Cardiovascular Disease Neurological Disease Cancer
BRD1172 (ML320) is a selectivity GSK3β inhibitor with an IC₅₀ of 24 nM for GSK3β over CDK5. BRD1172 significantly inhibits GSK3β-mediated Tau phosphorylation in SH-SY5Y cells, and relieves negative regulation by GSK3β on β-catenin degradation and TCF/LEF promoter activities. BRD1172 can be used for Alzheimer’s disease, cardiac hypertrophy and cancers research .

HY-14664R

Fluvastatin (Standard) XU 62-320 free acid (Standard)	HMG-CoA Reductase (HMGCR) Autophagy Reference Standards	Cardiovascular Disease Cancer
Fluvastatin (Standard) is the analytical standard of Fluvastatin. This product is intended for research and analytical applications. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .

HY-14664B

(3R,5S)-Fluvastatin (3R,5S)-XU 62-320 free acid	HMG-CoA Reductase (HMGCR) Autophagy	Cardiovascular Disease Cancer
(3R,5S)-Fluvastatin is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC₅₀ of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .

HY-14664C

(3S,5R)-Fluvastatin sodium (3S,5R)-XU 62-320	HMG-CoA Reductase (HMGCR)	Cardiovascular Disease Cancer
(3S,5R)-Fluvastatin sodium ((3S,5R)-XU 62-320) is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC₅₀ of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .

HY-14664AR

Fluvastatin sodium (Standard) XU 62-320 (Standard)	Reference Standards HMG-CoA Reductase (HMGCR) Autophagy Ferroptosis	Cardiovascular Disease Cancer
Fluvastatin (sodium) (Standard) is the analytical standard of Fluvastatin (sodium). This product is intended for research and analytical applications. Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC₅₀ of 8 nM. Fluvastatin sodium protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .

HY-175012

PIF1-IN-1	DNA/RNA Synthesis	Others
PIF1-IN-1 (Compound 48) is an inhibitor of hPIF1 helicase (IC₅₀ = 320 μM) .

HY-161682

GPR84 antagonist 9	GPR84	Neurological Disease
GPR84 antagonist 9 (compound 320) is an orally active GPR84 antagonist with the IC₅₀ of 0.012 μM. GPR84 antagonist 9 can be used for study of inflammatory-driven pain diseases .

HY-172627

Rhod-FF tripotassium	Fluorescent Dye Calcium Channel	Others
Rhod-FF tripotassium is a Rhod-2 derivative and cell-impermeant calcium indicator (K_d of 320 μM). Rhod-FF tripotassium indicates calcium concentration by fluorescence upon binding to calcium ions, with excitation at 552 nm and emission at 580 nm .

HY-113096

Prostaglandin D1 PGD1	Endogenous Metabolite	Metabolic Disease
Prostaglandin D1 is a prostanoid which causes contractile and relaxant on isolated human pial arteries, it is also an inhibitor of ADP-induced platelet aggregation with an IC₅₀ value of 320 ng/ml. Prostaglandin D1 can be used for metabolic research .

HY-R00673

*hsa-miR-320b mimic*	MicroRNA	Cancer
hsa-miR-320b mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-320b mimic hsa-miR-320b mimic

HY-R00675

*hsa-miR-320e mimic*	MicroRNA	Cancer
hsa-miR-320e mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-320e mimic hsa-miR-320e mimic

HY-R00672

*hsa-miR-320a-5p mimic*	MicroRNA	Cancer
hsa-miR-320a-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-320a-5p mimic hsa-miR-320a-5p mimic

HY-RS17653

Cd320 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Cd320 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd320 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cd320 Mouse Pre-designed siRNA Set A Cd320 Mouse Pre-designed siRNA Set A

Cat. No.	Product Name	Target	Research Area

HY-P1883A

Bacterial Sortase Substrate III, Abz/DNP TFA	Fluorescent Dye	Infection
Bacterial Sortase Substrate III, Abz/DNP TFA is a fluorescent peptide substrate. Bacterial Sortase Substrate III, Abz/DNP TFA undergoes cleavage catalyzed by Staphylococcus aureus sortase A (SrtAΔN24) and Streptococcus pyogenes sortase A (SrtAΔN81), and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of the cell wall cross-bridge. Cleavage of this substrate can be detected at Ex/Em=320 nm/420 nm .

