Metaflumizone
Based on 1 Customer Validation
Metaflumizone is a semicarbazone insecticide, acts as a potent sodium channel blocker.
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- Pureté: 95.14%
- CAS No.: 139968-49-3
- Formule: C24H16F6N4O2
- Masse moléculaire:506.40
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Anti-Infection Compound Library
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Neuroprotective Compound Library
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Antiparasitic Compound library
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Sodium Channel Blocker Library
HY-L118
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Human Metabolite Library
HY-L123
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Membrane Protein-targeted Compound Library
HY-L149
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Membrane Receptor-targeted Compound Library
HY-L150
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Ion Channel Compound Library
HY-L166
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Multi-Target Compound Library
HY-L176
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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Pesticide Compound Library
HY-L183
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High-Throughput Bioactive Compound Library
HY-L205
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Mass Spectrometry Human Metabolite Library
HY-L215
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Environmental Pollutant Compound Library
HY-L247
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Activité biologique
Sodium channel[1]
Metaflumizone (10 μM) completely inhibits the Para/TipE sodium currents in Xenopus oocytes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 139968-49-3
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Appearance Solid
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Masse moléculaire 506.40
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Formule C24H16F6N4O2
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Color Light yellow to yellow
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SMILES
FC(F)(F)C1=CC(/C(CC2=CC=C(C=C2)C#N)=N\NC(NC3=CC=C(C=C3)OC(F)(F)F)=O)=CC=C1
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Synonyms
BAS-320I
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvant et solubilité
DMSO : 300 mg/mL (592.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureté et documentation
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Fiche technique (270 KB)
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SDS (459 KB)
- English - EN (459 KB)
- Français - FR (459 KB)
- Deutsch - DE (459 KB)
- Norwegian - NO (459 KB)
- Español - ES (459 KB)
- Swedish - SV (459 KB)
- Italian - IT (459 KB)
- Korean - KR (459 KB)
- Portuguese - PT (459 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9747 mL | 9.8736 mL | 19.7472 mL | 49.3681 mL |
| 5 mM | 0.3949 mL | 1.9747 mL | 3.9494 mL | 9.8736 mL | |
| 10 mM | 0.1975 mL | 0.9874 mL | 1.9747 mL | 4.9368 mL | |
| 15 mM | 0.1316 mL | 0.6582 mL | 1.3165 mL | 3.2912 mL | |
| 20 mM | 0.0987 mL | 0.4937 mL | 0.9874 mL | 2.4684 mL | |
| 25 mM | 0.0790 mL | 0.3949 mL | 0.7899 mL | 1.9747 mL | |
| 30 mM | 0.0658 mL | 0.3291 mL | 0.6582 mL | 1.6456 mL | |
| 40 mM | 0.0494 mL | 0.2468 mL | 0.4937 mL | 1.2342 mL | |
| 50 mM | 0.0395 mL | 0.1975 mL | 0.3949 mL | 0.9874 mL | |
| 60 mM | 0.0329 mL | 0.1646 mL | 0.3291 mL | 0.8228 mL | |
| 80 mM | 0.0247 mL | 0.1234 mL | 0.2468 mL | 0.6171 mL | |
| 100 mM | 0.0197 mL | 0.0987 mL | 0.1975 mL | 0.4937 mL |
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