proMMP-9 inhibitor-3c
proMMP-9 inhibitor-3c (compound 3c) is a potent proMMP-9 inhibitor. proMMP-9 inhibitor-3c is specific for binding to the proMMP-9 hemopexin-like domain (Kd=320 nM). proMMP-9 inhibitor-3c disruption of MMP-9 homodimerization prevents association of proMMP-9 with both α4β1 integrin and CD44 and results in the dissociation of EGFR. This disruption results in decreased phosphorylation of Src and its downstream target proteins focal adhesion kinase (FAK) and paxillin (PAX).
For research use only. We do not sell to patients.
- CAS No.: 2138321-18-1
- Formula: C18H20FN3O2S
- Molecular Weight:361.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2138321-18-1
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Molecular Weight 361.43
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Formula C18H20FN3O2S
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SMILES
O=C(NC1=CC=C(F)C=C1)CCCSC(N2)=NC3=C(CCCC3)C2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
proMMP-9 inhibitor-3c Related Classifications
HY-122585 Related Classifications
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