HY-P1883

Bacterial Sortase Substrate III, Abz/DNP	Fluorescent Dye	Infection
Bacterial Sortase Substrate III, Abz/DNP is a fluorescent peptide substrate. Bacterial Sortase Substrate III, Abz/DNP undergoes cleavage catalyzed by Staphylococcus aureus sortase A (SrtAΔN24) and Streptococcus pyogenes sortase A (SrtAΔN81), and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of the cell wall cross-bridge. Cleavage of this substrate can be detected at Ex/Em=320 nm/420 nm .

HY-P10316

*CaMKI(299-320)* Calmodulin-Dependent Protein Kinase I (299-320) Binding Domain	CaMK	Others
CaMKI (299-320) refers to a peptide consisting of residues 299-320 of Calcium/calmodulin-dependent protein kinase I (CaMKI). CaMKI (299-320), as a protein kinase, has a high affinity interaction with Ca ²⁺-CAM (K_d≤1 nM≤1 nM), which can phosphorylate specific substrate proteins, thereby regulating their activity. CaMKI (299-320) contains the CAM-binding domain and the self-inhibition domain, and CaMKI (299-320) can be used to study cell physiological processes, including cell proliferation, differentiation, and apoptosis .

HY-P2192

JMV-320	Peptides	Others
JMV-320 is an active compound.

HY-P10677

HB-3-20	Integrin	Cancer
HB-3-20 leads to degradation of the cell surface integrin α_Vβ₅. Transglutaminase 2 (TG2) has specificity for HB-3-20 (k_cat/K_M=0.16 μM ^-1min ^-1) .

HY-P11715

Abz-GFDPFRQ-EDDnp	Fluorescent Dye	Neurological Disease
Abz-GFDPFRQ-EDDnp is a fluorogenic substrate for metallothionein oligopeptidase (λ_ex=320 nm, λ_em=420 nm). Abz-GFDPFRQ-EDDnp is used to determine the enzymatic activity of metallothionein oligopeptidase in tissue extracts and for research on temporal lobe epilepsy .

HY-P11034

BPDEtide	PKG	Inflammation/Immunology
BPDEtide is a synthetic peptide. BPDEtide has apparent Km values of 68 and 320 μM for cGK and cAK, respectively. BPDEtide is the most selective peptide substrate for measuring cGK activity .

Cat. No.	Product Name	Target	Research Area	Image

HY-P990515

Anti-TCR Antibody (NKTT320) NKTT320	Inhibitory Antibodies	Inflammation/Immunology
Anti-TCR Antibody (NKTT320) is a humanized antibody expressed in CHO, targeting TCR. Anti-TCR Antibody (NKTT320) features huIgG4 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-TCR Antibody (NKTT320) can refer to Human IgG4 kappa, Isotype Control (HY-P99003).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0102

Isoliquiritigenin Maximum Cited Publications 31 Publications Verification GU17; ISL; Isoliquiritigen; SJ000286237	Classification of Application Fields Plants Infection Chalcones Flavonoids Microorganisms Leguminosae Phenols Polyphenols Glycyrrhiza uralensis Fisch. Inflammation/Immunology Disease Research Fields Source Classification	Aldose Reductase Influenza Virus Autophagy Apoptosis
Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza uralensis Fisch., which inhibits aldose reductase with an IC₅₀ of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC₅₀ of 24.7 μM.

HY-N0233

Bavachin 10+ Cited Publications Corylifolin	Flavonoids Classification of Application Fields Leguminosae Flavonones Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields Source Classification Cancer	Estrogen Receptor/ERR
Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC₅₀s of 320 and 680 nM, respectively.

HY-N0171B

Beta-Sitosterol (purity>75%) β-Sitosterol (purity>75%); 22,23-Dihydrostigmasterol (purity>75%)	Cardiovascular Disease Structural Classification other families Classification of Application Fields Plants Inflammation/Immunology Disease Research Fields Steroids Source Classification	Apoptosis
Beta-Sitosterol (purity>75%) is a phytosterol with oral activity. Beta-Sitosterol (purity>75%) interferes with a variety of cell signaling pathways, including the cell cycle, apoptosis and cell proliferation. Beta-Sitosterol (purity>75%) has anti-inflammatory, antioxidant, and antitumor activities .

HY-W006492

5a-Pregnane-3,20-dione 1 Publications Verification	Structural Classification Classification of Application Fields Disease markers Nervous System Disorder Endogenous metabolite Disease Research Fields Steroids Source Classification Cancer	Endogenous Metabolite
5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.

HY-137295

Ingenol 3,20-dibenzoate	Classification of Application Fields Terpenoids Diterpenoids Euphorbia esula L. Euphorbiaceae Plants Inflammation/Immunology Disease Research Fields Source Classification	PKC Apoptosis
Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-γ production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells .

HY-N7262

Hydroxyvalerenic acid	Classification of Application Fields Ketones, Aldehydes, Acids Valeriana officinalis Linn. Plants Valerianaceae Disease Research Fields Cancer Source Classification	Others
Hydroxyvalerenic acid is isolated from Verbena officinalis, has a low toxicity with IC₅₀ values of 123 and 165 μM against GLC4 and COLO 320 cells, respectively .

HY-N10363

Pixinol	Triterpenes Classification of Application Fields Juglandaceae Terpenoids Cyclocarya paliurus (Batal.) Iljinsk. Plants Disease Research Fields Cancer Source Classification	Others
Pixinol, a natural glycoside, shows cytotoxicity against the human lung carcinoma GLC4 and adenocarcinoma COLO 320 cell lines (IC₅₀=71 µM and 43 µM, respectively) .

HY-W006492R

5a-Pregnane-3,20-dione (Standard)	Structural Classification Disease markers Nervous System Disorder Endogenous metabolite Steroids Source Classification	Reference Standards Endogenous Metabolite
5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.

HY-N0233R

Bavachin (Standard) Corylifolin (Standard)	Structural Classification Flavonoids Leguminosae Flavonones Phenols Polyphenols Psoralea corylifolia L. Plants Source Classification	Reference Standards Estrogen Receptor/ERR
Bavachin (Standard) is the analytical standard of Bavachin. This product is intended for research and analytical applications. Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively.

HY-N7262R

Hydroxyvalerenic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Valeriana officinalis Linn. Plants Valerianaceae Source Classification	Reference Standards Others
Hydroxyvalerenic acid (Standard) is the analytical standard of Hydroxyvalerenic acid. This product is intended for research and analytical applications. Hydroxyvalerenic acid is isolated from Verbena officinalis, has a low toxicity with IC50 values of 123 and 165 μM against GLC4 and COLO 320 cells, respectively .

Species:	Human (1) Rat (1) Mouse (3)
Tag:	His (3) Fc (2)
Source:	HEK293 (5)

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HY-P72456

	TCblR/CD320 Protein, Human (HEK293, His) CD320 antigen; 8D6 antigen; FDC-signaling molecule 8D6; FDC-SM-8D6; Transcobalamin receptor; TCblR; CD320	Human	HEK293
	TCblR/CD320 is the receptor for cobalamin (TCbl) and is critical for cellular cobalamin homeostasis and B cell responses. It is expressed on follicular dendritic cells, interacts with germinal center B cells, and coordinates immune responses. TCblR/CD320 Protein, Human (HEK293, His) is the recombinant human-derived TCblR/CD320 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P76798

	TCblR/CD320 Protein, Mouse (HEK293, His) CD320 antigen; 8D6 antigen; FDC-signaling molecule 8D6; FDC-SM-8D6; Transcobalamin receptor; TCblR; CD320	Mouse	HEK293
	The TCblR/CD320 protein is a receptor for cobalamin-saturated transcobalamin (TCbl) that plays a key role in cobalamin uptake and is expressed on the plasma membrane, especially on follicular dendritic cells (FDCs). As a costimulator, TCblR promotes B cell responses, promoting differentiation and proliferation. TCblR/CD320 Protein, Mouse (HEK293, His) is the recombinant mouse-derived TCblR/CD320 protein, expressed by HEK293 , with C-His labeled tag.

HY-P76797

	TCblR/CD320 Protein, Mouse (HEK293, Fc) CD320 antigen; 8D6 antigen; FDC-signaling molecule 8D6; FDC-SM-8D6; Transcobalamin receptor; TCblR; CD320	Mouse	HEK293
	The TCblR/CD320 protein is a receptor for cobalamin-saturated transcobalamin (TCbl) that plays a key role in cobalamin uptake and is expressed on the plasma membrane, especially on follicular dendritic cells (FDCs). As a costimulator, TCblR promotes B cell responses, promoting differentiation and proliferation. TCblR/CD320 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived TCblR/CD320 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P76226

	TCblR/CD320 Protein, Rat (HEK293, Fc) CD320 antigen; 8D6 antigen; FDC-signaling molecule 8D6; FDC-SM-8D6; Transcobalamin receptor	Rat	HEK293
	The TCblR/CD320 protein is a receptor for cobalamin-saturated transcobalamin (TCbl) and is critical for cobalamin uptake and can influence cell physiology. At the plasma membrane, it is expressed on follicular dendritic cells (FDC), where it helps interact with germinal center B cells and promotes immune responses. TCblR/CD320 Protein, Rat (HEK293, Fc) is the recombinant rat-derived TCblR/CD320 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P78049

	VLDLR Protein, Mouse (HEK293, His) VLDL-R; VLDLR; RP11-320E16.1; CHRMQ1; FLJ35024; VLDLRCH	Mouse	HEK293
	VLDLR protein is a multifunctional cell surface receptor that plays a crucial role in energy metabolism by binding VLDL and promoting cellular uptake through endocytosis.In addition to lipid transport, VLDLR has broad binding affinities for molecules such as Reelin/RELN, APOE, and CLU.VLDLR Protein, Mouse (HEK293, His) is the recombinant mouse-derived VLDLR protein, expressed by HEK293 , with C-His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-W006492S

5a-Pregnane-3,20-dione-d6
5a-Pregnane-3,20-dione-d₆ is the deuterium labeled 5a-Pregnane-3,20-dione. 5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.

HY-14664AS

Fluvastatin-d6 sodium
Fluvastatin-d₆ (sodium) is deuterium labeled Fluvastatin sodium. Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.

HY-W018151S

2-Benzotriazol-2-yl-4,6-di-tert-butylphenol-d4
2-Benzotriazol-2-yl-4,6-di-tert-butylphenol-d₄ (UV-320-d₄) is deuterium labeled 2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4,6-di-tert-butylphenol .

HY-154743S

4-Pregnen-11β,21-diol-3,20-dione-d8
4-Pregnen-11β,21-diol-3,20-dione-d₈ is deuterated labeled 4-Pregnen-11β,21-diol-3,20-dione.

HY-B0242S1

Sulfanilamide-d4
Sulfanilamide-d₄ is the deuterium labeled Sulfanilamide. Sulfanilamide is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.

HY-131332S1

N-Desmethyl ulipristal acetate-d3
N-Desmethyl ulipristal-d₃ ((11β)-11-[4-(Methylamino)phenyl]-3,20-dioxo-19-norpregna-4,9-dien-17-yl-d₃) acetate is deuterium labeled N-Desmethyl ulipristal acetate ((11β)-11-[4-(Methylamino)phenyl]-3,20-dioxo-19-norpregna-4,9-dien-17-yl) .

HY-146638S

5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5-d4
5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5-d₄ is the deuterium labeled 5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5 .

HY-178425S

Butylhydroxyanisole-d24

Butylhydroxyanisole-d₂₄ (Butylated hydroxyanisole-d₂₄) is the deuterium labeled Butylhydroxyanisole (HY-B1066). Butylhydroxyanisole (Butylated hydroxyanisole) is an antioxidant used as a food additive preservative. Butylhydroxyanisole mediates liver toxicity, retardation in reproductive organ development and learning, and sleep deficit. Butylhydroxyanisole exerts neurotoxic effects and leads to disruption of the brain and nerve development . Butylhydroxyanisole is a ferroptosis inducer .

Host:	Rabbit (2)
Reactivity:	Human (2) Rat (1) Mouse (1)
Application:	IHC-P (2) ICC/IF (1) IP (1) WB (1)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (1) Recombinant (1)
Modification:	Phosphorylated (1) Unmodified (1)

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HY-P80507

	KMT6/EZH2 Antibody (YA320)	IHC-P, ICC/IF	Human
	KMT6/EZH2 Antibody (YA320) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to KMT6/EZH2.

HY-P810576

	Phospho-PPP1CA (Thr320) Antibody (YA9841) Alpha isoform serine threonine protein phosphatase PP1alpha 1 catalytic subunit; Catalytic subunit; PP1A; PP1A_HUMAN; PP1alpha; PP2C ALPHA; PP2CA; Ppp1ca; Protein Phosphatase 2C Alpha Isoform; Serine threonine protein phosphatase PP1 alpha catalytic subunit; Serine threonine protein phosphatase PP1 alpha catalytic subunit protein phosphatase 1; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit.	WB, IHC-P, IP	Human, Mouse, Rat
	Phospho-PPP1CA (Thr320) Antibody (YA9841) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-PPP1CA (Thr320).

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Cat. No.	Product Name		Classification

HY-B1066

Butylhydroxyanisole 5 Publications Verification Butylated hydroxyanisole; E320		Antioxidants
Butylhydroxyanisole (Butylated hydroxyanisole) is an antioxidant used as a food additive preservative. Butylhydroxyanisole mediates liver toxicity, retardation in reproductive organ development and learning, and sleep deficit. Butylhydroxyanisole exerts neurotoxic effects and leads to disruption of the brain and nerve development . Butylhydroxyanisole is a ferroptosis inducer .

HY-N0171B

Beta-Sitosterol (purity>75%) β-Sitosterol (purity>75%); 22,23-Dihydrostigmasterol (purity>75%)		Cholesterol
Beta-Sitosterol (purity>75%) is a phytosterol with oral activity. Beta-Sitosterol (purity>75%) interferes with a variety of cell signaling pathways, including the cell cycle, apoptosis and cell proliferation. Beta-Sitosterol (purity>75%) has anti-inflammatory, antioxidant, and antitumor activities .

HY-R00674

*hsa-miR-320c mimic*		MicroRNAs miRNA mimics
hsa-miR-320c mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R00671

*hsa-miR-320a-3p mimic*		MicroRNAs miRNA mimics
hsa-miR-320a-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI00674

*hsa-miR-320c inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-320c inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R00673

*hsa-miR-320b mimic*		MicroRNAs miRNA mimics
hsa-miR-320b mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R00675

*hsa-miR-320e mimic*		MicroRNAs miRNA mimics
hsa-miR-320e mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R00672

*hsa-miR-320a-5p mimic*		MicroRNAs miRNA mimics
hsa-miR-320a-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RS17653

Cd320 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Cd320 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd320 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS02234

CD320 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CD320 Human Pre-designed siRNA Set A contains three designed siRNAs for CD320 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS24113

Cd320 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Cd320 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cd320 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RI00671

*hsa-miR-320a-3p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-320a-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI00672

*hsa-miR-320a-5p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-320a-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RS00802

APBA1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
APBA1 Human Pre-designed siRNA Set A contains three designed siRNAs for APBA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RI00673

*hsa-miR-320b inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-320b inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI00675

*hsa-miR-320e inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-320e inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R00673A

*hsa-miR-320b agomir*		MicroRNAs miRNA agomirs
hsa-miR-320b agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R00675A

*hsa-miR-320e agomir*		MicroRNAs miRNA agomirs
hsa-miR-320e agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R00674A

*hsa-miR-320c agomir*		MicroRNAs miRNA agomirs
hsa-miR-320c agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI00674A

*hsa-miR-320c antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-320c antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI00673A

*hsa-miR-320b antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-320b antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI00675A

*hsa-miR-320e antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-320e antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R00672A

*hsa-miR-320a-5p agomir*		MicroRNAs miRNA agomirs
hsa-miR-320a-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R00671A

*hsa-miR-320a-3p agomir*		MicroRNAs miRNA agomirs
hsa-miR-320a-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI00671A

*hsa-miR-320a-3p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-320a-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI00672A

*hsa-miR-320a-5p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-320a-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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(3S,5R)-XU 62-320-d6

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